Meetings Calendar 2018

Rejuvenation Research, Ahead of Print.


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How certainty appraisal might improve both body dissatisfaction and body overestimation in anorexia nervosa: a case report

Abstract

Background

Patients with anorexia nervosa often report a conscious alteration of body image representation, with both body overestimation and body dissatisfaction. Cognitive and behavioural therapy is effective for treating many psychiatric disorders but often fails to treat anorexia nervosa and body image distortions. Although patients are aware of their weight loss, they continue to feel overweight - as if there were a conflict between a previous (maybe already false) body representation and the new one. These distortions are linked to negative emotions focused on the body but which can extend to the self (e.g. disgust and sadness).

Case Presentation

The present case report is the first in which the Appraisal Tendency Framework has been applied to decrease body image distortions in a patient with anorexia nervosa. The Appraisal Tendency Framework is usually used to understand how emotions influence decision making. Here, we report on a 24-year-old woman who suffered from anorexia nervosa and body image distortions, and was treated as an inpatient with conventional cognitive and behavioural therapy for an eating disorder. Body image distortions were assessed before and after the patient completed an adaptation of the Iowa Gambling Task, coupled with the induction of a heuristic processing emotion. We hypothesized that allowing the patient to focus on the emotional cues in the modified Iowa Gambling Task would improve her decisions about her true body shape.

Conclusion

All body image measures were improved after the protocol. Consequently, we suggest that the Appraisal Tendency Framework might be a valuable means of investigating body image issues in eating disorders and anorexia nervosa. Further studies are required to expand and detail these findings.

https://ift.tt/2RrFqIP

Congenital absence of the deep inferior epigastric system: a case report

Abstract

Preoperative computerised tomographic angiography (CTA) in free flap breast reconstruction outlines the deep inferior epigastric perforator (DIEP). It can identify a single or twin system, measure vessel calibre, and identify iatrogenic/congenital anatomical variations. Evidence of the effect of previous abdominal incisions on this vessel system remain inconclusive. We present the case of a congenital absence of the system identified from routine preoperative CTA. A 61-year-old female presented for immediate unilateral breast reconstruction following mastectomy for ductal carcinoma in situ. She previously had a right-sided Kocher's incision performed for an open cholecystectomy and a gridiron incision. Coincidentally, preoperative CTA demonstrated congenital absence of the left DIEP system, and marked atrophy of the upper right rectus abdominis (RA). As a result, the superior gluteal artery perforator (SGAP) flap was planned. Intraoperatively, a 1.318-kg SGAP was raised on three perforators and coupled to the internal mammary vessels. In the postoperative period, there were no complications. Preoperative CTA demonstrated multiple hazards in raising a DIEP flap, CTA permitted surgical planning, improving patient safety and surgical efficiency. Preoperative CTA identifies vessel abnormalities resulting from abdominal scarring. The rate of congenital anomalies is unknown. This incidental discovery highlights the role CTA has in reducing operative time, facilitating a successful free tissue transfer, therefore improving patient safety.

Level of Evidence: Level V, diagnostic study.

https://ift.tt/2IFGm8r

Risk assessment of some organic contaminants: a case study based on food consumption in Tanta and Ismailia cities, Egypt

Abstract

The impact of some organic pollutants on some residents of Tanta and Ismailia cities of Egypt through their consumption of vegetables, fruits and fish (Nile tilapia and catfish) was examined. Residues of organochlorine (OC_S) and organophosphorus (OP_S) as some polychlorinated biphenyls (PCB_S) were compared with pesticides as well maximum residue limits (MRL_S). Probable health risk to consumers was also assessed. P, P′-DDT, P, P′-DDE, P, P′-DDD, endrin, α-BHC, (lindane), and hexachlorbenzene (HCB) were the most detected organochlorine compounds, but did not exceed MRLs.

However, OP_S residues were the most frequently detected contaminants. PCBs congeners 28, 70, 52, and 180 were detected in tilapia fish from Tanta, but congeners 28 and 180 were the only detected congeners in samples collected from Ismailia region. ∑PCB_S values in all matrices did not exceed MRL_S. Hazard index (HI) exhibited unity for all compounds at 50 the decreasing order: catfish > vegetables > fruits > Nile tilapia in Tanta, while in Ismailia the order was Nile tilapia > fruit > vegetables. Results also revealed that risk values for adults were greater than those of children categories.

https://ift.tt/2RpwEuS

Thyroid® High-Impact Articles

FREE ACCESS

Read now:

Latest Impact Factor: 7.557
The Official Journal of: American Thyroid Association^®

Incidences of Unfavorable Events in the Management of Low-Risk Papillary Microcarcinoma of the Thyroid by Active Surveillance Versus Immediate Surgery
Hitomi Oda, Akira Miyauchi, Yasuhiro Ito, Kana Yoshioka, Ayako Nakayama, Hisanori Sasai, Hiroo Masuoka, Tomonori Yabuta, Mitsuhiro Fukushima, Takuya Higashiyama, Minoru Kihara, Kaoru Kobayashi, and Akihiro Miya 

A Clinical Framework to Facilitate Risk Stratification When Considering an Active Surveillance Alternative to Immediate Biopsy and Surgery in Papillary Microcarcinoma
Juan P. Brito, Yasuhiro Ito, Akira Miyauchi, and R. Michael Tuttle 

Subclinical Hypothyroidism in Pregnancy: A Systematic Review and Meta-Analysis
Spyridoula Maraka, Naykky M. Singh Ospina, Derek T. O'Keeffe, Ana E. Espinosa De Ycaza, Michael R. Gionfriddo, Patricia J. Erwin, Charles C. Coddington III, Marius N. Stan, M. Hassan Murad, and Victor M. Montori 

Preoperative Cytologic Diagnosis of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Prospective Analysis
Kyle C. Strickland, Marina Vivero, Vickie Y. Jo, Alarice C. Lowe, Monica Hollowell, Xiaohua Qian, Tad J. Wieczorek, Christopher A. French, Lisa A. Teot, Peter M. Sadow, Erik K. Alexander, Edmund S. Cibas, Justine A. Barletta, and Jeffrey F. Krane 

An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer
Iain J. Nixon, Laura Y. Wang, Jocelyn C. Migliacci, Antoine Eskander, Michael J. Campbell, Ahmad Aniss, Lilah Morris, Fernanda Vaisman, Rossana Corbo, Denise Momesso, Mario Vaisman, Andre Carvalho, Diana Learoyd, William D. Leslie, Richard W. Nason, Deborah Kuk, Volkert Wreesmann, Luc Morris, Frank L. Palmer, Ian Ganly, Snehal G. Patel, Bhuvanesh Singh, R. Michael Tuttle, Ashok R. Shaha, Mithat Gönen, K. Alok Pathak, Wen T. Shen, Mark Sywak, Luis Kowalski, Jeremy Freeman, Nancy Perrier, and Jatin P. Shah 

Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier
Kristine S. Wong, Trevor E. Angell, Kyle C. Strickland, Erik K. Alexander, Edmund S. Cibas, Jeffrey F. Krane, and Justine A. Barletta 

Clinical and Pathologic Predictors of Lymph Node Metastasis and Recurrence in Papillary Thyroid Microcarcinoma
Saaduddin Siddiqui, Michael G. White, Tatjana Antic, Raymon H. Grogan, Peter Angelos, Edwin L. Kaplan, and Nicole A. Cipriani 

The 2017 Bethesda System for Reporting Thyroid Cytopathology
Edmund S. Cibas and Syed Z. Ali 

 

The post <i>Thyroid^®</i> High-Impact Articles appeared first on American Thyroid Association.

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Anatomy of the Superficial Venous Structures of the Neck: A Cadaveric Study to Guide Superficial Injections

BACKGROUND Minimally invasive aesthetic procedures of the neck are becoming more popular. However, anatomical studies on the venous structures of the neck in relation to these procedures are lacking. OBJECTIVE The aims of this study were to identify the locations and communication patterns of the anterior jugular vein and external jugular vein (AJV and EJV) and the communicating vein (CV) based on superficial anatomical landmarks and to determine dangerous areas for dermal filler injections into the neck. MATERIALS AND METHODS Thirty sides of the neck from Korean adult cadavers were dissected for this study. RESULTS Four anatomical variants were identified. In Type Ia, the CV ran along the anterior border of the sternocleidomastoid muscle (SCM) (33.4%); in Type Ib, a single vein was observed connecting the CV and the EJV at the level of laryngeal prominence (23.3%); in Type Ic, the CV proceeded separately from the medial side of the anterior border of the SCM (13.3%); and in Type II, the CV was absent while the EJV and AJV were observed (30%). CONCLUSION Given the 4 anatomical variants identified in this study, the authors recommend exerting caution when performing dermal filler injections approximately 10, 30, and 60 mm lateral to the midsagittal line to avoid iatrogenic side effects. Address correspondence and reprint requests to: Kyung-Seok Hu, DDS, PhD, Room 601, Department of Oral Biology, Yonsei University College of Dentistry 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea, or e-mail: hks318@yuhs.ac Supported by a faculty research grant of Yonsei University College of Dentistry (6-2016-0027). The authors have indicated no significant interest with commercial supporters. H.-J. Lee and S.-Y. Ryu have contributed equally to this work. © 2018 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Activation of peroxymonosulfate by Fe-N complexes embedded within SBA-15 for removal of organic contaminants via production of singlet oxygen

Abstract

Persulfates are recognized as promising oxidants and an alternative to Fenton reaction for water treatment. However, activation methods in hand restrict the practical application. Herein, we explore the possibility of Fe-N complexes being a catalyst for persulfate activation for the first time. The catalyst denoted as Fe-Im-SBA was synthesized from ferric chloride, imidazole, and SBA-15 at high temperature. The internal pore structure of Fe-Im-SBA was maintained well; Fe, N and C elements are evenly distributed on the catalyst. This catalyst presents an extraordinarily catalytic activity for Rh B removal by PMS activation with a removal rate of Rh B that reached up to 97.0% in the first 5 min. It also performed well in a wide pH range with complete removal of Rh B in pH ranged from 0.5 to 10, suggesting the stability of this catalyst in both acidic and alkaline conditions. It also showed high adaptability to degrade different kinds of pollutants, which could give an attractive advantage of Fe-Im-SBA for environmental implications. Through X-ray absorption spectroscopies analysis, it shows that the active sites of Fe-Im-SBA are composed of Fe-N₄ sites and Fe₂–N₂ sites. ¹O₂ were proved to generate in the Fe-Im-SBA/PMS system and serve as the major ROS. Meanwhile, graphitic carbon can accelerate the transfer of electrons, which may also be the reason for its high catalytic performance.

https://ift.tt/2y0VCIR

Distribution of organic and inorganic mercury in the tissues and organs of fish from the southern Baltic Sea

Abstract

The aim of this study was to determine the distribution of total mercury (THg), methylmercury (CH₃Hg⁺), and inorganic mercury (Hg_inorg) in the tissues and organs of fish depending on species, tissue, and organ, and their bioaccumulation in tissues and biomagnification throughout the trophic web. The study included four species of fish (herring, sprat, cod, and eel) from the southern Baltic Sea. The concentrations of the different forms of mercury were determined in tissues and internal organs. Intra-specific differences in levels of THg, CH₃Hg⁺, and Hg_inorg in the tissues and organs were determined. Muscle contained the highest proportions of THg and CH₃Hg⁺ in comparison to that in the internal organs. Differences in concentrations of THg, CH₃Hg⁺, and Hg_inorg in the tissues and organs of fish were related to their preferred prey. The bioaccumulation of CH₃Hg+ in the tissues and organs of predatory fish at the highest trophic levels was greater than in the liver and digestive tract of fish species at lower trophic levels, in which Hg_inorg predominated. The high concentrations of CH₃Hg⁺ in eel and cod and the low levels in herring and sprat were linked with their food and the transfer of this element among species. The results suggested that the type of food, feeding habits, and trophic position were important parameters that influenced the transfer and biomagnification of mercury in fish.

https://ift.tt/2Pc5QN2

Dietary propionic acid enhances antibacterial and immunomodulatory effects of oxytetracycline on Nile tilapia, Oreochromis niloticus

Abstract

This study was carried out to evaluate the potential antibacterial and immunomodulatory effects of the dietary acidifier propionic acid (PA) when given alone or in combination with oxytetracycline (OTC) on Nile tilapia (Oreochromis niloticus). Apparently healthy O. niloticus (n = 240; 52 ± 3.75 g) were randomly allocated into four equal groups (n = 60/group): control group fed a basal diet alone and the other three groups fed basal diets supplemented with either PA (200 mg /kg of diet, PA group) or OTC (500 mg/kg of diet, OTC group) alone or in combination (PA + OTC group). Each group was subdivided into two subgroups (n = 30/subgroup, each subgroup had triplicate of 10 fish); subgroup (A) was used to evaluate the antibacterial effects with the aforementioned 2 weeks feeding regime, and subgroup (B) was used to evaluate the immunomodulatory effects against Aeromonas hydrophila infection with similar 2 weeks feeding regime. Among the four groups, PA + OTC group showed the highest significant (p < 0.0001) antibacterial activity as indicated by widest inhibition zones against A. hydrophila and lowest total gastrointestinal bacterial counts. Additionally, this group had the best immunomodulatory effect as noticed by a significant (p < 0.05) increase in total serum protein, globulin, IgM, phagocytic activity and index, lysosome activity, and significant (p < 0.05) upregulation in the expression levels of immunity-related genes (MHC I, MHC IIA, MHC IIB, Tlr7, IgM heavy chain, TNFα, and IL1β) in head-kidney. Notably, the combined dietary PA and OTC improved the hematological parameters and reduced the oxidative damage of hepatopancreas and head-kidney induced by OTC. This data suggests dietary PA as potential adjuvant to OTC in O. niloticus diets to get maximal antibacterial and immunomodulatory effects.

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The scratch collapse test: a systematic review

The diagnosis of nerve compression relies on collecting diagnostic clues from the history, physical exam, imaging, and diagnostic testing. There are several provocative tests to aide in the diagnosis of nerve compression. The 'Scratch Collapse Test' (SCT) has emerged as a new provocative test to assist in the localization of peripheral nerve compression. This study aims to perform a systematic review of the literature to assess the data on the reliability of the SCT as a diagnostic test for entrapment neuropathy.

https://ift.tt/2Nli4kZ

Distances of root apices to adjacent anatomical structures in the anterior maxilla: an analysis using cone beam computed tomography

Abstract

Objectives

The aim was to assess the anatomical relationship of anterior maxillary teeth to the nasal floor in patients referred for apical surgery.

Materials and methods

Cone beam computed tomographic images (CBCT) of 83 patients were analysed retrospectively to quantify the distances between the root apices of maxillary anterior teeth (canine to canine) to the nasal floor or maxillary sinus (whichever was closer). Secondary outcome variables were the distances of the periapical lesion to the nasal floor, distances of the apices to the labial and palatal bone plates as well as to the neighbouring teeth.

Results

A total of 93 teeth (39 central, 35 lateral incisors and 19 canines) were analysed. The mean shortest distances of the apices to the nasal floor (or maxillary sinus) were 8.54 mm for central incisors, 9.49 mm for lateral incisors and 5.39 mm for the canines. The canines exhibited a significantly shorter distance to the nasal floor/maxillary sinus. In the presence of an osteolysis, the distance to the nasal floor was significantly shorter compared to the teeth without lesions. The lateral and central incisors showed significant proximity to each other at the level of the future surgical resection (3 mm from the apex).

Conclusions

A close proximity between apices and adjacent anatomical structures such as nasal floor, maxillary sinus or adjacent roots could be shown in some cases.

Clinical relevance

CBCT could be a valuable adjunctive imaging tool prior to apical surgery in the anterior maxilla to assess the risk for and decrease the incidence of damage to neighbouring anatomical structures such as the nasal floor, maxillary sinus or adjacent roots.

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Lipid organization in xerosis: The key of the problem?

International Journal of Cosmetic Science, Volume 0, Issue ja, -Not available-.


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William T. O’Brien Sr. Top 3 Differentials in Radiology. A Case Review

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Stress distribution in mandibular donor site after harvesting bone grafts of various sizes from the ascending ramus of a dentate mandible by finite element analysis

Abstract

Purpose

Harvesting bone from the ascending ramus of the mandible is a common procedure. However, mandibular fracture may occur after grafting bone blocks. This study aimed to investigate the resulting force distribution of stress and strain in the mandibular donor site after harvesting bone grafts of different sizes and various loadings.

Methods

Finite element analysis was performed for virtual harvesting of bone blocks of nine different sizes between 15 × 20 and 25 × 30 mm and three different chewing loads (incisal, ipsilateral and contralateral). von Mises stress and first principal stress distributions were measured.

Results

von Mises stress was distributed between 35.01 (10 × 15 mm graft, incisal load) and 333.25 MPa (30 × 20 mm graft ipsilateral load), whereas first principal stress distributions were between 48.27 (10 × 15 mm graft, incisal load) and 414.69 MPa (30 × 20 mm graft ipsilateral load). In general, the least stress was observed with incisal load followed by ipsilateral load and finally contralateral load. The critical value of 133 MPa was found after removing almost all grafts with a width of 20 or 30 mm.

Conclusions

Incisal loading led to less stress compared with contralateral and ipsilateral loads. Increasing graft size led to increasing weakness of the donor site. Graft width exerted a greater influence on stress development than its height.

Clinical relevance

Ipsilateral chewing and increasing width of the bone graft result in maximum stress in the mandibular donor side, and critical values regarding to the possibility of fractures are already to expect from a graft size of 20 × 15 mm.

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Skin Eruptions in an HIV-Positive Man Receiving Pembrolizumab

An HIV-positive man in his 30s being treated with pembrolizumab for metastatic programmed cell death ligand 1–positive squamous non–small cell lung cancer presents with pruritic, mildly painful, hyperpigmented papules and plaques on both feet. What is your diagnosis?

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Cognitive Impairment Among Older Patients With Hematologic Cancers—Reply

In Reply We appreciate the careful reading of our study by Tanimoto and colleagues and the provocative points they raise. We agree that marked anemia at the time of presentation might influence the physical and/or cognitive function of older patients with blood cancer. In this context, we have now assessed for a potential association between clinically significant anemia (hemoglobin ≤8 g/dL) and outcomes in the cohort of older patients with hematologic cancers in our study. We found no correlation between anemia and survival (χ² = 1.07; P = .30), and no correlation between anemia and frailty status (robust vs prefrail/frail) as defined by the Fried phenotype (χ² = 2.66; P = .10). Finally, we found no correlation between anemia (hemoglobin ≤8 g/dL) and a positive screening test for probable cognitive impairment by 5-word delayed recall (χ² = 0.91; P = .34), even though impaired delayed recall was associated with worse overall survival in our study.

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Aspirin and Chemoprevention—Have We Arrived?

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How Pharmacy Benefit Managers Add to Financial Toxicity

This Viewpoint examines the role of benefit managers and other mechanisms driving the sustained increases in prescription drug costs in the United States.

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Erectile Dysfunction in Male Survivors of Childhood Cancer

This survey study evaluates the presence of erectile dysfunction in men who had experienced cancer during childhood.

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Analgesic Use and Risk of Ovarian Cancer in the Nurses’ Health Studies

This cohort study uses data from the Nurses' Health Studies to evaluate associations between use of nonsteroidal anti-inflammatory drugs and risk of epithelial ovarian cancer.

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Cognitive Impairment Among Older Patients With Hematologic Cancers

To the Editor Dr Hshieh and colleagues found that, among 360 patients 75 years and older with hematologic cancer, 127 (35.3%) had probable executive dysfunction and 62 (17.2%) had probable impairment in working memory. Executive dysfunction was associated with worse survival only among patients who underwent intensive treatment, and impairment in working memory was associated with worse median (SD) survival in the overall cohort (10.9 [12.9] vs 12.2 [14.7] months; log-rank P < .001) and after adjusting for age, comorbidities, and disease aggressiveness (odds ratio, 0.26; 95% CI, 0.13-0.50). We believe that the results merit the following comments and discussion.

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Long Live Neutrophil

Memories are faint, for words were fewOr maybe it was me, hearing nothing I knewLost somewhere in jargon of marrow, purpura, blastWas lurking my cancer, as we stood speechless, aghastTherapy would last for months, we were sent to 10-WestStressing me was my homework, algebra and science are my best"I have got things to do," I play treasure hunt and catchTim's birthday was around, and my baseball matchSitting in the care room, listening about the trialsI knew it was time to endure, no more screams or denials.

https://ift.tt/2DXy258

Association Between Aspirin Use and Risk of Hepatocellular Carcinoma

This pooled analysis of the Nurses' Health Study and the Health Professionals Follow-up Study examines the association between long-term use of aspirin and the development of hepatocellular carcinoma in adult men and women.

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Leaders In Plastic Surgery The Dingman-Grabb Era 1946-1986. By Robert M. Oneal MD and Lauralee A. Lutz. Pp. 202. Michigan Publishing, Ann Arbor, MI., 2017. Price $19.99.

No abstract available

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Minimal pain with Prepectoral implant based breast reconstruction

No abstract available

https://ift.tt/2Pa05j5

Does reconstruction preserving the first or first two rays benefit over full transmetatarsal amputation in diabetic foot?

Background: The benefits of total transmetatarsal amputation (TMA) over higher level amputation are well known. However, there are no studies evaluating the effects of first or the first two ray sparing transmetatarsal amputation with flap coverage. We evaluated this approach in regards to functional outcome and to identify long-term complications. Material and Method: Retrospective data of 59 patients were evaluated according to their surgical method. Complete TMA with free flap reconstruction was designated as group TMA with 27 patients and first or first two rays preserving TMA with free flap reconstruction was designated as group Ray with 32 patients. Demographics, flap outcomes, additional procedures after initial healing and functional outcomes were measured and evaluated. Results: There was no statistical significant difference in demographic distribution and flap outcomes in either group except poor blood sugar control in group Ray. Additional procedures after initial healing showed no statistical difference but the tendency of minor procedures was higher in group Ray. The maximum achieved ambulatory function was significantly better in group Ray with an ambulatory function score of 4.4 over 3.7 in group TMA (p= 0.012). Conclusion: The preservation of the first or first two rays with free flap reconstruction may functionally benefit the patients despite the higher tendency of minor procedures after initial healing. Furthermore, the progressive deformity of the preserved first and second toes will inevitably occur requiring patients to undergo further surgery. Further studies are warranted to evaluate this approach. Conflict of interest: The authors have no conflict of interest of any kind regarding this article. Address correspondence to: Joon Pio Hong, M.D., Ph.D., M.M.M., Professor, Department of Plastic and Reconstructive Surgery, University of Ulsan, College of Medicine, Asan Medical Center, 88 Olympic-ro 43 gil, SongPa-Gu, Seoul 05505, Korea. ©2018American Society of Plastic Surgeons

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Current Use of Biological Scaffolds in Plastic Surgery

Properly designed biodegradable scaffolds facilitate repair or regeneration of stromal tissues. Over the last 50 years, a variety of synthetic, semi-synthetic and decellularized scaffolds have been developed that provide surgeons with tools to reconstruct a wide array of structural defects. We reviewed the literature of biological degradable scaffolds in current clinical use in the US and highlight their design principles as well as products in common use. Host tissues populate scaffolds with inflammatory cells, fibroblasts, blood vessels, nerves and lymphatics. Cells lay down extracellular matrix macromolecules while enzymes degrade the scaffold. Over time the scaffold can be totally replaced by host tissues. The greatest use of scaffolds in plastic surgery is in skin replacement, breast reconstruction, abdominal wall reconstruction and peripheral nerve repair. Other areas of importance are cartilage and bone replacement as well as support for lining replacements such bowel, bladder, mucosa and dura. The wide range of research being done in this field is likely to provide surgeons with more choices and improved materials to repair and regenerate stromal structures. Disclosure: Dr. Orgill receives research funding through grants to Brigham and Women's Hospital from ACell Inc., Integra LifeSciences, Inc. and the Musculoskeletal Transplant Foundation. He is a consultant for Integra LifeSciences Inc., the Musculoskeletal Transplant Foundation (MTF) and Geistlich Pharma North America Inc. All other authors declare no actual or potential conflict of interests: in addition they disclose no commercial or financial associations, personal or other relationships with other people or organizations that could inappropriately influence the reported manuscript or create a conflict of interest with the information presented. Corresponding author: Dennis P. Orgill, M.D., Ph.D., Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital - Harvard Medical School, 75 Francis St., Boston MA 02115, T: 617-525-7837, Email: dorgill@partners.org ©2018American Society of Plastic Surgeons

https://ift.tt/2P8Ys56

Assessing Quality of Life and Patient-Reported Satisfaction with Masculinizing Top Surgery: A Mixed-Methods Descriptive Survey Study

Background: Masculinizing top surgery (bilateral mastectomy with chest wall reconstruction) is an important gender-affirming procedure sought by many transmasculine and non-binary individuals. Current literature is primarily focused on details of surgical technique and complication rates, with limited data available on how top surgery affects subjective quality of life measures. Methods: An anonymous online survey was distributed to 81 of the senior author's former top surgery patients. Survey response rate was 72% (58 respondents). Responses were analyzed to investigate quality of life, sexual confidence, mental health, satisfaction with top surgery, and patient attitudes toward top surgery's role in gender affirmation. Results: Following top surgery, measures of quality of life and sexual confidence significantly improved (P

https://ift.tt/2xXxpDm

Spotlight in Plastic Surgery: January 2019

No abstract available

https://ift.tt/2P7zS4M

Reporting Adverse Events in Plastic Surgery: A Systematic Review of Randomized Controlled Trials

Background: Accurate knowledge of adverse events is critical for evaluation of the safety and efficacy of interventions. Historically, adverse events in surgical trials have been poorly reported. The objective of this study was to systematically evaluate the reporting of adverse events in randomized controlled trials (RCTs) in the plastic surgery literature. Methods: Two independent reviewers conducted a systematic search using MEDLINE, EMBASE, and SCOPUS of the top seven plastic surgery journals with the highest impact factors. RCTs describing a potentially invasive treatment, published between January 2012 and December 2016, were included. Results: One hundred and forty-five RCTs involving 10,266 patients were included, of which 30% were registered. Anticipated adverse events were clearly defined in 15% of trials, and in 70% it was not clear who would be documenting adverse events. Furthermore, 72% of RCTs reported the occurrence of adverse events, of which 61% failed to report events occurring in the intra-interventional period. Of the trials not documenting any adverse event, two-thirds included a statement declaring that no adverse events had occurred. Binary logistic regression revealed that funded RCTs were 4.04 times more likely to report adverse events compared to non-funded RCTs (95% CI 1.41-10.83, p=0.009). Conclusions: Our findings suggest the need for reporting standards for adverse events in the plastic surgery literature, as such reporting remains heterogeneous and is lacking rigor. Improved quality and transparency is needed to strengthen evidenced-based practice and permit a balanced intervention assessment. This study provides a set of recommendations aimed at improving adverse event reporting. Financial Disclosure Statement: The authors have no financial disclosures to declare. Presentation: This article was accepted for presentation at the 71st annual Canadian Society of Plastic Surgeons Meeting in Winnipeg, MB Canada. Corresponding Author: Jason G. Williams, MD MEd FRCSC, Division of Plastic Surgery, Dalhousie University, QEII Health Sciences Centre, Halifax Infirmary, 4447, 1796 Summer Street, Halifax, Nova Scotia, Canada, B3H 3A7, Tel: +1-(902)-473-6315, E-mail address: drjwilliams@gmail.com ©2018American Society of Plastic Surgeons

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Tips for Making a Successful Online Microsurgery Educational Platform – The Experience of International Microsurgery Club

The presence of online learning resources has grown tremendously in recent years. They provide powerful and yet easily accessible means of learning and sharing knowledge. Online learning resources now encompass all aspects of medicine, and microsurgery is no exception. International Microsurgery Club (IMC) is a closed, invitation-only group based on the Facebook social media platform. It was initiated on May 6, 2016, with primary objectives of providing a convenient forum for discussing challenging cases, sharing valuable resources, and providing opportunities for research collaboration. The membership of IMC has grown over 8700 at two year of existence, and continues to expand. IMC has become one of the largest online platforms for global microsurgeons. Here, we share our experience on how to establish a successful online platform for medical education. Financial disclosure statement: None of the authors have financial interests in any of the products, devices, or drugs mentioned in this manuscript. This article has been presented at the World Society for Reconstructive Microsurgery, 2017, Seoul, South Korea. Correspondence author and requests for reprints: Tommy Nai-Jen Chang, M.D. Assistant Professor, Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, No. 5, Fu-Hsing St. Kwei-Shan, Taoyuan, Taiwan. Tel: 886-3-3281200 Ext. 3355, Fax: 886-3-3289582, E-mail: tommynjchang@yahoo.com.tw ©2018American Society of Plastic Surgeons

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Afatinib and Pembrolizumab for Head and Neck Squamous Cell Carcinoma (ALPHA Study)

Condition:   Head and Neck Neoplasms
Interventions:   Drug: Afatinib Oral Tablet;   Drug: Pembrolizumab Injection
Sponsor:   National Taiwan University Hospital
Not yet recruiting

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Reviewers’ list December 2018

Publication date: Available online 4 October 2018

Source: Journal of the American Academy of Dermatology

Author(s):

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Summer fallow increases loss of residual nitrogen fertilizer in dryland of the Loess Plateau: a 15 N-labeled method

Abstract

Summer fallow is very common in dryland agriculture to conserve rainwater and replenish soil fertility. However, bare land and intensive rainfall during summer fallow might result in a potential risk of N loss. We used a ¹⁵N-labelling method to study the loss of residual N fertilizer during summer fallow and its use by next wheat in the Loess Plateau. Our study included three treatments: without the addition of N (N₀W₀), with the addition of 50 kg ha⁻¹ N (NW₀) and with the addition of 50 kg ha⁻¹ N plus 35% more water (NW). The N fertilizer (K¹⁵NO₃) in solution was injected into the soil at a depth of 35 cm of the polyvinyl chloride (PVC) columns in field. The fates of ¹⁵N were followed after summer fallow and in the next season's wheat (Triticum aestivum L.). The summer fallow of this study was a dry summer; however, fertilizer ¹⁵N was still leached down to 40-cm depth for the NW₀ treatment; and for the NW treatment, the peak of ¹⁵N fertilizer was approximately 20 cm deeper. After summer fallow, the loss of the initially applied ¹⁵N was 26% in the soil profile for the NW₀ treatment; and for the NW treatment, it increased to 37%. Soil ¹⁵N abundance in 0–20 cm of the NW₀ and NW treatments was higher than the N₀W₀ treatment, indicating the upward movement of ¹⁵N in summer fallow. After the next wheat harvest, ¹⁵N uptake by wheat in the NW treatment decreased from 21.0 to 18.6% compared to the NW₀ treatment. High rainfall during summer fallow increased residual N loss during summer fallow but decreased its use by the next crop.

https://ift.tt/2O6SBAQ

Effective reduction of metronidazole over the cryptomelane-type manganese oxide octahedral molecular sieve (K-OMS-2) catalyst: facile synthesis, experimental design and modeling, statistical analysis, and identification of by-products

Abstract

High concentrations of antibiotic compounds within pharmaceutical wastewater have hazardous impacts toward environment and human health. Therefore, there is an immediate requirement of efficient treatment method for removal of antibiotics from aquatic environment. In the present study, the cryptomelane catalyst-type manganese oxide octahedral molecular sieve (K-OMS-2) was synthesized in the presence of benzyl alcohol as a reducing agent and cetyltrimethylammonium bromide as a structure-directing agent and then utilized to reduce the metronidazole. The central composite design method was the experimental design adopted. The FESEM analysis revealed that the K-OMS-2 surface contained many uniformly cylindrical aggregates less than about 40 nm in diameter and about 80–100 nm in length. Besides, a high specific surface area of 129 m²/g and average pore size of 45.47 nm were recorded. According to the TGA/DTA analysis, the prepared catalyst revealed high thermal stability. The maximum metronidazole degradation (95.36%) was evident at conditions of pH = 3, catalyst mass = 0.97 g/L, contact time = 200 min, and metronidazole concentration = 20 mg/L. Metronidazole did not form a complex with nitrate, fluoride, sulfate, or hardness. These ions exerted a negligible effect on metronidazole reduction using the K-OMS-2 catalyst, except for hardness, which reduced the removal efficiency of metronidazole by 17%. The FTIR and LC-MS revealed a complex mechanism involved in the metronidazole degradation by the K-OMS-2 involving the formation of an amino group, a hydroxyelated compound via N-denitration, and hydrogenation process on the K-OMS-2 catalyst surface.

https://ift.tt/2NkTOzl

Scholar : These new articles for Environmental Claims Journal are available online

The online platform for Taylor & Francis Online content New for Environmental Claims Journal and online now on Taylor & Francis Online: Articles Emerging Green Synergy in the Science/Religion Relationship: From Conflict to Potentially Planet-Saving Cooperation Robert A. Michaels, Richard A. Hammerman & Heslley M. Silva Pages: 1-23 | DOI: 10.1080/10406026.2018.1504381 Hoping to have your article read by anyone, anywhere and at any time? Find out more about publishing open access with Ecosystem Health and Sustainability. To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Early plant growth and bacterial community in rhizoplane of wheat and flax exposed to silver and titanium dioxide nanoparticles

Abstract

Silver and titanium dioxide nanoparticles (AgNPs and TiO₂NPs) are highly useful, but they are also a significant reason for concern as they exert toxicity. The goal of research was to assess the role of three kinds of NPs in concentrations of 100 mg L⁻¹ on early growth plants (wheat, flax) and bacterial community in rhizoplane. Titanium (IV) oxide anatase (TiO₂NPs1) and titanium (IV) oxide nanopowder (TiO₂NPs2) are commercial products. A suspension of AgNPs was prepared via a procedure of reduction with tannic acid. The response of Monocot and Dicot growth form plants to the tested NPs was different. Germination and seedling growth of wheat treated with TiO₂NPs1 was better. The response of flax to NPs was noted as an increase of chlorophyll content. The bacterial community in wheat rhizoplane was not significantly modified, but there was a declining trend. In turn, a difference in the surface charge of NPs had an influence on the total bacterial community in Dicot rhizoplane. Positively charged TiO₂NPs2 significantly decreased the quantity of total bacteria in contrast to negatively charged AgNPs and TiO₂NPs1 which increased it. A qualitative analysis did not confirm the influence of the surface charge of NPs on an increase/decrease in the quantity of Pseudomonas and Bacillus bacteria, but did show that there was no toxicity of the tested NPs to the plant growth-promoting bacteria community. The rhizoplane microbiome was dependent on the species of plant, and the bacteria found in the communities are sensitive to NPs to a varying degree.

https://ift.tt/2O4KULp

Particulate matter air pollution and respiratory impact on humans and animals

Abstract

Air pollution is now fully acknowledged to be a public health problem and a social issue. Particulate matter (PM) concentration has been linked with several clinical manifestations of pulmonary and cardiovascular diseases and is associated with morbidity and mortality induced by respiratory diseases both in human and animals. Current research on airborne particle-induced health effects investigates the critical characteristics of particulate matter that determine their biological effects. Scientific evidence assessed that the size of the airborne particles and their surface area determine the potential to elicit inflammatory injury, oxidative damage, and other biological effects. Thus, the present review paper aims to summarize the current evidences and findings on the effect of air pollution on lung function in both humans and animals.

https://ift.tt/2Nl3x8U

Efficacy of phototherapy in pityriasis lichenoides chronica of dark skin: A retrospective study from a tertiary center in Mexico

Dermatologic Therapy, EarlyView.


https://ift.tt/2xTDLDN

Advancing EJNMMI: continuing success and next developments

https://ift.tt/2O5aQXy

Antifungal efficacy of photodynamic therapy with TONS 504 for pathogenic filamentous fungi

Abstract

The pathogenic filamentous fungi Fusarium solani (F. solani) and Aspergillus fumigatus (A. fumigatus) are common causes of fungal keratitis. We have here evaluated the antifungal efficacy of photodynamic antimicrobial chemotherapy (PACT) with the novel chlorin derivative TONS 504 and a light-emitting diode (LED) with a wavelength of 660 nm for these fungal species. Isolated fungal spores were irradiated at LED energies of 10, 20, or 30 J/cm² in the presence of TONS 504 at concentrations of 1 or 10 mg/L. As a control, spores were exposed to TONS 504 or LED radiation alone. The treated spores were then cultured on potato dextrose agar plates at 25 °C for 3 to 4 days before determination of colony formation as a measure of viability. Fungal growth was inhibited in a manner dependent on both LED energy and TONS 504 concentration. The inhibitory effect on F. solani was complete with TONS 504 at a concentration of 1 mg/L and LED irradiation at 30 J/cm² as well as at a TONS 504 concentration of 10 mg/L and LED irradiation at 10, 20, or 30 J/cm². In contrast, that on A. fumigatus was only partial at a TONS 504 concentration of 10 mg/L and LED irradiation at 20 or 30 J/cm². The antifungal effect of PACT on A. fumigatus was thus inferior to that on F. solani. PACT with TONS 504 and an LED thus warrants further evaluation with regard to its potential effectiveness for the treatment of infectious fungal keratitis.

https://ift.tt/2DYoRS6

Secukinumab for treatment of psoriasis: does secukinumab precipitate or promote the presentation of cutaneous T‐cell lymphoma?

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2RoDAbF

Analysis of BAFF gene polymorphisms in UK Graves’ disease patients

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2Qyl3bR

Relationship between serum level of GDF8, GDF11 and bone mineral density in girls with anorexia nervosa

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2O6v2rS

Scholar : ΠΑΡΕΣΗ BELL - νέα αποτελέσματα

[PDF] Imaging Tryptophan Metabolism in Human Brain Tumors

E Bosnyák - 2018

… with anaplastic astrocytoma and glioblastoma, the most common manifestations are focal
neurological deficit (such as signs of high intracranial pressure, headache, paresis) and
cognitive deficit [Riva et al., 2006; Tanaka et al., 2012]. However, in some cases, the only …

[PDF] HiRUIN--

C I'MIE

Page 1. University of New Mexico UNM Digital Repository Las Vegas Daily Optic,
1896-1907 New Mexico Historical Newspapers 6-26-1906 Las Vegas Daily Optic,
06-26-1906 The Las Vegas Publishing Co. & The People's Paper …

[HTML] Cerebrotendinous Xanthomatosis

AA Expert

… CYP27A1 mutation leads to decreased synthesis of bile acid, excess
production of cholestanol, and consequent accumulation of cholestanol
in tissues, including brain, leading to progressive neurological dysfunction …

 

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Scholar : ΓΛΩΣΣΙΤΙΣ - νέα αποτελέσματα

Acquired Immune Deficiency Syndrome

L Jiang, X Jin, Q Chen - Case Based Oral Mucosal Diseases, 2018

… Case 83 HIV-Associated Median Rhomboid Glossitis. Open image in new window Fig.
8.2. Fig. 8.2 … Diagnosis: HIV-associated median rhomboid glossitis. Diagnosis Basis: 1.
Oral manifestations were suggestive of median rhomboid glossitis. 2 …

Labiolingual Diseases

L Jiang, X Jin, Q Chen - Case Based Oral Mucosal Diseases, 2018

… In addition, specifically systemic treatment should be employed to handle
the possible systemic etiology. 6.3 Geographic Glossitis. Case 67 Geographic
Glossitis (Adult). Open image in new window Fig … Case 68 Geographic …

[PDF] Oral findings, Oxidative Stress and Antioxidant Biomarker Assessment in Serum and Saliva of Crohn's Patients

ZK Abbas, TF Zaidan

… Other nonspecific oral findings such as angular cheilitis, aphthous
ulcerations, glossitis, stomatitis and perioral dermatitis can also seen in
patients with Crohn's disease as a result of pathological process of the …

Oral Mucosal Lesions of Systemic Diseases

X Jin, X Zeng, L Wu - Case Based Oral Mucosal Diseases, 2018

… Allergy: None. Physical Examination: Severe ulcer with an area of 4 × 5 cm
was located on the anterior palate, with no bone damage or perforation by
systemic examination. Atrophic tongue can also be detected (Fig. 10.4) …

Freier Vortrag

S Lindner, F Lang, T Berg, J Riemann, S Ajib… - … für Hämatologie und …, 2018

… gastroösoph. Refluxkrank., Proktalgie, Polyp an Wangenschleimhaut, Zahnfleischbluten,
Glossitis, Parodontose, Zahnerkrank., Brechreiz, Flatulenz, Mundgeruch, Hepatotox.,
Gallenblasendil., Exfoliation der Haut, Urtikaria, Lichtempf …

Oral Hypersensitive Reactive Diseases

Y Zhou, X Jin, Q Chen - Case Based Oral Mucosal Diseases, 2018

… pseudomembrane. One special kind of allergic contact stomatitis is plasma cell
gingivitis, appearing as generalized erythema and edema of the attached gingiva,
occasionally accompanied by cheilitis or glossitis (Fig. 2.9). The …

[HTML] Oxycodon HCl Aurobindo Uses

OHC Aurobindo

… Cardiovascular: deep thrombophlebitis, heart failure, hemorrhage, hypotension, migraine,
palpitation, and tachycardia. Digestive: anorexia, diarrhea, dyspepsia, dysphagia, gingivitis,
glossitis, and nausea and vomiting. Hemic and Lymphatic: anemia and leukopenia …

 

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Scholar : intitle:Bioprinting - νέα αποτελέσματα

Comparative analysis of a new industry: The world of 3D bioprinting

L PANTALEONI - 2018

Il lavoro di tesi ruota attorno alla nascita dell'industria delle bio stampanti 3D. è stato
svolto un lavoro di reperimento di informazoni e di interviste agli utilizzatori per
identificare la fase in cui si trova l'industria in questo preciso momento storico. In oltre …

3D Bioprinting with UVA1 Radiation and Photoinitiator Irgacure 2959: Can the ASTM Standard L929 Cells Predict Human Stem Cell Cytotoxicity?

DE Godar, C Gurunathan, I Ilev - Photochemistry and Photobiology

Abstract 3D bioprinting often involves human mesenchymal stem cells (hMSC) that
are differentiated into the desired cells to replace body parts like ears. Scaffolds of
crosslinked hydrogels offer structural support during differentiation. Different …

 

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Scholar : Obstructive sleep apnea - νέα αποτελέσματα

Endoscopically-Assisted Surgical Expansion (EASE) for the Treatment of Obstructive Sleep Apnea

K Li, S Quo, C Guilleminault - Sleep Medicine, 2018

Objective The aim of this retrospective study was to evaluate the results of an
outpatient surgical procedure named endoscopically-assisted surgical expansion
(EASE) in expanding the maxilla to treat obstructive sleep apnea (OSA) in …

Fundamental Principles of Pediatric Physiology and Anatomy

JN Brownstein - Pediatric Dentistry, 2019

… Versed), ↓ BP, ↓ SVR, ↓ CO, ↑ HR, ↑ RR (at low doses), ↓ RR (at high
doses), ↑ upper airway obstruction, ↓ V T , hypoxic … For airway assessment,
this should specifically include any history of snoring while sleeping …

Race/Ethnicity Concordant Provider

K Railey, M Railey - Diversity and Inclusion in Quality Patient Care, 2019

… Keywords. Race concordance Patient quality Patient satisfaction Provider race/ethnicity
Race/ethnicity Difficult encounter Hypertension Obstructive sleep apnea. Download chapter
PDF … He reports he has a history of hypertension and obstructive sleep apnea (OSA) …

Gay Student

T Layng, J Moll - Diversity and Inclusion in Quality Patient Care, 2019

… Review of Symptoms. Asymptomatic, anxious about the examination. Past Medical History.
Type II diabetes mellitus, hyperlipidemia, obstructive sleep apnea, hypertension. Family
History. Type II diabetes mellitus, coronary artery disease. Social History …

[PDF] TREATMENT COMPLETE DENTURES–AN ALTERNATIVE FOR ALTERED VERTICAL DIMENSION

MK Vijaykrishna - University Journal of Surgery and Surgical Specialities, 2018

… causing decrease in vertical dimension resulting into collapse of orofacial
structures.16Loss of vertical dimension of occlusion which causes reduction
of the lower face height and rotation of the mandible are some of the …

[PDF] Tracheostomy among pediatric patients: A review

SK Swain, A Das, IC Behera, B Bhattacharyya - Indian Journal of Child Health, 2018

… In pediatric patients, common requirement for tracheostomy is congenital
or acquired airway obstruction, neurological conditions … These clinical
conditions are retropharyngeal abscess, epiglottitis, and post-tonsillectomy …

重度 OSAS 患者双侧额叶 1H-MRS 改变与抑郁症之间的相关性研究

赵育英， 毛新峰， 沈小勇， 黄小燕， 姚丽娣， 陆华东 - 中国现代医生, 2018

… 摘要：目的探讨重度阻塞性睡眠呼吸暂停综合征（obstructive sleep apnea
syndrome，OSAS）患者双侧额叶。H-MRS变化及其与抑郁症之间的相关性。
方法采用，H-MRS成像技术检测56例重度OSAS患者（重度OSAS组）与56 …

去乙酰化酶抑制剂 SAHA 对间歇性低氧引起的小鼠心血管损伤的保护作用

沈帆 - 2018

… 沈帆. 【摘要】：背景阻塞性阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)是一种常见病症,
其特征是在睡眠期间发作性上气道变窄导致间歇性低氧(intermittent hypoxia,IH)和睡眠中断,
是多种心血管疾病的独立危险因素。IH与高血压、交感神经活性增加、内皮功能障碍 …

Long-Term Outcomes Among Survivors of Childhood Central Nervous System Malignancies: Late Mortality, Subsequent Neoplasms, Endocrine and Neurologic …

GT Armstrong, RB Khan, W Chemaitilly - Brain Tumors in Children, 2018

According to the most recent estimates from the Surveillance, Epidemiology
and End Results (SEER), 74% of children younger than 20 years of age
diagnosed with a central nervous system (CNS)...

[PDF] Surgical Options In Obstructive Sleep Apnoea

M Gupta, P Mehra, N Gogia

… 1. Selection of the individual procedure is determined by the severity of the
sleep apnea, the presence of a … at the level of nasopharynx and oropharynx
Fujita 2a - obstruction primarily at oropharynx Fujita 2b - obstruction primarily …

 

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