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Πέμπτη 8 Οκτωβρίου 2020

Medicine by Alexandros G. Sfakianakis

Primary sclerosing cholangitis and autoimmune hepatitis
Primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome associated with inflammatory bowel disease: A case report and systematic review.: Primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome associated with inflammatory bowel disease: A case report and systematic review.World J Clin Cases. 2020 Sep 26;8(18):4075-4093Authors: Ballotin VR, Bigarella LG, Riva F, Onzi G, Balbinot RA, Balbinot SS, Soldera JAbstract BACKGROUND: A previously healthy 22-year-old...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:29
Epidermolytic acanthoma: commonly misdiagnosed as condyloma accuminatum, verruca, and seborrheic keratosis
Epidermolytic acanthoma: A case report.: Epidermolytic acanthoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4094-4099Authors: Ginsberg AS, Rajagopalan A, Terlizzi JPAbstract BACKGROUND: Epidermolytic acanthoma (EA) is a rare benign skin lesion, usually found in the genital area of men and women, with epidermolytic hyperkeratosis as its distinguishing histologic characteristic. It is commonly misdiagnosed as condyloma accuminatum, verruca, and seborrheic keratosis. Since this lesion...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:28
Management of pembrolizumab-induced steroid refractory mucositis with infliximab...........................Η ινφλιξιμάμπη (infliximab) είναι ένα χιμαιρικό μονοκλωνικό αντίσωμα ανθρώπου-ποντικού που συνδέεται με μεγάλη χημική συγγένεια και με τους διαλυτούς και με τους διαμεμβρανικούς τύπους του TNFα (παράγοντα νέκρωσης των όγκων άλφα), αλλά όχι με τη λεμφοτοξίνη α (TNFβ). Ανατομική/θεραπευτική/χημική (ATC) ταξινόμηση Κωδικός Τίτλος Κατηγοριοποίηση L04AB02 Infliximab L Αντινεοπλασματικοί και ανοσοτροποποιητικοί παράγοντες → L04 Ανοσοκατασταλτικοί παράγοντες → L04A Ανοσοκατασταλτικοί παράγοντες → L04AB Αναστολείς του παράγοντα νέκρωσης όγκων α (TNF-α) Πηγή: Γαληνός Οδηγός Φαρμάκων
Management of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report.: Management of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report.World J Clin Cases. 2020 Sep 26;8(18):4100-4108Authors: Dang H, Sun J, Wang G, Renner G, Layfield L, Hilli JAbstract BACKGROUND: Pembrolizumab is an anti-programmed death receptor 1 (PD-1) that was shown to have a tolerable safety profile with 17% of grade 3-4 drug-related adverse events, notable...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:26
Small bowel obstruction caused by a bezoar
Small bowel obstruction caused by a bezoar following an adult simultaneous liver-kidney transplantation: A case report.: Small bowel obstruction caused by a bezoar following an adult simultaneous liver-kidney transplantation: A case report.World J Clin Cases. 2020 Sep 26;8(18):4109-4113Authors: Pan G, Kim RD, Campsen J, Rofaiel GAbstract BACKGROUND: Small bowel obstructions (SBOs) are common following a large intra-abdominal operation; however, SBOs caused by bezoars are unreported in patients...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:24
Laparoscopic resection of primary retroperitoneal schwannoma
Laparoscopic resection of primary retroperitoneal schwannoma: A case report.: Laparoscopic resection of primary retroperitoneal schwannoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4114-4121Authors: Ribeiro MA, Elias YG, Augusto SS, Néder PR, Costa CT, Maurício AD, Sampaio AP, Fonseca AZAbstract BACKGROUND: Schwannomas are rare, often benign, tumors deriving from Schwann cells that have low incidence in the retroperitoneal region (0.5% to 5%). Their diagnosis is hardly confirmed...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:24
Acute febrile neutrophilic dermatosis - Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma
Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma: A case report.: Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4122-4127Authors: Lemaire CC, Portilho ALC, Pinheiro LV, Vivas RA, Britto M, Montenegro M, Rodrigues LFF, Arruda S, Lyra AC, Cavalcante LNAbstract BACKGROUND: Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare skin disorder that may be associated with...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:22
Milk-aspiration
Multidisciplinary approach to suspected sudden unexpected infant death caused by milk-aspiration: A case report.: Multidisciplinary approach to suspected sudden unexpected infant death caused by milk-aspiration: A case report.World J Clin Cases. 2020 Sep 26;8(18):4128-4134Authors: Maiese A, La Russa R, Arcangeli M, Volonnino G, De Matteis A, Frati P, Fineschi VAbstract BACKGROUND: The term sudden unexpected infant death (SUID) is not always properly invoked. It refers to a broad range of...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:20
Stress fractures in the calcaneus, intermediate cuneiform bone, sacrum, tibia (bilateral), navicular bone and femoral neck
Stress fractures in uncommon location: Six case reports and review of the literature.: Stress fractures in uncommon location: Six case reports and review of the literature.World J Clin Cases. 2020 Sep 26;8(18):4135-4150Authors: Ficek K, Cyganik P, Rajca J, Racut A, Kiełtyka A, Grzywocz J, Hajduk GAbstract BACKGROUND: Individuals' interest in sports activities has been increasing, contributing to more stress fracture occurrences in uncommon locations on the skeleton. In this study, several...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:20
Celiac disease and Sjögren's syndrome
Celiac disease and Sjögren's syndrome: A case report and review of literature.: Celiac disease and Sjögren's syndrome: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4151-4161Authors: Balaban DV, Mihai A, Dima A, Popp A, Jinga M, Jurcut CAbstract BACKGROUND: Celiac disease (CD) is a systemic, chronic immune-mediated disease triggered by gluten ingestion in genetically-susceptible individuals, with a prevalence of 1% worldwide. Sjogren's syndrome (SS) is also...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:19
Adverse reaction to mesalazine: Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient
Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient - a putative adverse reaction to mesalazine: A case report and review of literature.: Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient - a putative adverse reaction to mesalazine: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4162-4168Authors: Cernomaz AT, Bordeianu G, Terinte C, Gavrilescu CMAbstract BACKGROUND: Lung and airway involvement in inflammatory bowel disease...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:18
Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.
Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.: Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.World J Clin Cases. 2020 Sep 26;8(18):4169-4176Authors: Prídavková D, Samoš M, Kyčina R, Adamicová K, Kalman M, Belicová M, Mokáň MAbstract BACKGROUND: Insulinomas are the most common type of functioning endocrine neoplasms of the pancreas presenting hypoglycemic symptoms. Patients characteristically...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:17
Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.
Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.: Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.World J Clin Cases. 2020 Sep 26;8(18):4177-4185Authors: Nomura E, Kayano H, Machida T, Izumi H, Yamamoto S, Sugawara A, Mukai M, Hasebe TAbstract BACKGROUND: Neoadjuvant chemoradiotherapy (NACRT) has not been accepted as a general therapy for gastric cancer...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:17
Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.
Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.: Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.World J Clin Cases. 2020 Sep 26;8(18):4186-4192Authors: Lee JH, Jang HJ, Park JH, Kim HK, Lee S, Kim JY, Kim SHAbstract BACKGROUND: Pleuroparenchymal fibroelastosis (PPFE) is a rare idiopathic interstitial pneumonia characterized by predominantly upper lobe involvement...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:16
Superior mesenteric vein thrombosis induced by influenza infection
Superior mesenteric vein thrombosis induced by influenza infection: A case report.: Superior mesenteric vein thrombosis induced by influenza infection: A case report.World J Clin Cases. 2020 Sep 26;8(18):4193-4199Authors: Oh GM, Jung K, Kim JH, Kim SE, Moon W, Park MI, Park SJAbstract BACKGROUND: Among the various types and causes of mesenteric ischemia, superior mesenteric vein (SMV) thrombosis is a rare and ambiguous disease. If a patient presents with SMV thrombosis, past medical history...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:14
Mucinous adenocarcinoma of the buttock associated with hidradenitis
Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report.: Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report.World J Clin Cases. 2020 Sep 26;8(18):4200-4206Authors: Kim SJ, Kim TG, Gu MJ, Kim SAbstract BACKGROUND: Mucinous adenocarcinomas of the buttock are rare and have an uncertain etiology and natural course. They are usually related to chronic anal fistulas, hidradenitis suppurativa, or Crohn's disease. Here, we report a case...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:14
Perivascular epithelioid cell tumor (PEComa) : TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery
TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery: A case report and review of literature.: TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4207-4214Authors: Kim NI, Lee JS, Choi YD, Ju UC, Nam JHAbstract BACKGROUND: Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor that exhibits an epithelioid and spindle cell morphology. The tumor...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:12
Robotic surgery in giant multilocular cystadenoma of the prostate
Robotic surgery in giant multilocular cystadenoma of the prostate: A rare case report.: Robotic surgery in giant multilocular cystadenoma of the prostate: A rare case report.World J Clin Cases. 2020 Sep 26;8(18):4215-4222Authors: Fan LW, Chang YH, Shao IH, Wu KF, Pang STAbstract BACKGROUND: Giant multilocular cystadenoma (GMC) of the prostate gland is a very rare benign tumor. Although the benign nature has been known, complete surgical excision is the major treatment consensus because...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:11
Multiple recurrent neurofibromas in the abdominal wall:
Multiple recurrent neurofibromas in the abdominal wall: A case report.: Multiple recurrent neurofibromas in the abdominal wall: A case report.World J Clin Cases. 2020 Sep 26;8(18):4223-4227Authors: Zhao XF, Shen YM, Chen JAbstract BACKGROUND: Neurofibroma can be a clinical manifestation of neurofibromatosis, which is a benign neurogenic tumor that occurs sporadically. Neurofibromas in the abdomen usually appear in the retroperitoneal space. Reports on neurofibromas in the abdominal wall...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:11
Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.
Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.: Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.World J Clin Cases. 2020 Sep 26;8(18):4228-4233Authors: Chen K, Lan YZ, Li J, Xiang YY, Zeng DZAbstract BACKGROUND: A pelvic floor hernia is defined as a pelvic floor defect through which the intraabdominal viscera may protrude. It is an infrequent complication...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:10
Encrusted cystitis (EC) is a chronic inflammation of the bladder associated with mucosal encrustations. Bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into the bladder submucosal tissue can be used for treatment of EC.
Successful treatment of encrusted cystitis: A case report and review of literature.: Successful treatment of encrusted cystitis: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4234-4244Authors: Fu JG, Xie KJAbstract BACKGROUND: Encrusted cystitis (EC) is a chronic inflammation of the bladder associated with mucosal encrustations. Early diagnosis and optimal treatment are not well established. Here, we report a case of EC successfully treated with com-bination...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:09
Massive pulmonary haemorrhage due to severe trauma
Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report.: Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report.World J Clin Cases. 2020 Sep 26;8(18):4245-4251Authors: Zhang BY, Chen XC, You Y, Chen M, Yu WKAbstract BACKGROUND: Massive pulmonary haemorrhage can spoil the entire lung and block...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:08
Gitelman syndrome ... hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria
Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report.: Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report.World J Clin Cases. 2020 Sep 26;8(18):4252-4258Authors: Yu RZ, Chen MSAbstract BACKGROUND: Gitelman syndrome (GS) is an unusual, autosomal recessive salt-losing tubulopathy characterized by hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria. It is caused by mutations in the solute carrier family...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:08
Arterial embolism caused by a peripherally inserted central catheter in a very premature infant:
Arterial embolism caused by a peripherally inserted central catheter in a very premature infant: A case report and literature review.: Arterial embolism caused by a peripherally inserted central catheter in a very premature infant: A case report and literature review.World J Clin Cases. 2020 Sep 26;8(18):4259-4265Authors: Huang YF, Hu YL, Wan XL, Cheng H, Wu YH, Yang XY, Shi JAbstract BACKGROUND: Extremely premature infants have poor vascular conditions. Operators often choose deep veins...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:07
Left bundle branch pacing with optimization of cardiac resynchronization treatment
Left bundle branch pacing with optimization of cardiac resynchronization treatment: A case report.: Left bundle branch pacing with optimization of cardiac resynchronization treatment: A case report.World J Clin Cases. 2020 Sep 26;8(18):4266-4271Authors: Zhang DH, Lang MJ, Tang G, Chen XX, Li HFAbstract BACKGROUND: Cardiac resynchronization therapy (CRT) is a well-established therapy for patients with cardiomyopathy. CASE SUMMARY: The patient underwent left bundle branch area and...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:07
Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature
Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.: Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.World J Clin Cases. 2020 Sep 26;8(18):4272-4279Authors: Gu KC, Wan Y, Xiang L, Wang LS, Yao WJAbstract BACKGROUND: Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of meningioma and is classified as grade I (benign) tumor. It is characterized by abundant infiltrates of lymphocytes and plasma cells. Here,...
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης
07:06
Peripheral Photopenia on Whole-Body PET/CT Imaging With 18F-FDG in Patients With Compartment Syndrome and Mesenteric Venous Thrombosis
Peripheral Photopenia on Whole-Body PET/CT Imaging With 18F-FDG in Patients With Compartment Syndrome and Mesenteric Venous Thrombosis: We present 2 cases that demonstrate photopenia in peripheral areas on whole-body PET/CT imaging with 18F-FDG as a sign of absent perfusion with severe short-term complications. The scan of the first patient shows photopenia in the right ankle and foot, resulting from compartment syndrome, caused by hemolytic group A streptococcus bacteremia with endocarditis and...
Αλέξανδρος Γ. Σφακιανάκης
08:17
Maxillary Sinus Cholesterol Granuloma Showing FDG Uptake on PET/CT
An Unusual Case of Maxillary Sinus Cholesterol Granuloma Showing FDG Uptake on PET/CT: Cholesterol granuloma (CG) occurs primarily in the middle ear and rarely in the paranasal sinus. We report an unusual case of paranasal sinus CG with 18F-FDG uptake. A 76-year-old man presented with right refractory epistaxis. PET/CT showed FDG uptake in the maxillary sinus. CT findings are typically uncharacteristic, whereas MRI scans are characterized by a high signal on both T1-weighted and T2-weighted images....
Αλέξανδρος Γ. Σφακιανάκης
08:16
fever, cutaneous erythematous plaques, and aseptic neutrophilic infiltration of various organs........................Evaluation of the Therapeutic Response by 11C-Methionine PET in a Case of Neuro-Sweet Disease
Evaluation of the Therapeutic Response by 11C-Methionine PET in a Case of Neuro-Sweet Disease: Sweet disease is a multisystem inflammatory disorder characterized by fever, cutaneous erythematous plaques, and aseptic neutrophilic infiltration of various organs. Neuro-Sweet disease is a known rare central nervous system complication of Sweet disease. A 67-year-old Japanese woman who was diagnosed with neuro-Sweet disease underwent 11C-methionine (11C-MET) PET. 11C-MET PET revealed increased accumulation...
Αλέξανδρος Γ. Σφακιανάκης
08:16
Humongous Seminal Vesicles on 68Ga-DOTATOC PET/CT: A Rare Presentation of a Neuroendocrine Tumor
Humongous Seminal Vesicles on 68Ga-DOTATOC PET/CT: A Rare Presentation of a Neuroendocrine Tumor: A 24-year-old man presented with decreased appetite, fatigue, abdominal pain, and acute renal insufficiency. Ultrasound showed bilateral hydronephrosis. CT of the abdomen revealed enlarged seminal vesicles causing bilateral hydronephrosis, mesenteric and peritoneal metastases, liver lesions, and enlarged lymph nodes in the retroperitoneum. A biopsy from a peritoneal lesion demonstrated metastasis of...
Αλέξανδρος Γ. Σφακιανάκης
08:15
99mTc-Mebrofenin SPECT/CT in Hepatic Infarction
99mTc-Mebrofenin SPECT/CT in Hepatic Infarction: A 68-year-old man with hereditary hypercoagulability was referred to nuclear medicine for elevated aminotransferases after a recent living-donor liver transplant. A hepatic infarction was suspected. A 99mTc-mebrofenin SPECT/CT was performed and showed decreased radiotracer uptake in a wedge-shaped distribution in the anterior liver suggestive of a hepatic infarction. Subsequently, an enhanced MRI corroborated the diagnosis. Oral anticoagulation therapy...
Αλέξανδρος Γ. Σφακιανάκης
08:15
Maximum Uptake and Hypermetabolic Volume of 18F-FDOPA PET Estimate Molecular Status and Overall Survival in Low-Grade Gliomas: A PET and MRI Study
Maximum Uptake and Hypermetabolic Volume of 18F-FDOPA PET Estimate Molecular Status and Overall Survival in Low-Grade Gliomas: A PET and MRI Study: Purpose We evaluated 18F-FDOPA PET and MRI characteristics in association with the molecular status and overall survival (OS) in a large number of low-grade gliomas (LGGs). Methods Eighty-six patients who underwent 18F-FDOPA PET and MRI and were diagnosed with new or recurrent LGGs were retrospectively evaluated with respect to their isocitrate...
Αλέξανδρος Γ. Σφακιανάκης
08:14
Is 68Ga–Prostate-Specific Membrane Antigen PET/CT Superior than 18F-FDG PET/CT for Evaluation of Metastatic Osteosarcoma?
Is 68Ga–Prostate-Specific Membrane Antigen PET/CT Superior than 18F-FDG PET/CT for Evaluation of Metastatic Osteosarcoma?: We present the case of a 75-year-old man with osteosarcoma of the sternum in whom 68Ga-prostate-specific membrane antigen (PSMA) PET/CT showed high radiotracer activity in the primary tumor and metastatic lesions than 18F-FDG PET/CT. The present case shows that 68Ga-PSMA PET/CT is very useful for staging of osteosarcoma due to in vivo expression of PSMA. 68Ga-PSMA PET/CT can...
Αλέξανδρος Γ. Σφακιανάκης
08:14
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm: AbstractCytokine storm can result from cancer immunotherapy or certain infections, including COVID-19. Though short-term immune-related adverse events are routinely described, longer-term immune consequences and sequential immune monitoring are not as well defined. In 2006, six healthy volunteers received TGN1412, a CD28 superagonist antibody, in a first-in-man clinical trial and suffered from...
Αλέξανδρος Γ. Σφακιανάκης
08:13
The role of mitophagy in the mechanism of genioglossal dysfunction caused by chronic intermittent hypoxia and the protective effect of adiponectin
The role of mitophagy in the mechanism of genioglossal dysfunction caused by chronic intermittent hypoxia and the protective effect of adiponectin: AbstractPurposeDysfunction of the genioglossus muscle is important in the pathogenesis of obstructive sleep apnea due to chronic intermittent hypoxia (CIH). Mitochondrial impairment resulting from hypoxia is mitigated by mitophagy to avoid cell apoptosis in cardiomyocytes. This project was designed to explore the effects of CIH on mitophagy in the genioglossus...
Αλέξανδρος Γ. Σφακιανάκης
08:13
Cutis Marmorata Telangiectatica Congenita Associated with Hemiatrophy
Cutis Marmorata Telangiectatica Congenita Associated with Hemiatrophy: Cutis marmorata telangiectatica congenita is characterized by the presence of a bluish-purple reticulated cutaneous vascular network on the skin intermixed with telangiectasia and occasionally prominent veins at birth. Areas of the skin within the reticulated cutaneous vascular network may be normal, erythematous, atrophic, and, at times, ulcerated. Areas of ulcerations and focal cutaneous and subcutaneous atrophy occasionally...
Αλέξανδρος Γ. Σφακιανάκης
08:12
Laser‐Induced Differentiation of Human Adipose‐Derived Stem Cells to Temporomandibular Joint Disc Cells
Laser‐Induced Differentiation of Human Adipose‐Derived Stem Cells to Temporomandibular Joint Disc Cells: Background and ObjectivesTemporomandibular disorder (TMD) is an incapacitating disease with temporomandibular joint (TMJ) disc degenerative changes in patients. Despite several research attempts to find a definitive treatment, there is no evidence of a permanent solution. The objective of the current study was to observe the role of 660 nm diode laser in the differentiation of human adipose‐derived...
Αλέξανδρος Γ. Σφακιανάκης
08:11
Temporomandibular joint reconstruction with medial femoral condyle osseocartilaginous flap: a case series
Temporomandibular joint reconstruction with medial femoral condyle osseocartilaginous flap: a case series: Reconstruction for large-scale temporomandibular joint (TMJ) defects can be challenging. We have used the medial femoral condyle (MFC) osseocartilaginous flap for repair of TMJ defects. The aim of this paper was to describe our technique and to present the preliminary results. The MFC osseocartilaginous flap was used as a free vascularized graft for TMJ defect in four patients who had undergone...
Αλέξανδρος Γ. Σφακιανάκης
08:11
Promethazine hydrochloride injection in the sclerotherapy of oral mucocele
Preliminary experience with promethazine hydrochloride injection in the sclerotherapy of oral mucocele: In this study, we took advantage of the corrosiveness of promethazine hydrochloride injection, i.e., its chemical corrosiveness at the injection site, for sclerotherapy of mucocele1. In previous reports, the more serious complications may have been caused by perivascular extravasation or unintentional intra-arterial injection, which is a common feature of all chemical corrosive sclerosants2. Therefore,...
Αλέξανδρος Γ. Σφακιανάκης
08:10
Children with Fontan circulation are at risk of developing hepatic fibrosis/cirrhosis.....................Hepatic magnetic resonance T1-mapping and extracellular volume fraction compared to shear-wave elastography in pediatric Fontan-associated liver disease
Hepatic magnetic resonance T1-mapping and extracellular volume fraction compared to shear-wave elastography in pediatric Fontan-associated liver disease: AbstractBackgroundChildren with Fontan circulation are at risk of developing hepatic fibrosis/cirrhosis. Reliable noninvasive monitoring techniques are lacking or under development. ObjectiveTo investigate surrogate indicators of hepatic fibrosis in adolescents with Fontan circulation by evaluating hepatic magnetic resonance...
Αλέξανδρος Γ. Σφακιανάκης
08:09
Should not we be using aspirin in patients with a ventriculoatrial shunt?
Should not we be using aspirin in patients with a ventriculoatrial shunt? Borrowing a leaf from other specialities: a case for surrogate evidence: AbstractIntroductionVentriculoatrial (VA) shunts are life-saving in circumstances where ventriculoperitoneal shunts (VP) have failed. They are at risk for different complications, and more specific of them are cardiopulmonary complications. Currently, there are no standard recommendations concerning screening for risk factors, prophylaxis, or anticoagulation...
Αλέξανδρος Γ. Σφακιανάκης
08:09
The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea
The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea: AbstractPurposeObstructive sleep apnea (OSA) is a disorder characterized by recurrent episodes of obstruction of the upper respiratory tract during sleep often accompanied by oxygen desaturations. Antioxidant defense mechanisms are important to prevent OSA-associated diseases and decrease mortality. We aimed to determine the levels of selenium and vitamins A, C, and E in patients with OSA but without any comorbidities...
Αλέξανδρος Γ. Σφακιανάκης
08:08
Combination therapies utilizing neoepitope-targeted vaccines
Combination therapies utilizing neoepitope-targeted vaccines: AbstractClinical successes have been achieved with checkpoint blockade therapy, which facilitates the function of T cells recognizing tumor-specific mutations known as neoepitopes. It is a reasonable hypothesis that therapeutic cancer vaccines targeting neoepitopes uniquely expressed by a patient's tumor would prove to be an effective therapeutic strategy. With the advent of high-throughput next generation sequencing, it is now possible...
Αλέξανδρος Γ. Σφακιανάκης
08:08
Evaluation of the Physiological Changes in the Central Airway on Multi-Detector Computed Tomography
Evaluation of the Physiological Changes in the Central Airway on Multi-Detector Computed Tomography: Background: Most data about the trachea are collected during deep inspiration breath holding (DIBH) using multi-detector computed tomography (MDCT). Images of the physiological changes in the central airway are lacking. Objective: The aim of this study was to explore the physiological changes in the central airway on MDCT during DIBH and deep expiration breath holding (DEBH). Method: The data from...
Αλέξανδρος Γ. Σφακιανάκης
08:07
"J Drugs Dermatol"[jour];
"J Drugs Dermatol"[jour];1J Drugs Dermatol. 2020 Sep 1;19(9):889-892. doi: 10.36849/JDD.2020.10.36849/JDD.2020.5323.Systemic Medications of Dermatological Importance in COVID-19Robert A Schwartz, Aseem Sharma, Jacek C Szepietowski, Sunmeet Sandhu, Mohamad GoldustPMID: 33026746 DOI: 10.36849/JDD.2020.10.36849/JDD.2020.5323AbstractEarly December 2019 witnessed an international outbreak of a novel coronavirus (COVID 19) designated severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). Since then,...
Αλέξανδρος Γ. Σφακιανάκης
08:06
Identification of Serum CMTM2 as a Potential Biomarker for HBV-Related Disorders
Identification of Serum CMTM2 as a Potential Biomarker for HBV-Related Disorders: Substantial advance supports that CMTM2 serve as an important performer in physiological and pathological processes. However, very little is clear about the relationship between CMTM2 and HBV-related disorders. Here, for the first time, we explore that whether or not serum CMTM2 is involved in HBV-related diseases. We found that CMTM2 values were significantly lower in patients compared to healthy control (p 
Αλέξανδρος Γ. Σφακιανάκης
08:02
Technical nuances of a posterior-only L5 vertebrectomy with anterior column reconstruction
Technical nuances of a posterior-only L5 vertebrectomy with anterior column reconstruction: Technical nuances of a posterior-only L5 vertebrectomy with anterior column reconstruction Category: Article Type: Lukasz Bogdan1, Michael Galgano2Medical Student, St. George's University, School of Medicine, St. Gerorge's, West Indies, Grenada,Department of Neurosurgery, SUNY Upstate Medical University, Syracuse, New York, United States.Correspondence Address:Michael GalganoDepartment of Neurosurgery, SUNY...
Αλέξανδρος Γ. Σφακιανάκης
08:02
Late-onset occlusion of the Monro foramina after endoscopic third ventriculostomy in adults
Late-onset occlusion of the Monro foramina after endoscopic third ventriculostomy in adults: Case discussion and review of the literature: Late-onset occlusion of the Monro foramina after endoscopic third ventriculostomy in adults: Case discussion and review of the literature Category: Article Type: Sara Fabbro, Francesco Tuniz, Daniele Piccolo, Antonio CramaroDepartment of Neurosurgery, ASUFC Santa Maria della Misericordia, Piazzale Santa Maria della Misericordia, Udine, Italy.DOI:10.25259/SNI_519_2020Copyright:...
Αλέξανδρος Γ. Σφακιανάκης
08:01
Spinal cord herniation following multilevel anterior cervical discectomy and fusion
Spinal cord herniation following multilevel anterior cervical discectomy and fusion: A case report and literature review: Spinal cord herniation following multilevel anterior cervical discectomy and fusion: A case report and literature review Category: Article Type: Siddharth Sinha, K. Joshi GeorgeDepartment of Neurosurgery, Salford Royal Foundation Trust, Salford Royal Foundation Trust, Stott Lane Manchester, Greater Manchester, United Kingdom.DOI:10.25259/SNI_508_2020Copyright: © 2020 Surgical...
Αλέξανδρος Γ. Σφακιανάκης
08:00
The relationship between vascular endothelial growth factor and histological grade in intracranial meningioma
The relationship between vascular endothelial growth factor and histological grade in intracranial meningioma: The relationship between vascular endothelial growth factor and histological grade in intracranial meningioma Category: Article Type: Rafael Contage Winter1, Apio Claudio Martins Antunes2, Francine Hehn de Oliveira3Departments of Neurosurgery Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.Departments of Neurosurgery Hospital de Clínicas de Porto Alegre,...
Αλέξανδρος Γ. Σφακιανάκης
08:00
Whiplash cervical trauma with fracture and migration of carotid stent fragments
"Whiplash" cervical trauma with fracture and migration of carotid stent fragments: "Whiplash" cervical trauma with fracture and migration of carotid stent fragments Category: Article Type: Danilo Almeida Silva, Guilherme Brasileiro de Aguiar, Maurício Jory, Mario Luiz Marques Conti, José Carlos Esteves VeigaDepartment of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesário Motta Júnior, São Paulo, Brazil.DOI:10.25259/SNI_550_2020Copyright: © 2020 Surgical Neurology International...
Αλέξανδρος Γ. Σφακιανάκης
07:59
Fusiform superior cerebellar artery aneurysm treated with flow diversion: A case report
Fusiform superior cerebellar artery aneurysm treated with flow diversion: A case report: Fusiform superior cerebellar artery aneurysm treated with flow diversion: A case report Category: Article Type: Yafell Serulle, Deepak Khatri, Jada Fletcher, Anna Pappas, Audrey Heidbreder, David Langer, Rafael A. OrtizDepartment of Neurosurgery, Lenox Hill Hospital, New York, United States.DOI:10.25259/SNI_556_2020Copyright: © 2020 Surgical Neurology International This is an open-access article distributed under...
Αλέξανδρος Γ. Σφακιανάκης
07:59
Lumbosacral extradural extramedullary hematopoiesis in thalassemia major causing spinal canal stenosis
Lumbosacral extradural extramedullary hematopoiesis in thalassemia major causing spinal canal stenosis: Lumbosacral extradural extramedullary hematopoiesis in thalassemia major causing spinal canal stenosis Category: Article Type: Sumatha Channapatna Suresh1, Bharath Raju2, Fareed Jumah2, Anil Nanda2Department of Rheumatology, St. John's Medical College and Hospital, Bengaluru, Karnataka, India,Department of Neurosurgery, Rutgers Robert Wood Johnson University Hospital, New Brunswick, New Jersey,...
Αλέξανδρος Γ. Σφακιανάκης
07:58
Atypical delayed presentation of cervical spinal epidural abscess
Case report (precis): Atypical delayed presentation of cervical spinal epidural abscess: Case report (precis): Atypical delayed presentation of cervical spinal epidural abscess Category: Article Type: Nancy E. EpsteinClinical Professor of Neurological Surgery, School of Medicine, State University of NY at Stony Brook, New York, United States.DOI:10.25259/SNI_603_2020Copyright: © 2020 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons...
Αλέξανδρος Γ. Σφακιανάκης
07:58
Traumatic acute epidural hematoma caused by injury of the diploic channels
Traumatic acute epidural hematoma caused by injury of the diploic channels: Traumatic acute epidural hematoma caused by injury of the diploic channels Category: Article Type: Shinichiro Teramoto, Satoshi Tsutsumi, Hisato IshiiDepartment of Neurological Surgery, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.DOI:10.25259/SNI_605_2020Copyright: © 2020 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share...
Αλέξανδρος Γ. Σφακιανάκης
07:57
5-aminolevulinic acid-guided surgery for focal pediatric brainstem gliomas
5-aminolevulinic acid-guided surgery for focal pediatric brainstem gliomas: A preliminary study: 5-aminolevulinic acid-guided surgery for focal pediatric brainstem gliomas: A preliminary study Category: Article Type: Jason LabuschagneDepartment of Paediatric Neurosurgery, Nelson Mandela Childrens Hospital, Parktown, Johanessburg, South Africa.DOI:10.25259/SNI_246_2020Copyright: © 2020 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons...
Αλέξανδρος Γ. Σφακιανάκης
07:55
Alteration of gut microbiota with rifampicin does not impair maternal care
Alteration of gut microbiota with rifampicin does not impair maternal care in the European earwig [NEW RESULTS]: The microbes residing within the gut of an animal host often maximise their own fitness by modifying their host's physiological, reproductive, and behavioural functions. Whereas recent studies suggest that they may also shape host sociality and therefore have critical effects on animal social evolution, the impact of the gut microbiota on maternal care remains unexplored. This is surprising,...
Αλέξανδρος Γ. Σφακιανάκης
07:54
Repurposing of a thromboxane receptor inhibitor
Repurposing of a thromboxane receptor inhibitor based on a novel role in metastasis identified by Phenome Wide Association Study: While new drug discoveries are revolutionizing cancer treatments, repurposing existing drugs would accelerate the timeline and lower the cost for bringing treatments to cancer patients. Our goal was to repurpose CPI211, a potent and selective antagonist of the thromboxane A2-prostanoid receptor (TPr), a G-protein coupled receptor that regulates coagulation, blood pressure,...
Αλέξανδρος Γ. Σφακιανάκης
07:53
Chronic nonbacterial osteomyelitis
Chronic nonbacterial osteomyelitis — clinical and magnetic resonance imaging features: AbstractBackgroundChronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder. Little information exists on the use of imaging techniques in CNO. Materials and methodsWe retrospectively reviewed clinical and MRI findings in children diagnosed with CNO between 2012 and 2018. Criteria for CNO included unifocal or multifocal inflammatory bone lesions, symptom duration >6 weeks...
Αλέξανδρος Γ. Σφακιανάκης
07:53
Maximum AmbiGuity Distance for Phase Imaging in Detection of Traumatic Cerebral Microbleeds
Maximum AmbiGuity Distance for Phase Imaging in Detection of Traumatic Cerebral Microbleeds: An Improvement over Current Imaging Practice [FUNCTIONAL]: BACKGROUND AND PURPOSE:Developed using a rigorous mathematic framework, Maximum AmbiGuity distance for Phase Imaging (MAGPI) is a promising phase-imaging technique that provides optimal phase SNR and reduced susceptibility artifacts. We aimed to test the potential of MAGPI over routinely used SWI in the detection of traumatic cerebral microbleeds...
Αλέξανδρος Γ. Σφακιανάκης
07:51
Characterization of MR Imaging-Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T [PEDIATRICS]
Characterization of MR Imaging-Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T [PEDIATRICS]: BACKGROUND AND PURPOSE:Perivascular spaces play a role in cerebral waste removal and neuroinflammation. Our aim was to provide data regarding the burden of MR imaging–visible perivascular spaces in white matter in healthy adolescents using an automated segmentation method and to establish relationships between common demographic characteristics and perivascular space burden.MATERIALS...
Αλέξανδρος Γ. Σφακιανάκης
07:51
Sensitive Detection of Infratentorial and Upper Cervical Cord Lesions in Multiple Sclerosis with Combined 3D FLAIR and T2-Weighted (FLAIR3) Imaging [ADULT BRAIN]
Sensitive Detection of Infratentorial and Upper Cervical Cord Lesions in Multiple Sclerosis with Combined 3D FLAIR and T2-Weighted (FLAIR3) Imaging [ADULT BRAIN]: BACKGROUND AND PURPOSE:Infratentorial and spinal cord lesions are important for diagnosing and monitoring multiple sclerosis, but they are difficult to detect on conventional MR imaging. We sought to improve the detection of infratentorial and upper cervical cord lesions using composite FLAIR3 images.MATERIALS AND METHODS:3D T2-weighted...
Αλέξανδρος Γ. Σφακιανάκης
07:50
MR Imaging Features of Middle Cranial Fossa Encephaloceles and Their Associations with Epilepsy [ADULT BRAIN]
MR Imaging Features of Middle Cranial Fossa Encephaloceles and Their Associations with Epilepsy [ADULT BRAIN]: BACKGROUND AND PURPOSE:Middle cranial fossa encephaloceles are an increasingly recognized cause of epilepsy; however, they are also often encountered on neuroimaging in patients with no history of seizure. We characterized the MR imaging features of middle cranial fossa encephaloceles in seizure and nonseizure groups with the hope of uncovering features predictive of epileptogenicity.MATERIALS...
Αλέξανδρος Γ. Σφακιανάκης
07:50
Cauda Equina (lumbosacral and coccygeal radicular nerves) and Filum Terminale Arteriovenous Fistulas
Cauda Equina and Filum Terminale Arteriovenous Fistulas: Anatomic and Radiographic Features [SPINE]: SUMMARY:Intradural AVF below the conus medullaris may develop either on the filum terminale or the cauda equina (lumbosacral and coccygeal radicular nerves). Although not a few filum terminale AVFs are found in the literature, only 3 detailed cauda equina AVFs have been reported. Here, we analyze the angiographic and MR imaging findings of our cauda equina and filum terminale AVF cases, supplemented...
Αλέξανδρος Γ. Σφακιανάκης
07:49
Treatment of Acute Ischemic Stroke.....Cangrelor in Cervical and Intracranial Stenting
Use of Cangrelor in Cervical and Intracranial Stenting for the Treatment of Acute Ischemic Stroke: A "Real Life" Single-Center Experience [INTERVENTIONAL]: BACKGROUND AND PURPOSE:In cases of large-vessel-occlusion strokes due to an underlying tandem internal carotid artery occlusion or intracranial atherosclerotic disease, concomitant stent placement may be needed. Immediate platelet inhibition is necessary, but to date, a standardized approach for antiplatelet inhibition in acute settings is still...
Αλέξανδρος Γ. Σφακιανάκης
07:48
Autoimmune Keratitis after Atezolizumab Treatment
Autoimmune Keratitis after Atezolizumab Treatment:
Αλέξανδρος Γ. Σφακιανάκης
07:45
Homotype-Targeted Biogenic Nanoparticles to Kill Multidrug-Resistant Cancer Cells
Pharmaceutics, Vol. 12, Pages 950: Homotype-Targeted Biogenic Nanoparticles to Kill Multidrug-Resistant Cancer Cells: Pharmaceutics, Vol. 12, Pages 950: Homotype-Targeted Biogenic Nanoparticles to Kill Multidrug-Resistant Cancer CellsPharmaceutics doi: 10.3390/pharmaceutics12100950Authors: Imran Shair Mohammad Birendra Chaurasiya Xuan Yang Chuchu Lin Hehui Rong Wei He "Off-targeting" and receptor density expressed at the target sites always compromise the efficacy of the nanoparticle-based...
Αλέξανδρος Γ. Σφακιανάκης
07:41
Mixed infection of hepatic cystic and alveolar echinococcosis
Diagnosis and treatment of mixed infection of hepatic cystic and alveolar echinococcosis: Four case reports.: Related ArticlesDiagnosis and treatment of mixed infection of hepatic cystic and alveolar echinococcosis: Four case reports.World J Clin Cases. 2020 Sep 06;8(17):3911-3919Authors: A JD, Chai JP, Wang H, Gao W, Peng Z, Zhao SY, A XRAbstract BACKGROUND: Mixed infection of hepatic cystic and alveolar echinococcosis is extremely rare. This article reveals the typical imaging manifestations...
Αλέξανδρος Γ. Σφακιανάκης
07:41
Application of artificial neural networks in detection and diagnosis of gastrointestinal and liver tumors.
Application of artificial neural networks in detection and diagnosis of gastrointestinal and liver tumors.: Application of artificial neural networks in detection and diagnosis of gastrointestinal and liver tumors.World J Clin Cases. 2020 Sep 26;8(18):3971-3977Authors: Mao WB, Lyu JY, Vaishnani DK, Lyu YM, Gong W, Xue XL, Shentu YP, Ma JAbstract As a form of artificial intelligence, artificial neural networks (ANNs) have the advantages of adaptability, parallel processing capabilities,...
Αλέξανδρος Γ. Σφακιανάκης
07:39
Hepatic epithelioid hemangioendothelioma
Hepatic epithelioid hemangioendothelioma: Update on diagnosis and therapy.: Hepatic epithelioid hemangioendothelioma: Update on diagnosis and therapy.World J Clin Cases. 2020 Sep 26;8(18):3978-3987Authors: Kou K, Chen YG, Zhou JP, Sun XD, Sun DW, Li SX, Lv GYAbstract With an estimated incidence of only 1-2 cases in every 1 million people, hepatic epithelioid hemangioendothelioma (HEHE) is a rare vascular endothelial cell tumor occurring in the liver and consisting of epithelioid and histiocyte-like...
Αλέξανδρος Γ. Σφακιανάκης
07:37
Streptococcus agalactiae: Group B Streptococcus (GBS) is a normal component of the gastrointestinal and genital microbiota in humans and can lead to important infections in newborns.
Streptococcus agalactiae: Identification methods, antimicrobial susceptibility, and resistance genes in pregnant women.: Streptococcus agalactiae: Identification methods, antimicrobial susceptibility, and resistance genes in pregnant women.World J Clin Cases. 2020 Sep 26;8(18):3988-3998Authors: Santana FAF, de Oliveira TVL, Filho MBS, da Silva LSC, de Brito BB, de Melo FF, Souza CL, Marques LM, Oliveira MVAbstract BACKGROUND: Group B Streptococcus (GBS) is a normal component of the gastrointestinal...
Αλέξανδρος Γ. Σφακιανάκης
07:36
Atraumatic restorative treatment approach for class III restorations
Twelve-month evaluation of the atraumatic restorative treatment approach for class III restorations: An interventional study.: Twelve-month evaluation of the atraumatic restorative treatment approach for class III restorations: An interventional study.World J Clin Cases. 2020 Sep 26;8(18):3999-4009Authors: Shivanna MM, Ganesh S, Khanagar SB, Naik S, Divakar DD, Al-Kheraif AA, Jhugroo CAbstract BACKGROUND: Atraumatic restorative treatment (ART) may be appropriate for populations without...
Αλέξανδρος Γ. Σφακιανάκης
07:35
Effects of different doses of metformin on bone mineral density and bone metabolism in elderly male patients with type 2 diabetes mellitus.
Effects of different doses of metformin on bone mineral density and bone metabolism in elderly male patients with type 2 diabetes mellitus.: Effects of different doses of metformin on bone mineral density and bone metabolism in elderly male patients with type 2 diabetes mellitus.World J Clin Cases. 2020 Sep 26;8(18):4010-4016Authors: Wang LX, Wang GY, Su N, Ma J, Li YKAbstract BACKGROUND: Diabetes is a chronic disease, which may cause various complications. Patients with diabetes are at...
Αλέξανδρος Γ. Σφακιανάκης
07:34
Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism.
Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism.: Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism.World J Clin Cases. 2020 Sep 26;8(18):4017-4021Authors: Lei QR, Yang X, Miao CM, Wang JC, Yang YAbstract BACKGROUND: Variations in the methylene tetrahydrofolate reductase (MTHFR) gene have been reported as risk factors for numerous conditions, including cardiovascular...
Αλέξανδρος Γ. Σφακιανάκης
07:33
First-line chemotherapy in very elderly patients with metastatic pancreatic cancer: Gemcitabine monotherapy vs combination chemotherapy.
First-line chemotherapy in very elderly patients with metastatic pancreatic cancer: Gemcitabine monotherapy vs combination chemotherapy.: First-line chemotherapy in very elderly patients with metastatic pancreatic cancer: Gemcitabine monotherapy vs combination chemotherapy.World J Clin Cases. 2020 Sep 26;8(18):4022-4033Authors: Han SY, Kim DU, Seol YM, Kim S, Lee NK, Hong SB, Seo HIAbstract BACKGROUND: Combination chemotherapy (gemcitabine plus nab-paclitaxel and FOLFIRINOX) is widely used...
Αλέξανδρος Γ. Σφακιανάκης
07:33
Needleless sling in treatment of female stress urinary incontinence.
Clinical value of needleless sling in treatment of female stress urinary incontinence.: Clinical value of needleless sling in treatment of female stress urinary incontinence.World J Clin Cases. 2020 Sep 26;8(18):4043-4050Authors: Chen YG, Zhang YG, Zhang W, Li X, Wang XAbstract BACKGROUND: Stress urinary incontinence (SUI) is a common disease in women. The emergence of the needle-free sling has led to a new clinical treatment for SUI in women. AIM: To explore the clinical value...
Αλέξανδρος Γ. Σφακιανάκης
07:32
Intratympanic dexamethasone injection for sudden sensorineural hearing loss in pregnancy.
Intratympanic dexamethasone injection for sudden sensorineural hearing loss in pregnancy.: Intratympanic dexamethasone injection for sudden sensorineural hearing loss in pregnancy.World J Clin Cases. 2020 Sep 26;8(18):4051-4058Authors: Lyu YL, Zeng FQ, Zhou Z, Yan M, Zhang W, Liu M, Ke ZYAbstract BACKGROUND: As sudden sensorineural hearing loss (SSNHL) rarely occurs in pregnant women, there is a lack of knowledge and relevant research on its management. AIM: To investigate the...
Αλέξανδρος Γ. Σφακιανάκης
07:32
Tibial platform fractures.......Comparison between computed tomography and magnetic resonance imaging
Comparison between computed tomography and magnetic resonance imaging in clinical diagnosis and treatment of tibial platform fractures.: Comparison between computed tomography and magnetic resonance imaging in clinical diagnosis and treatment of tibial platform fractures.World J Clin Cases. 2020 Sep 26;8(18):4067-4074Authors: Liu XD, Wang HB, Zhang TC, Wan Y, Zhang CZAbstract BACKGROUND: Tibial plateau fracture is one of the common fracture types. It occurs mainly in teenagers and is usually...
Αλέξανδρος Γ. Σφακιανάκης
07:31
Primary sclerosing cholangitis and autoimmune hepatitis
Primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome associated with inflammatory bowel disease: A case report and systematic review.: Primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome associated with inflammatory bowel disease: A case report and systematic review.World J Clin Cases. 2020 Sep 26;8(18):4075-4093Authors: Ballotin VR, Bigarella LG, Riva F, Onzi G, Balbinot RA, Balbinot SS, Soldera JAbstract BACKGROUND: A previously healthy 22-year-old...
Αλέξανδρος Γ. Σφακιανάκης
07:29
Epidermolytic acanthoma: commonly misdiagnosed as condyloma accuminatum, verruca, and seborrheic keratosis
Epidermolytic acanthoma: A case report.: Epidermolytic acanthoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4094-4099Authors: Ginsberg AS, Rajagopalan A, Terlizzi JPAbstract BACKGROUND: Epidermolytic acanthoma (EA) is a rare benign skin lesion, usually found in the genital area of men and women, with epidermolytic hyperkeratosis as its distinguishing histologic characteristic. It is commonly misdiagnosed as condyloma accuminatum, verruca, and seborrheic keratosis. Since this lesion...
Αλέξανδρος Γ. Σφακιανάκης
07:28
Management of pembrolizumab-induced steroid refractory mucositis with infliximab...........................Η ινφλιξιμάμπη (infliximab) είναι ένα χιμαιρικό μονοκλωνικό αντίσωμα ανθρώπου-ποντικού που συνδέεται με μεγάλη χημική συγγένεια και με τους διαλυτούς και με τους διαμεμβρανικούς τύπους του TNFα (παράγοντα νέκρωσης των όγκων άλφα), αλλά όχι με τη λεμφοτοξίνη α (TNFβ). Ανατομική/θεραπευτική/χημική (ATC) ταξινόμηση Κωδικός Τίτλος Κατηγοριοποίηση L04AB02 Infliximab L Αντινεοπλασματικοί και ανοσοτροποποιητικοί παράγοντες → L04 Ανοσοκατασταλτικοί παράγοντες → L04A Ανοσοκατασταλτικοί παράγοντες → L04AB Αναστολείς του παράγοντα νέκρωσης όγκων α (TNF-α) Πηγή: Γαληνός Οδηγός Φαρμάκων
Management of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report.: Management of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report.World J Clin Cases. 2020 Sep 26;8(18):4100-4108Authors: Dang H, Sun J, Wang G, Renner G, Layfield L, Hilli JAbstract BACKGROUND: Pembrolizumab is an anti-programmed death receptor 1 (PD-1) that was shown to have a tolerable safety profile with 17% of grade 3-4 drug-related adverse events, notable...
Αλέξανδρος Γ. Σφακιανάκης
07:26
Small bowel obstruction caused by a bezoar
Small bowel obstruction caused by a bezoar following an adult simultaneous liver-kidney transplantation: A case report.: Small bowel obstruction caused by a bezoar following an adult simultaneous liver-kidney transplantation: A case report.World J Clin Cases. 2020 Sep 26;8(18):4109-4113Authors: Pan G, Kim RD, Campsen J, Rofaiel GAbstract BACKGROUND: Small bowel obstructions (SBOs) are common following a large intra-abdominal operation; however, SBOs caused by bezoars are unreported in patients...
Αλέξανδρος Γ. Σφακιανάκης
07:24
Laparoscopic resection of primary retroperitoneal schwannoma
Laparoscopic resection of primary retroperitoneal schwannoma: A case report.: Laparoscopic resection of primary retroperitoneal schwannoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4114-4121Authors: Ribeiro MA, Elias YG, Augusto SS, Néder PR, Costa CT, Maurício AD, Sampaio AP, Fonseca AZAbstract BACKGROUND: Schwannomas are rare, often benign, tumors deriving from Schwann cells that have low incidence in the retroperitoneal region (0.5% to 5%). Their diagnosis is hardly confirmed...
Αλέξανδρος Γ. Σφακιανάκης
07:24
Acute febrile neutrophilic dermatosis - Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma
Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma: A case report.: Sweet syndrome as a paraneoplastic manifestation of cholangiocarcinoma: A case report.World J Clin Cases. 2020 Sep 26;8(18):4122-4127Authors: Lemaire CC, Portilho ALC, Pinheiro LV, Vivas RA, Britto M, Montenegro M, Rodrigues LFF, Arruda S, Lyra AC, Cavalcante LNAbstract BACKGROUND: Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare skin disorder that may be associated with...
Αλέξανδρος Γ. Σφακιανάκης
07:22
Milk-aspiration
Multidisciplinary approach to suspected sudden unexpected infant death caused by milk-aspiration: A case report.: Multidisciplinary approach to suspected sudden unexpected infant death caused by milk-aspiration: A case report.World J Clin Cases. 2020 Sep 26;8(18):4128-4134Authors: Maiese A, La Russa R, Arcangeli M, Volonnino G, De Matteis A, Frati P, Fineschi VAbstract BACKGROUND: The term sudden unexpected infant death (SUID) is not always properly invoked. It refers to a broad range of...
Αλέξανδρος Γ. Σφακιανάκης
07:20
Stress fractures in the calcaneus, intermediate cuneiform bone, sacrum, tibia (bilateral), navicular bone and femoral neck
Stress fractures in uncommon location: Six case reports and review of the literature.: Stress fractures in uncommon location: Six case reports and review of the literature.World J Clin Cases. 2020 Sep 26;8(18):4135-4150Authors: Ficek K, Cyganik P, Rajca J, Racut A, Kiełtyka A, Grzywocz J, Hajduk GAbstract BACKGROUND: Individuals' interest in sports activities has been increasing, contributing to more stress fracture occurrences in uncommon locations on the skeleton. In this study, several...
Αλέξανδρος Γ. Σφακιανάκης
07:20
Celiac disease and Sjögren's syndrome
Celiac disease and Sjögren's syndrome: A case report and review of literature.: Celiac disease and Sjögren's syndrome: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4151-4161Authors: Balaban DV, Mihai A, Dima A, Popp A, Jinga M, Jurcut CAbstract BACKGROUND: Celiac disease (CD) is a systemic, chronic immune-mediated disease triggered by gluten ingestion in genetically-susceptible individuals, with a prevalence of 1% worldwide. Sjogren's syndrome (SS) is also...
Αλέξανδρος Γ. Σφακιανάκης
07:19
Adverse reaction to mesalazine: Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient
Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient - a putative adverse reaction to mesalazine: A case report and review of literature.: Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient - a putative adverse reaction to mesalazine: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4162-4168Authors: Cernomaz AT, Bordeianu G, Terinte C, Gavrilescu CMAbstract BACKGROUND: Lung and airway involvement in inflammatory bowel disease...
Αλέξανδρος Γ. Σφακιανάκης
07:18
Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.
Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.: Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report.World J Clin Cases. 2020 Sep 26;8(18):4169-4176Authors: Prídavková D, Samoš M, Kyčina R, Adamicová K, Kalman M, Belicová M, Mokáň MAbstract BACKGROUND: Insulinomas are the most common type of functioning endocrine neoplasms of the pancreas presenting hypoglycemic symptoms. Patients characteristically...
Αλέξανδρος Γ. Σφακιανάκης
07:17
Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.
Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.: Neoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports.World J Clin Cases. 2020 Sep 26;8(18):4177-4185Authors: Nomura E, Kayano H, Machida T, Izumi H, Yamamoto S, Sugawara A, Mukai M, Hasebe TAbstract BACKGROUND: Neoadjuvant chemoradiotherapy (NACRT) has not been accepted as a general therapy for gastric cancer...
Αλέξανδρος Γ. Σφακιανάκης
07:17
Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.
Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.: Unilateral pleuroparenchymal fibroelastosis as a rare form of idiopathic interstitial pneumonia: A case report.World J Clin Cases. 2020 Sep 26;8(18):4186-4192Authors: Lee JH, Jang HJ, Park JH, Kim HK, Lee S, Kim JY, Kim SHAbstract BACKGROUND: Pleuroparenchymal fibroelastosis (PPFE) is a rare idiopathic interstitial pneumonia characterized by predominantly upper lobe involvement...
Αλέξανδρος Γ. Σφακιανάκης
07:16
Superior mesenteric vein thrombosis induced by influenza infection
Superior mesenteric vein thrombosis induced by influenza infection: A case report.: Superior mesenteric vein thrombosis induced by influenza infection: A case report.World J Clin Cases. 2020 Sep 26;8(18):4193-4199Authors: Oh GM, Jung K, Kim JH, Kim SE, Moon W, Park MI, Park SJAbstract BACKGROUND: Among the various types and causes of mesenteric ischemia, superior mesenteric vein (SMV) thrombosis is a rare and ambiguous disease. If a patient presents with SMV thrombosis, past medical history...
Αλέξανδρος Γ. Σφακιανάκης
07:14
Mucinous adenocarcinoma of the buttock associated with hidradenitis
Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report.: Mucinous adenocarcinoma of the buttock associated with hidradenitis: A case report.World J Clin Cases. 2020 Sep 26;8(18):4200-4206Authors: Kim SJ, Kim TG, Gu MJ, Kim SAbstract BACKGROUND: Mucinous adenocarcinomas of the buttock are rare and have an uncertain etiology and natural course. They are usually related to chronic anal fistulas, hidradenitis suppurativa, or Crohn's disease. Here, we report a case...
Αλέξανδρος Γ. Σφακιανάκης
07:14
Perivascular epithelioid cell tumor (PEComa) : TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery
TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery: A case report and review of literature.: TFE3-expressing malignant perivascular epithelioid cell tumor of the mesentery: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4207-4214Authors: Kim NI, Lee JS, Choi YD, Ju UC, Nam JHAbstract BACKGROUND: Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor that exhibits an epithelioid and spindle cell morphology. The tumor...
Αλέξανδρος Γ. Σφακιανάκης
07:12
Robotic surgery in giant multilocular cystadenoma of the prostate
Robotic surgery in giant multilocular cystadenoma of the prostate: A rare case report.: Robotic surgery in giant multilocular cystadenoma of the prostate: A rare case report.World J Clin Cases. 2020 Sep 26;8(18):4215-4222Authors: Fan LW, Chang YH, Shao IH, Wu KF, Pang STAbstract BACKGROUND: Giant multilocular cystadenoma (GMC) of the prostate gland is a very rare benign tumor. Although the benign nature has been known, complete surgical excision is the major treatment consensus because...
Αλέξανδρος Γ. Σφακιανάκης
07:11
Multiple recurrent neurofibromas in the abdominal wall:
Multiple recurrent neurofibromas in the abdominal wall: A case report.: Multiple recurrent neurofibromas in the abdominal wall: A case report.World J Clin Cases. 2020 Sep 26;8(18):4223-4227Authors: Zhao XF, Shen YM, Chen JAbstract BACKGROUND: Neurofibroma can be a clinical manifestation of neurofibromatosis, which is a benign neurogenic tumor that occurs sporadically. Neurofibromas in the abdomen usually appear in the retroperitoneal space. Reports on neurofibromas in the abdominal wall...
Αλέξανδρος Γ. Σφακιανάκης
07:11
Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.
Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.: Mine disaster survivor's pelvic floor hernia treated with laparoscopic surgery and a perineal approach: A case report.World J Clin Cases. 2020 Sep 26;8(18):4228-4233Authors: Chen K, Lan YZ, Li J, Xiang YY, Zeng DZAbstract BACKGROUND: A pelvic floor hernia is defined as a pelvic floor defect through which the intraabdominal viscera may protrude. It is an infrequent complication...
Αλέξανδρος Γ. Σφακιανάκης
07:10
Encrusted cystitis (EC) is a chronic inflammation of the bladder associated with mucosal encrustations. Bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into the bladder submucosal tissue can be used for treatment of EC.
Successful treatment of encrusted cystitis: A case report and review of literature.: Successful treatment of encrusted cystitis: A case report and review of literature.World J Clin Cases. 2020 Sep 26;8(18):4234-4244Authors: Fu JG, Xie KJAbstract BACKGROUND: Encrusted cystitis (EC) is a chronic inflammation of the bladder associated with mucosal encrustations. Early diagnosis and optimal treatment are not well established. Here, we report a case of EC successfully treated with com-bination...
Αλέξανδρος Γ. Σφακιανάκης
07:09
Massive pulmonary haemorrhage due to severe trauma
Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report.: Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report.World J Clin Cases. 2020 Sep 26;8(18):4245-4251Authors: Zhang BY, Chen XC, You Y, Chen M, Yu WKAbstract BACKGROUND: Massive pulmonary haemorrhage can spoil the entire lung and block...
Αλέξανδρος Γ. Σφακιανάκης
07:08
Gitelman syndrome ... hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria
Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report.: Gitelman syndrome caused by a rare homozygous mutation in the SLC12A3 gene: A case report.World J Clin Cases. 2020 Sep 26;8(18):4252-4258Authors: Yu RZ, Chen MSAbstract BACKGROUND: Gitelman syndrome (GS) is an unusual, autosomal recessive salt-losing tubulopathy characterized by hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria. It is caused by mutations in the solute carrier family...
Αλέξανδρος Γ. Σφακιανάκης
07:08
Arterial embolism caused by a peripherally inserted central catheter in a very premature infant:
Arterial embolism caused by a peripherally inserted central catheter in a very premature infant: A case report and literature review.: Arterial embolism caused by a peripherally inserted central catheter in a very premature infant: A case report and literature review.World J Clin Cases. 2020 Sep 26;8(18):4259-4265Authors: Huang YF, Hu YL, Wan XL, Cheng H, Wu YH, Yang XY, Shi JAbstract BACKGROUND: Extremely premature infants have poor vascular conditions. Operators often choose deep veins...
Αλέξανδρος Γ. Σφακιανάκης
07:07
Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature
Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.: Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.World J Clin Cases. 2020 Sep 26;8(18):4272-4279Authors: Gu KC, Wan Y, Xiang L, Wang LS, Yao WJAbstract BACKGROUND: Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of meningioma and is classified as grade I (benign) tumor. It is characterized by abundant infiltrates of lymphocytes and plasma cells. Here,...
Αλέξανδρος Γ. Σφακιανάκης
07:06
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Head and NeckFacial Nerve Meningioma: A Case Mimicking Facial Nerve Schwannoma.Facial Nerve Meningioma: A Case Mimicking Facial Nerve Schwannoma. Ear Nose Throat J. 2020 Oct 06;:145561320962582 Authors: Gao W, Zi D, Lu L Abstract Facial nerve meningioma is exceedingly rare and tends to affect the geniculate ganglion. We present a case of facial nerve meningioma located in the internal auditory canal with a "labyrinthine tail," mimicking facial nerve schwannoma. The clinical and radiological features,...
Αλέξανδρος Γ. Σφακιανάκης
07:05
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Head and NeckManagement of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report.Management of pembrolizumab-induced steroid refractory mucositis with infliximab: A case report. World J Clin Cases. 2020 Sep 26;8(18):4100-4108 Authors: Dang H, Sun J, Wang G, Renner G, Layfield L, Hilli J Abstract BACKGROUND: Pembrolizumab is an anti-programmed death receptor 1 (PD-1) that was shown to have a tolerable safety profile with 17% of grade 3-4 drug-related adverse events, notable...
Αλέξανδρος Γ. Σφακιανάκης
07:04
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Annals of Intensive Care - Latest ArticlesBest-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsisSepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Despite treatment being in line with current guidelines, mortality remains high in those with septic shock. I...Annals of Intensive Care - Latest ArticlesWed Oct 07, 2020 03:00Mark above section as read Latest Results for Sports MedicineOutdoor Walking Speeds of Apparently Healthy...
Αλέξανδρος Γ. Σφακιανάκης
07:03
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  pubmed: sleep apneaPectus excavatum is associated with sleep-related breathing disorders in children.Related Articles Pectus excavatum is associated with sleep-related breathing disorders in children. Eur Respir J. 2019 10;54(4): Authors: Wada H, Kimura M, Shirahama R, Ikeda A, Gozal D, Tanigawa T PMID: 31273042 [PubMed - indexed for MEDLINE]pubmed: sleep apneaThu Oct 08, 2020 14:19Sudden Improvement in PAP Download Indices Without Treatment Change.Related Articles Sudden Improvement in PAP Download...
Αλέξανδρος Γ. Σφακιανάκης
07:02
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  American Goiter AssociationResponse Letter to the Editor from Dorin et al.: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery".Response Letter to the Editor from Dorin et al.: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery". J Clin Endocrinol Metab. 2020 Oct 08;: Authors: Prete A, Taylor AE, Bancos I, Smith DJ, Foster MA, Kohler S, Fazal-Sanderson V, Komninos J, O'Neil...
Αλέξανδρος Γ. Σφακιανάκης
07:01
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Clinical & Experimental AllergySuitability of Low‐Dose, Open Food Challenge Data to Supplement Double‐Blind, Placebo‐Controlled Data in Generation of Food Allergen Threshold Dose‐DistributionsAbstract Food allergen threshold dose‐distributions are used in food allergen risk assessment to determine the level of risk within a food allergic population to a defined exposure amount of allergenic food protein and to help inform allergen risk management decisions. There has been a long‐standing interest...
Αλέξανδρος Γ. Σφακιανάκης
07:00
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Latest Results for Sleep and BreathingThe role of antioxidant vitamins and selenium in patients with obstructive sleep apneaAbstract Purpose Obstructive sleep apnea (OSA) is a disorder characterized by recurrent episodes of obstruction of the upper respiratory tract during sleep often accompanied by oxygen desaturations. Antioxidant defense mechanisms are important to prevent OSA-associated diseases and decrease mortality. We aimed to determine the levels of selenium and vitamins A, C, and E in...
Αλέξανδρος Γ. Σφακιανάκης
06:58
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Clinical CasesCase 31-2020: A 48-Year-Old Man with Lymphoma and Abdominal PainPresentation of Case. Dr. Olivia C. Smibert: A 48-year-old man with diffuse large B-cell lymphoma was evaluated in the oncology clinic of this hospital because of abdominal pain. The patient had been generally well until 12 years before this presentation, when lymphadenopathy in the axillary and…Clinical CasesThu Oct 08, 2020 03:00Mark above section as read Operative Techniques in OtolaryngologyNeck Level Algorithm Approach...
Αλέξανδρος Γ. Σφακιανάκης
06:57
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  International Journal of Molecular SciencesIJMS, Vol. 21, Pages 7414: Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics DataIJMS, Vol. 21, Pages 7414: Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics Data International Journal of Molecular Sciences doi: 10.3390/ijms21197414 Authors: Christiana C. Christodoulou Margarita Zachariou Marios Tomazou Evangelos Karatzas Christiana A. Demetriou...
Αλέξανδρος Γ. Σφακιανάκης
06:56
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  AntibioticsAntibiotics, Vol. 9, Pages 683: Diagnostic Value of Serum Procalcitonin in Patients with Convulsion in Emergency Department, an Observational StudyAntibiotics, Vol. 9, Pages 683: Diagnostic Value of Serum Procalcitonin in Patients with Convulsion in Emergency Department, an Observational Study Antibiotics doi: 10.3390/antibiotics9100683 Authors: Hisashi Murakami Hiromu Naraba Takashi Gondo Masaki Mochizuki Hidehiko Nakano Yuji Takahashi Tomohiro Sonoo Hideki Hashimoto Kensuke Nakamura...
Αλέξανδρος Γ. Σφακιανάκης
06:55
world j clin cases
 Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report. World J Clin Cases. 2020 Sep 26;8(18):4272-4279 Authors: Gu KC, Wan Y, Xiang L, Wang LS, Yao WJ Abstract BACKGROUND: Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of meningioma and is classified as grade I (benign) tumor. It is characterized by abundant infiltrates of lymphocytes and plasma cells. Here, we report...
Αλέξανδρος Γ. Σφακιανάκης
06:53

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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