Cutaneous atypical papular CD8+ lymphoproliferative disorder at acral sites in a renal transplant patient

Summary

A 20-year-old woman presented with a 2-month history of an acute symmetrical eruption, manifesting as asymptomatic ill-defined erythematous macules and hyperkeratotic papules on the palms. The patient was a renal transplant recipient, and the lesions had developed 2 months post-transplantation. Histologically, the eruption shared features of a reactive inflammatory condition called papular eruption of atypical CD8+ lymphocytes as well as primary cutaneous acral CD8+ T-cell lymphoma (a provisional indolent entity in the new World Health Organisation classification of lymphoid neoplasms, 2016). The latter disorder has been described to occur at acral sites in immunocompetent patients, whereas the former has previously been described only in patients infected with human immunodeficiency virus. The lesions in our patient healed after topical treatment with corticosteroids and alteration of immunosuppressive therapy, supporting the role of immunosuppression in this case. We classified our patient's condition as lying in the spectrum of the aforementioned two conditions, but the relationship between both diseases remains to be clarified. Awareness of these unusual conditions may prevent the use of unnecessary aggressive therapies in similar patients.

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Scholar : Obstructive sleep apnea - νέα αποτελέσματα

The Last 25 Years of Obstructive Sleep Apnea Epidemiology—and the Next 25?

PE Peppard, EW Hagen - American Journal of Respiratory and Critical Care …, 2017

Considerable new knowledge regarding the epidemiology of obstructive sleep apnea (OSA)
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Gastric Banding Surgery versus CPAP for Obstructive Sleep Apnea: A Randomized Controlled Trial.

JP Bakker, A Tavakkoli, M Rueschman, W Wang… - American Journal of …, 2017

1 Division of Sleep & Circadian Disorders, Brigham and Women's Hospital; 2 Division of Sleep
Medicine, Harvard Medical School; 3 Center for Weight Management and Metabolic
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Abstract Purpose We report a case of firing a loaded gun during sleep in a geriatric patient
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Z Lou, ZH Lou - European Archives of Oto-Rhino-Laryngology, 2017

Iriz et al. write,"All patients were selected from the subjects undergoing PSG testing after
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R Siber-Hoogeboom, M Schicht, S Hoogeboom… - PloS one, 2017

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AS Almeneessier, Y Almousa, O Hammad, AH Olaish… - Journal of Thoracic Disease, 2017

Background: Obstructive sleep apnea (OSA) during rapid eye movement (REM) sleep is a
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A Van Der Spek, AI Luik, D Kocevska, C Liu… - Frontiers in Genetics, 2017

... Obstructive sleep apnea (OSA) is a common sleep breathing disorder associated with an
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MJ Mador - Journal of Thoracic Disease, 2017

... central sleep apnea (CSA) (classified as treatment emergent CSA) is a well-recognized
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[PDF] Early Variations in Augmentation Index and Pulsed Wave Velocity in Patients with Obstructive Sleep Apnea and Arterial Hypertension Post CPAP Treatment

WA Khalil, A Eldamanhory, W Mansour, MBA Allah - J Cardiol Curr Res, 2017

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left untreated, is associated with high cardiovascular morbidity and mortality. Continuous
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L Nisa, P Teiga, GB da Cunha, B Roy, RO Gunaydin… - European Archives of Oto …, 2017

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Thieme E-Books & E-Journals.

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Scholar : CPAP - νέα αποτελέσματα

Gastric Banding Surgery versus CPAP for Obstructive Sleep Apnea: A Randomized Controlled Trial.

JP Bakker, A Tavakkoli, M Rueschman, W Wang… - American Journal of …, 2017

1 Division of Sleep & Circadian Disorders, Brigham and Women's Hospital; 2 Division of Sleep
Medicine, Harvard Medical School; 3 Center for Weight Management and Metabolic
Surgery, Department of Surgery, Brigham and Women's Hospital; 4 Department of Surgery,

Emergent central sleep apnea during CPAP therapy-clinical implications

MJ Mador - Journal of Thoracic Disease, 2017

Abstract CPAP emergent central sleep apnea (CSA)(classified as treatment emergent CSA)
is a well-recognized phenomenon that has been included in the current edition of the
International Classification of Sleep Disorders (1). It is defined as the presence of primarily

[PDF] Early Variations in Augmentation Index and Pulsed Wave Velocity in Patients with Obstructive Sleep Apnea and Arterial Hypertension Post CPAP Treatment

WA Khalil, A Eldamanhory, W Mansour, MBA Allah - J Cardiol Curr Res, 2017

Abstract Background: Obstructive sleep apnea (OSA) is a risk factor for hypertension and if
left untreated, is associated with high cardiovascular morbidity and mortality. Continuous
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Long-term adherence to continuous positive airway pressure in patients with rapid eye movement-only obstructive sleep apnea: a prospective cohort study

AS Almeneessier, Y Almousa, O Hammad, AH Olaish… - Journal of Thoracic Disease, 2017

... No study has assessed the long-term adherence to continuous positive airway pressure (CPAP)
among patients with REM-only OSA. To objectively assess the long-term adherence to CPAP
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Laryngopharyngeal reflux is a potential cause of nasal congestion and obstructive sleep apnea syndrome

Z Lou, ZH Lou - European Archives of Oto-Rhino-Laryngology, 2017

... CPAP therapy was offered for all patients with OSAS, but only 26 patients accepted. ... Most
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Y ZHANG, D CHEN, L ZHU, D XU, H WANG, L LIU - Chinese Journal of …, 2017

... Yu ZHANG, Deng CHEN, Li-na ZHU, Da XU, Hai-jiao WANG, Ling LIU. Abstract. Objective
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Long term oral appliance therapy improves daytime function and mood in Upper Airway Resistance Syndrome patients

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... 3. Process capability index CpAP In this section, a new PCI CpAP will be developed
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MKH Shabuj, SC Moni, I Jahan, SK Dey, MA Mannan… - Journal of Clinical …, 2017

... to December2016. We included a total of 148 neonates with positive-pressure
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ть е рыв ж ть

M Light, K McCowen, A Malhotra, OA Mesarwi - 2017

... Nasal continuous positive airway pressure (CPAP) has long been the mainstay of therapy for OSA,
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