Thank you for allowing us to respond to the letter by Arshad and colleagues1 on a topical and important issue. We agree that this is an important subject that should not be overlooked.
https://ift.tt/2R7cVzo
Πέμπτη 22 Νοεμβρίου 2018
Reply to: BAPRAS and BAAPS Scientific Meetings: Are we sticking are noses up at Rhinoplasty
Response to letter commenting on the use of blue dye in sentinel lymph node biopsy
We read with interest the reply from Rudman and colleagues1 to our publication2 but disagree with their assertion that blue dye must be used to increase the accuracy of sentinel lymph node biopsy (SLNB) for melanoma. In our series, the use of blue dye did not improve the sensitivity of intra-operative sentinel node identification but increased the number of nodes harvested by 5%. Our findings correspond with a meta-analysis performed by Niebling et al in 2016,3 where pooled analysis of 66 studies showed a 99% SLN identification rate using radiocolloid without blue dye.
https://ift.tt/2PLbIkO
Double Barrel Lymphaticovenular Anastomosis
With improvements in the super-micro surgical technique, lymphaticovenular anastomosis (LVA) has become an effective treatment for obstructive lymph edema1. Recently, indocyanine green (ICG) dye lymphography makes it possible to visualize lymph vessels. LVA requires specific veins in the field. However veins come in a variety of sizes, and options for anastomosis i.e. end to end, end to side and side to end are chosen to deal with the discrepancies between lymph vessels and veins2. On the other hand, lymph vessels are sometimes bunched.
https://ift.tt/2R7jG4u
Response to ‘Sentinel lymph node biopsy in melanoma: which hot nodes should be harvested and is blue dye really necessary?’
We read with great interest Ranson et als' recent publication, 'Sentinel lymph node biopsy in melanoma: which hot nodes should be harvested and is blue dye really necessary?'.1 This article retrospectively analysed 42 nodal basins in which greater than one node had been harvested, comparing the overall sensitivity of their blue dye and radiocolloid procedures with the sensitivity that might have be achieved had, theoretically, cold blue nodes been left in situ. They state that this approach could have resulted in a 5% reduction in the number of nodes harvested with no apparent change in sensitivity.
https://ift.tt/2PLbFWa
Healing and maturation of the free Gracilis flap in extremity reconstruction: A patient perspective
Advancements in lower extremity reconstruction have made free tissue transfer for open lower limb fractures the gold standard of care in many units.1–2 Decisions regarding the use of fasciocutaneous versus muscle flaps are both surgeon and patient dependent. Muscle flaps are specifically unsightly to patients in the early stages of their reconstruction. However, the free Gracilis flap is quick to raise, with predictable anatomy, minimal donor site morbidity and is the workhorse flap for lower extremity reconstruction in our unit.
https://ift.tt/2R3uC2U
FIRST DORSAL METACARPAL FLAP REFINEMENT FOR COVERAGE OF THUMB DEFECTS
Thumb defects after crush injury or amputation are common. The first dorsal metacarpal flap or Foucher flap is an island flap that was described as an alternative in the coverage of the distal stump or any other tissue loss in the thumb.1 The donor site is the skin from the dorsal aspect of the proximal phalanx of the index finger and second metacarpal head, which is usually grafted.
https://ift.tt/2PLbzhg
Pre-operative masseter muscle EMG activation during smile predicts synchronicity of smile development in facial palsy patients undergoing reanimation with the masseter nerve – a prospective cohort study
Synchronicity of the oral commissure movement of a bilateral smile is a significant goal for reconstruction in facial reanimation and may only be guaranteed with use of the facial nerve as a donor nerve. Yet over the years several studies report some degree of spontaneity in certain patients when using a non-facial donor nerve, which indicates that synchronous initiation of the smile might be achievable with other donor nerves. We designed a prospective cohort study to evaluate whether pre-operative involuntary activation of the masseteric nerve during smile predicts development of a synchronous smile development when using the masseteric nerve for reanimation.
https://ift.tt/2R6OuCp
ALT flap with vascularized fascia lata for one-stage functional patellar tendon reconstruction
Composite Antero-Lateral Thigh (ALT) flap with vascularized fascia lata can reconstitute patellar tendon integrity and knee soft tissue coverage in one stage. However, long term evidence of outcomes is lacking. This work analyses long term functional results, comparing subtotal and total reconstruction of patellar tendon, and respective function of the extensor apparatus.
https://ift.tt/2PLbCcW
Aerosol-related thermal injuries: a simple approach to managing a frosty problem.
Invented over 80 years ago, aerosol cans are now part of our everyday life. Body deodorants and air fresheners are readily available in any supermarket. Aerosol-related frostbites are being seen more often over last two decades and many cases are seen following deliberate self-harm from readily-available deodorant cans. 'Frosting is a practice increasingly seen in paediatric and adolescent patients.1 Although occasional aerosol-related frostbites have been reported widely, no treatment guidelines have been proposed to date.
https://ift.tt/2R8cdSO
Cracking the Combination: Gut Hormones for the Treatment of Obesity and Diabetes
Abstract
Obesity and type 2 diabetes are a veritable global pandemic. There is an imperative to develop new therapies for these conditions that can be delivered at scale to patients, which deliver effective and titratable weight loss, amelioration of diabetes, prevention of diabetic complications and improvements in cardiovascular health. Although agents based on glucagon‐like peptide‐1 (GLP‐1) are now in routine use for diabetes and obesity, the limited efficacy of such drugs means that newer agents are required. By combining the effects of GLP‐1 with other gut and metabolic hormones such as glucagon (GCG), oxyntomodulin, glucose‐dependent insulinotropic peptide (GIP) and peptide YY, we may obtain improved weight loss, increased energy expenditure and improved metabolic profiles. Drugs based on dual agonism of GLP1R/GCGR and GLP1R/GIPR are being actively developed in clinical trials. Triple agonism, for example with GLPR1/GCGR/GIPR unimolecular agonists or using GLP‐1/oxyntomodulin/peptide YY, is also being explored. Multi‐agonist drugs seem set to deliver the next generation of therapies for diabetes and obesity soon.
This article is protected by copyright. All rights reserved.
https://ift.tt/2DSSqnl
Gray matter differences associated with age and sex hormone levels between premenopausal and perimenopausal women, a voxel‐based morphometry study
Abstract
Purpose
To explore brain morphological alterations associated with age and sex hormone levels between premenopausal and perimenopausal women using magnetic resonance imaging (MRI) T1‐weighted structural images.
Materials and Methods
Thirty‐two premenopausal women with a mean age of 47.75 years (S.D. = 1.55 years) and twenty‐five recently perimenopausal women with a mean age of 51.60 years (S.D. = 1.63 years) were evaluated for sex hormone levels, including prolactin (PRL), follicle‐stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), free testosterone (free‐T), and progesterone (P). A 3.0 Tesla MRI scanner was utilized to acquire T1 images. Voxel‐based morphometry (VBM) was used to evaluate changes in gray matter volume between the two groups. The general linear model was applied with false discovery rate (FDR) correction for between group voxel‐wise statistics. Spearman partial correlation analyses were conducted between age, sex hormone levels and regions of gray matter volume showing significant differences between the two groups.
Results
Compared with premenopausal women, perimenopausal women showed decreased gray matter volume in the left putamen, right pallidum, right inferior parietal gyrus (IPG), right superior frontal gyrus (SFG) (orbital part) and right postcentral gyrus (PG) (p < 0.05, FDR corrected). The gray matter volume in the left putamen and right pallidum were negatively correlated with age among the 57 enrolled women. The levels of FSH and LH were positively correlated with gray matter volume changes in the right pallidum.
Conclusion
The VBM analysis revealed that age and menopause per se lead to gray matter volume reduction in certain brain structures. These structural changes might be potential causes of sexual dysfunction, nervous system degeneration and depression, which need to be examined in future studies. Our findings might provide evidence and guide future research in understanding the menopausal transition.
This article is protected by copyright. All rights reserved.
https://ift.tt/2S6k4jG
Ghrelin receptor deletion reduces binge‐like alcohol drinking in rats
Abstract
Ghrelin is a gastric hormone that has been implicated in the neurobiology of alcohol drinking. We have recently developed a ghrelin receptor (GHSR) knockout (KO) rat model, which exhibits reduced food consumption and body weight. In addition, recent preliminary work suggests that the gut‐microbiome, which appears to interact with the ghrelin system, may modulate alcohol drinking. Here, we investigated the effects of GHSR deletion on alcohol consumption utilizing GHSR KO and wild type (WT) rats in three separate alcohol consumption paradigms: 1. operant self‐administration (30 min sessions); 2. drinking in the dark (DID; 4 h sessions); 3. intermittent access (24 h sessions). These paradigms model varying degrees of alcohol consumption. Furthermore, we sought to investigate the gut‐microbiome composition of GHSR KO and WT rats before and after alcohol exposure. We found that the GHSR KO rats self‐administered significantly less alcohol compared with WT rats in the operant paradigm, and consumed less alcohol than WT in the initial stages of the DID paradigm. No genotype differences were found in the intermittent access test. In addition, we found a significant decrease in gut‐microbial diversity after alcohol exposure in both genotypes. Thus, the present results indicate that the ghrelin system may be involved in drinking patterns that result in presumably increased alcohol exposure levels and that GHSR may constitute a potential pharmacological target for the reduction of binge‐alcohol consumption. The potential functional role of the gut‐microbiome in alcohol drinking, and interaction with the ghrelin system, is an interesting topic for further investigation.
This article is protected by copyright. All rights reserved.
https://ift.tt/2DQwUQb
Cover Image, Volume 89, Issue 6
The cover image is based on the Original Article A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease by Wei Liu et al., DOI: 10.1111/cen.13847. Design Credit: Qianyue Zhang.
https://ift.tt/2KoWlsl
Ustekinumab use in patients with severe psoriasis co‐infected with hepatitis B and/or C
Abstract
Exacerbation or reactivation of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) in persons infected with psoriasis during treatment with biologics is a documented concern with use of tumor necrosis factor (TNF) inhibitors. Much less is known, however, about these risks in relation to newer biologic drugs including ustekinumab (interleukin (IL)‐12/23 inhibition).
This article is protected by copyright. All rights reserved.
https://ift.tt/2zp7UeM
Crosstalk between Estrogen Signaling and Breast Cancer Metabolism
Publication date: Available online 22 November 2018
Source: Trends in Endocrinology & Metabolism
Author(s): Eylem Kulkoyluoglu-Cotul, Alexandra Arca, Zeynep Madak-Erdogan
Estrogens and estrogen receptors (ERs) regulate metabolism in both normal physiology and in disease. The metabolic characteristics of intrinsic breast cancer subtypes change based on their ER expression. Crosstalk between estrogen signaling elements and several key metabolic regulators alters metabolism in breast cancer cells, and enables tumors to rewire their metabolism to adapt to poor perfusion, transient nutrient deprivation, and increased acidity. This leads to the selection of drug-resistant and metastatic clones. In this review we discuss studies revealing the role of estrogen signaling elements in drug resistance development and metabolic adaptation during breast cancer progression.
https://ift.tt/2POHPAe
Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center
Background: Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). Facial papules have been associated with worse prognosis. Objectives: We sought to detect the prevalence of facial and extrafacial lesions and to analyze their relation to demographic and clinical variables in a large and ethnically diverse series of patients with FFA. Methods: Charts of patients diagnosed with FFA between January 1, 2015, and December 31, 2017, at the Department of Dermatology, University of Miami, were reviewed retrospectively. Results: 91 patients (87 women and 4 men) met inclusion criteria: 45% (n = 41) were of Hispanic/Latino ethnicity, and 34% (n = 30) were premenopausal. Facial papules were most commonly detected (41% among Hispanic/Latino patients). Significant associations were found between: (1) Hispanic/Latino ethnicity and any FFA-associated facial lesions, facial papules alone, or lichen planus pigmentosus alone, as well as premenopausal status; (2) any FFA-associated facial lesions or facial papules alone and premenopausal status; and (3) Hispanic/Latino ethnicity and simultaneous presence of facial and extrafacial lesions. Conclusions: There is a significant association among Hispanic/Latino ethnicity, facial papules, and premenopausal status, which may portend a susceptibility to severer disease and prompt early and aggressive treatment in this group.
Dermatology
https://ift.tt/2DEdxsp
Dermatology
https://ift.tt/2DEdxsp
Functionally distinct contributions of parietal cortex to a numerical landmark task: an fMRI study
Publication date: Available online 22 November 2018
Source: Cortex
Author(s): Muhammet Ikbal Sahan, Steve Majerus, Michael Andres, Wim Fias
Abstract
This study aimed at establishing the neural basis of magnitude processing of multiple numbers from working memory. We designed a numerical landmark task and embedded it in a fragmented trial event-related fMRI design, allowing to separate encoding from decision processing. An attentional localiser task not involving numbers allowed further functional specification. The results show that in a numerical landmark task the right anterior intraparietal sulcus is involved in number encoding while more posterior parietal regions, bilateral superior parietal lobule and right inferior parietal lobule, provide domain-general support in the form of constructing a working memory representation or orienting spatial attention within that mental representation during number comparison. The results are in line with earlier studies reporting a functional distinction between anterior and posterior parietal contributions to number processing and further specify their role at a functional level.
https://ift.tt/2KqsTlR
Influence of excess ligand on Nephrogenic Systemic Fibrosis associated with nonionic, linear gadolinium-based contrast agents
Publication date: Available online 22 November 2018
Source: Magnetic Resonance Imaging
Author(s): Richard C. Semelka, John P. Prybylski, Miguel Ramalho
Abstract
Background
The molecular structure, charge, thermodynamic and kinetic stability are approximately the same for gadodiamide and gadoversetamide, the main substantive difference is that gadodiamide is manufactured with 5% free ligand to form Omniscan® and gadoversetamide with 10% free ligand to form OptiMARK®.
Purpose
To determine the relative risk of Nephrogenic Systemic Fibrosis (NSF) between gadodiamide (Omniscan®) and gadoversetamide (OptiMARK®) and to explore the potential contribution of the amount of excess ligand added to their commercial formulations.
Materials and methods
In this retrospective observational study, the number of doses and NSF cases associated with these agents were calculated based on two different approaches: the number of doses was determined based on pharmaceutical companies' information, and the number of unconfounded NSF cases was obtained from the previously published literature based on a legal database. A second analysis estimates the number of doses and NSF cases from the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS).
Results
Approximately 87 million and 12 million doses of Omniscan® and OptiMARK®, respectively, have been administered worldwide since their original approval for use in the various countries throughout the world. A total of 197 and 8 unconfounded cases of NSF have been reported with Omniscan® and OptiMARK®, rendering an incidence of 2.3/million and 0.7/million for these agents, respectively. The FAERS analysis suggested reported incidences of 13.1/million and 5.0/million.
Conclusion
There is an approximately 3-fold greater incidence of NSF from Omniscan® than OptiMARK®. The difference in incidence might reflect the lesser quantity of added free ligand to the formulation of Omniscan®.
https://ift.tt/2FzlxNW
Characterization and correlation of signal drift in diffusion weighted MRI
Publication date: Available online 22 November 2018
Source: Magnetic Resonance Imaging
Author(s): Colin Hansen, Vishwesh Nath, Allison E. Hainline, Kurt G. Schilling, Prasanna Parvathaneni, Roza G. Bayrak, Justin A. Blaber, Okan Irfanoglu, Carlo Pierpaoli, Adam W. Anderson, Baxter P. Rogers, Bennett A. Landman
Abstract
Diffusion weighted MRI (DWMRI) and the myriad of analysis approaches (from tensors to spherical harmonics and brain tractography to body multi-compartment models) depend on accurate quantification of the apparent diffusion coefficient (ADC). Signal drift during imaging (e.g., due to b0 drift associated with heating) can cause systematic non-linearities that manifest as ADC changes if not corrected. Herein, we present a case study on two phantoms on one scanner. Different scan protocols exhibit different degrees of drift during similar scans and may be sensitive to the order of scans within an exam. Vos et al. recently reviewed the effects of signal drift in DWMRI acquisitions and proposed a temporal model for correction. We propose a novel spatial-temporal model to correct for higher order aspects of the signal drift and derive a statistically robust variant. We evaluate the Vos model and propose a method using two phantoms that mimic the ADC of the relevant brain tissue (0.36–2.2 × 10–3 mm2/s) on a single 3 T scanner. The phantoms are (1) a spherical isotropic sphere consisting of a single concentration of polyvinylpyrrolidone (PVP) and (2) an ice-water phantom with 13 vials of varying PVP concentrations. To characterize the impact of interspersed minimally weighted volumes ("b0's"), image volumes with b-value equal to 0.1 s/mm2 are interspersed every 8, 16, 32, 48, and 96 diffusion weighted volumes in different trials. Signal drift is found to have spatially varying effects that are not accounted for with temporal-only models. The novel model captures drift more accurately (i.e., reduces the overall change per-voxel over the course of a scan) and results in more consistent ADC metrics.
https://ift.tt/2r89sFL
Assessment of dental caries and gingival status among a group of type 1 diabetes mellitus and healthy children of South India – a comparative study
Journal Name: Journal of Pediatric Endocrinology and Metabolism
Issue: Ahead of print
https://ift.tt/2R3n40b
Cosmetics, Vol. 5, Pages 69: Enzyme-Catalysed Conversion of Atranol and Derivatives into Dimeric Hydrosoluble Materials: Application to the Preparation of a Low-Atranol Oakmoss Absolute
Cosmetics, Vol. 5, Pages 69: Enzyme-Catalysed Conversion of Atranol and Derivatives into Dimeric Hydrosoluble Materials: Application to the Preparation of a Low-Atranol Oakmoss Absolute
Cosmetics doi: 10.3390/cosmetics5040069
Authors: Hélène Bouges André Monchot Sylvain Antoniotti
Oakmoss absolute, a solvent extract from Evernia prunastri, is a valuable fragrance ingredient widely used in fine fragrance for almost two centuries. Some minor components of oakmoss absolute, such as atranol and chloroatranol, are attested contact allergens and their presence in fragrance and cosmetic products should be as low as possible. In this context, we have developed an enzyme-based protocol upon which these undesirable molecules are converted in a hydrosoluble dimeric material, and thus easily separated from the absolute by liquid–liquid extraction. Analytical and sensory analyses were performed to confirm the specificity of the process, the absence of alteration of the olfactory quality of the absolute, and the final titles of atranol and chloroatranol, which eventually were observed in the ppm range. This highly sustainable process is a viable alternative to conventional time-, energy-, and manpower-consuming techniques to produce very low-atranol oakmoss absolute.
https://ift.tt/2r0ghZW
Cosmetics, Vol. 5, Pages 68: Seaweeds as Source of Bioactive Substances and Skin Care Therapy—Cosmeceuticals, Algotheraphy, and Thalassotherapy
Cosmetics, Vol. 5, Pages 68: Seaweeds as Source of Bioactive Substances and Skin Care Therapy—Cosmeceuticals, Algotheraphy, and Thalassotherapy
Cosmetics doi: 10.3390/cosmetics5040068
Authors: Leonel Pereira
Riverine, estuarine, and coastal populations have always used algae in the development of home remedies that were then used to treat diverse health problems. The empirical knowledge of various generations originated these applications, and their mechanism of action is, in most cases, unknown, that is, few more scientific studies would have been described beyond simple collection and ethnographic recording. Nevertheless, recent investigations, carried out with the purpose of analyzing the components and causes that alter the functioning and the balance of our organism, are already giving their first results. Water, and especially sea water is considered as essential to life on our planet. It sings all the substances necessary and conducive to the development of the living being (minerals, catalysts, vitamins, amino acids, etc.). Oceans cover over 70% of Earth, being home to up to 90% of the organisms in the planet. Many rich resources and unique environments are provided by the ocean. Additionally, bioactive compounds that multiple marine organisms have a great potential to produce can be used as nutraceuticals, pharmaceuticals, and cosmeceuticals. Both primary and secondary metabolites are produced by algae. The first ones are directly implicated in development, normal growth, or reproduction conditions to perform physiological functions. Stress conditions, like temperature changes, salinity, environmental pollutants, or UV radiation exposure cause the performance of secondary metabolites. In algae, proteins, polysaccharides, fatty acids, and amino acids are primary metabolites and phenolic compounds, pigments, vitamins, sterols, and other bioactive agents, all produced in algae tissues, are secondary metabolites. These algal active constituents have direct relevance in cosmetics.
https://ift.tt/2FCRQvA
Scholar : New articles have been published for Journal of Natural History, Volume 52, Issue 39-40
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Scholar : intitle:laryngeal - new results
[PDF] Incidence of thyroid gland invasion in locally advanced laryngeal carcinoma
TN Doğan, EÜ Tuna, A Acar, M Çayönü, S Boynueğri… - Age (year), 2018
Objectives: This study aims to determine the frequency of thyroid gland invasion in
patients with locally advanced laryngeal carcinoma who were treated with total
laryngectomy and neck dissection as well as hemi-or total thyroidectomy. Patients …
patients with locally advanced laryngeal carcinoma who were treated with total
laryngectomy and neck dissection as well as hemi-or total thyroidectomy. Patients …
 |  |
[PDF] Dysplastic Changes in Patients with Recurrent Laryngeal Leukoplakia: Importance of Long-Term Follow-Up
T Marom, L Muallem-Kalmovich - IRB
Background: Leukoplakia of the vocal cords may represent a pre-cancerous lesion of
the larynx. The management of cases of recurrent leukoplakia with pathologically
proven dysplasia is still controversial. Objectives: To present a series of patients with …
the larynx. The management of cases of recurrent leukoplakia with pathologically
proven dysplasia is still controversial. Objectives: To present a series of patients with …
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This alert is sent by Google Scholar. Google Scholar is a service by Google.
Scholar : ΣΤΟΜΑΤΙΤΙΣ - νέα αποτελέσματ
[HTML] Detectable Vesicular Stomatitis Virus (VSV)–Specific Humoral and Cellular Immune Responses Following VSV–Ebola Virus Vaccination in Humans
JH Poetsch, C Dahlke, ME Zinser, R Kasonta… - The Journal of Infectious …, 2018
This study investigates preexisting and vaccine-induced vector immunity in 30
participants of a Phase-1 VSV-EBOV Ebola vaccine trial. No preexisting immunity
was detected, however humoral and cell-mediated immunity against internal VSV …
participants of a Phase-1 VSV-EBOV Ebola vaccine trial. No preexisting immunity
was detected, however humoral and cell-mediated immunity against internal VSV …
 |  |
Methods for Treating Disorders or Diseases Associated with Hyperlipidemia and Hypercholesterolemia While Minimizing Side Effects
DJ Rader - US Patent App. 16/030,703, 2018
… liver; hepatic fat build up, polyneuropathy, peripheral neuropathy,
rhabdomyolysis, arthralgia, myalgia, chest pain, rhinitis, dizziness, arthritis,
peripheral edema, gastroenteritis, liver function tests abnormal, colitis, rectal …
rhabdomyolysis, arthralgia, myalgia, chest pain, rhinitis, dizziness, arthritis,
peripheral edema, gastroenteritis, liver function tests abnormal, colitis, rectal …
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[PDF] Antibiotics and its use in pediatric dentistry: A review
TG Jayakaran, C Vishnu Rekha, S Annamalai… - 2018
… It is a potent inhibitor of obligate anaerobic bacteria and protozoa, but not
of any organism that is aerobic or incapable of anaerobic metabolism. [11]
Therapeutic Uses: [12] • Acute necrotizing ulcerative gingivitis (Vincent's …
of any organism that is aerobic or incapable of anaerobic metabolism. [11]
Therapeutic Uses: [12] • Acute necrotizing ulcerative gingivitis (Vincent's …
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[PDF] CLINICAL MANIFESTATIONS IN XLinked CARRIERS OF CHRONIC GRANULOMATOUS DISEASE
ABD Goldblatt - CHRONIC GRANULOMATOUS
… No XL-CGD carriers were found, but the authors recommended screening for carrier status
particularly in the presence of aphthous stomatitis [17]. Alongside photosensitivity and
DLE manifestations, aphthous stomatitis has been reported with even greater prevalence …
particularly in the presence of aphthous stomatitis [17]. Alongside photosensitivity and
DLE manifestations, aphthous stomatitis has been reported with even greater prevalence …
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Nicolò Paganini: Teufelsgeiger mit Madonnenhänden
T Meißner - Der prominente Patient, 2019
… Anschließend wurde eine Schwitzkur empfohlen, um das schädigende Agens,
das man im Körper vermutete, zu entfernen. Bei oraler Aufnahme
anorganischer Quecksilberverbindungen kommt es rasch zur Hypersalivation …
das man im Körper vermutete, zu entfernen. Bei oraler Aufnahme
anorganischer Quecksilberverbindungen kommt es rasch zur Hypersalivation …
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Efficacy and safety of gemcitabine and S-1 combination therapy vs gemcitabine alone for advanced pancreatic cancer: a meta-analysis of randomised controlled trials
K Ma, Q Zhao, X Wu, Y Wang, X Zhang
… group.Severe neutropenia(RR=2.33,95%CI:1.76-3.08,P0.00001),
thrombocytopenia(RR=2.02,95%CI:1.32-3.08,P=0.001)and leukocytopenia(
RR=2.53,95%CI:1.79-3.57,P0.00001)were found in GEM/S-1 group.With …
thrombocytopenia(RR=2.02,95%CI:1.32-3.08,P=0.001)and leukocytopenia(
RR=2.53,95%CI:1.79-3.57,P0.00001)were found in GEM/S-1 group.With …
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[PDF] The Effect of Adding Coconut Oil on Candida albicans Activity and Shear Bond Strength of Acrylic Based Denture Soft Lining Material
BM Alamen, GAH Naji
… ABSTRACT One of the most serious problems of soft denture lining materials during usage
is the accumulation of microorganisms. This problem is presented as denture induced
stomatitis, which caused by the fungal growth especially Candida albicans …
is the accumulation of microorganisms. This problem is presented as denture induced
stomatitis, which caused by the fungal growth especially Candida albicans …
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[PDF] FUTURE DIRECTIONS IN CGD RESEARCH
RA Seger, BH Segal, TW Kuijpers, D Roos - CHRONIC GRANULOMATOUS
… 71, 73, 78, 79, 80, 81, 82, 85, 87, 168 Anemia, 178 Antibacterial Prophylaxis,
108 anti-CD52, 319 antifungal cellular immunity, 399 Antifungal Prophylaxis,
109 anti-inflammatory signals, 165 Antimicrobial Activity, v, 35 anti-thymocyte …
108 anti-CD52, 319 antifungal cellular immunity, 399 Antifungal Prophylaxis,
109 anti-inflammatory signals, 165 Antimicrobial Activity, v, 35 anti-thymocyte …
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[HTML] Enhancing Protective Efficacy of Poultry Vaccines through Targeted Delivery of Antigens to Antigen-Presenting Cells
A Shrestha, JR Sadeyen, M Iqbal - Vaccines, 2018
Avian viral diseases including avian influenza, Marek's disease and Newcastle
disease are detrimental to economies around the world that depend on the
poultry trade. A significant zoonotic threat is also posed by avian influenza …
disease are detrimental to economies around the world that depend on the
poultry trade. A significant zoonotic threat is also posed by avian influenza …
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Dosage Considerations for Canakinumab in Children with Periodic Fever Syndromes
L Zhuang, J Chen, J Yu, A Marathe, C Sahajwalla… - Clinical Pharmacology & …
… (FMF), hyperimmunoglobulin D syndrome/mevalonate kinase deficiency
(HIDS/MKD), tumor necrosis factor (TNF) receptor associated periodic
syndrome (TRAPS), and periodic fever, aphthous-stomatitis, pharyngitis …
(HIDS/MKD), tumor necrosis factor (TNF) receptor associated periodic
syndrome (TRAPS), and periodic fever, aphthous-stomatitis, pharyngitis …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.
Scholar : Decannulation - νέα αποτελέσματα
[PDF] Robert L. Wilkins James K. Stoller Craig L. Scanlan
M Mosby
Page 1. Robert L. Wilkins James K. Stoller Craig L. Scanlan M Mosby Page 2. Common
Medical Abbreviations Used in Charting ABG arterial blood gas ICU intensive care unit
ac before meals IM intramuscular ad lib. as desired iv, rv intravenous …
Medical Abbreviations Used in Charting ABG arterial blood gas ICU intensive care unit
ac before meals IM intramuscular ad lib. as desired iv, rv intravenous …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.
Scholar : ΒΑΣΗ ΚΡΑΝΙΟΥ - νέα αποτελέσματα
[PDF] Οδηγίες για μετακινήσεις ενήλικα ημιπληγικού ασθενή
Π Ευγενοπούλου, Α Παπαθεοδώρου - 2018
… Η άνω και οι δύο πλάγιες επιφάνειες εφάπτονται με τον θόλο του κρανίου
(Παρασκευάς, 2008) … επεξεργασία του λόγου. Η βάση των δυνάμεων του λόγου
βρίσκεται στο αριστερό ημισφαίριο … 5 και δύο κλάδους, στον έσω και στον …
(Παρασκευάς, 2008) … επεξεργασία του λόγου. Η βάση των δυνάμεων του λόγου
βρίσκεται στο αριστερό ημισφαίριο … 5 και δύο κλάδους, στον έσω και στον …
| |
Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.
Scholar : ΙΛΙΓΓΟΣ - νέα αποτελέσματα
[PDF] Οδηγίες για μετακινήσεις ενήλικα ημιπληγικού ασθενή
Π Ευγενοπούλου, Α Παπαθεοδώρου - 2018
… Β) Ασταθές βάδισμα, Γ) Ίλιγγος, ζάλη, διπλωπία, δυσαρθρία και αιμωδία στο πρόσωπο,
Δ) Αισθητικές διαταραχές ή πάρεση ετερόπλευρα ή αμφοτερόπλευρα … συζυγιών που
εκδηλώνεται ως διπλωπία (διπλή όραση), δυσφαγία, δυσαρθρία, κώφωση και ίλιγγος …
Δ) Αισθητικές διαταραχές ή πάρεση ετερόπλευρα ή αμφοτερόπλευρα … συζυγιών που
εκδηλώνεται ως διπλωπία (διπλή όραση), δυσφαγία, δυσαρθρία, κώφωση και ίλιγγος …
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Scholar : ΛΟΓΟΣ - νέα αποτελέσματα
New Frontiers in Heidegger's Original Ethics: Hermeneutics and the Λόγος of the Environmentalist Argument
F Schalow - Heidegger Studies, 2018
Throughout the past three decades, Heidegger's original ethics (ursprüngliche Ethik)
has inspired various attempts to forge a completely new landscape for addressing
perennial concerns within environmental philosophy, deep ecology, and animal …
has inspired various attempts to forge a completely new landscape for addressing
perennial concerns within environmental philosophy, deep ecology, and animal …
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[HTML] CJS Hayward: The Complete Works
CJS Hayward
… The Orthodox believe, as Catholics still do on paper if not in practice, that
we have a logos (from the Greek λογοσ, meaning the part of the mind we
use to keep track of facts related to corporate logos), and a noose (from the …
we have a logos (from the Greek λογοσ, meaning the part of the mind we
use to keep track of facts related to corporate logos), and a noose (from the …
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[PDF] "¿ DE DÓNDE SACAS ESA AGUA?" LAS RELIGIONES COMO RESERVAS DE SENTIDO. APORTES PARA UNA PRAXIS NO VIOLENTA
H Lascano - Octavio Marino Pedoni (Ed.)
… Si "en el principio" no fue la división sino el λόγος–es decir, la razón que
es tanto comprensión cuanto comunicación–, entonces, después de siglos
de recíprocas desavenen- cias, estamos actualmente en el καιρός, el tiempo …
es tanto comprensión cuanto comunicación–, entonces, después de siglos
de recíprocas desavenen- cias, estamos actualmente en el καιρός, el tiempo …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.
Scholar : Obstructive sleep apnea - νέα αποτελέσματα
A validation study on three screening questionnaires for obstructive sleep apnea in a Korean community sample
HJ Jeon, YR Bang, IY Yoon - Sleep and Breathing, 2018
Purpose Obstructive sleep apnea (OSA) is highly prevalent and causes serious
cardiovascular complications. Several screening questionnaires for OSA have been
introduced, but only few validation studies have been conducted in general …
cardiovascular complications. Several screening questionnaires for OSA have been
introduced, but only few validation studies have been conducted in general …
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Laparoscopic Roux-En-Y Gastric Bypass Versus Sleeve Gastrectomy on Pelvic Floor Disorders in Morbidly Obese Women: a Prospective Monocentric Pilot Study
C Mazoyer, P Treacy, L Turchi, PA Lehur, E Benizri… - Obesity Surgery, 2018
… All patients fulfilled the criteria for BS according the NIH consensus conference [24]: BMI
of ≥ 40 or of 35 with at least one comorbid condi- tion, including type 2 diabetes (T2D),
blood hypertension (HT), obstructive sleep apnea syndrome (OSAS), or joint ar- thritis …
of ≥ 40 or of 35 with at least one comorbid condi- tion, including type 2 diabetes (T2D),
blood hypertension (HT), obstructive sleep apnea syndrome (OSAS), or joint ar- thritis …
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SELF-EXPANDING NERVE CUFF ELECTRODE
BK Ng, W Dai - US Patent App. 15/967,468, 2018
… The present invention generally relates to implantable neurostimulation
leads, and specifically relates to implantable nerve cuff electrodes that can
be used to stimulate nerves to treat ailments, such as obstructive sleep …
leads, and specifically relates to implantable nerve cuff electrodes that can
be used to stimulate nerves to treat ailments, such as obstructive sleep …
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Preoperative Evaluation
MD Yamini Subramani, M Nagappa, T Mubashir - Preoperative Patient Evaluation, an …, 2018
… Do you often feel tired, fatigued, or sleepy during the daytime (such as falling
asleep during … H, Peters J. Corticosteroids and inhaled salbutamol in pa-
tients with reversible airway obstruction markedly decrease the … Part …
asleep during … H, Peters J. Corticosteroids and inhaled salbutamol in pa-
tients with reversible airway obstruction markedly decrease the … Part …
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The Gut Feelings of Medical Culture
M Mathias, AM Moore - Gut Feeling and Digestive Health in Nineteenth …, 2018
… 4. Tripathi et al., "Intermittent Hypoxia and Hypercapnia, a Hallmark of
Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome";
Armstrong and Armstrong, "Interactions of Gut Microbiota, Endotoxemia …
Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome";
Armstrong and Armstrong, "Interactions of Gut Microbiota, Endotoxemia …
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Methods and apparatus for skin color patient monitoring
S Kokolis - US Patent App. 15/641,045, 2018
… In particular, sawtooth red shift patters have been associated with obstructive artery
disease during the work supporting this invention. Sawtooth red shift patterns during
a stress test are indicative that further diagnostic steps …
disease during the work supporting this invention. Sawtooth red shift patterns during
a stress test are indicative that further diagnostic steps …
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[PDF] Wearable health devices—vital sign monitoring, systems and technologies
JP Cunha, DF Dias - 2018
… Respiratory rate ambulatory monitoring is important in the detection of symptoms of
respiratory diseases such as sleep apnea syndrome, chronic obstructive pulmonary
disease and asthma, improving Page 7. Sensors 2018, 18, 2414 7 of 28 …
respiratory diseases such as sleep apnea syndrome, chronic obstructive pulmonary
disease and asthma, improving Page 7. Sensors 2018, 18, 2414 7 of 28 …
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[PDF] ВОЗМОЖНОСТИ СОВЕРШЕНСТВОВАНИЯ ПОНЯТИЯ И БАЗИСНЫХ ЮРИДИЧЕСКИХ СВОЙСТВ ДОКАЗАТЕЛЬСТВ И ИХ ДОПУСТИМОСТИ В …
ЮО Ланцедова - 2018
… Г..... 45 Page 4. International Multidisciplinary Conference 4 MEDICINE IN A
CONTEMPORARY CONTEXT Prevalence and risk factors of obstructive sleep
apnea syndrome in Ukrainian population Andreieva Ya …
CONTEMPORARY CONTEXT Prevalence and risk factors of obstructive sleep
apnea syndrome in Ukrainian population Andreieva Ya …
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GLYCOLIC ACID PROTECTS AGAINST ISCHEMIC INSULTS
F Pan-montojo - US Patent App. 15/776,817, 2018
… or with concomitant diseases such as high blood pressure, obesity, sleep
apnea, periodontal diseases … disease, artery or blood vessel conditions
and/or ischemic obstructive or occlusive … arterial segments, producing an …
apnea, periodontal diseases … disease, artery or blood vessel conditions
and/or ischemic obstructive or occlusive … arterial segments, producing an …
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[HTML] Nasal Congestion-Deviated Septum & Turbinate Hypertrophy
NCD Septum, AQ Truong, ENT Bellevue
… loss of smell, chronic mouth breathing, and snoring when you are exerting
physically (such as exercising) or when you are sleeping … "Improvement
in quality of life after nasal surgery alone for patients with obstructive sleep …
physically (such as exercising) or when you are sleeping … "Improvement
in quality of life after nasal surgery alone for patients with obstructive sleep …
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Summary Insulinomas are rare neuroendocrine tumours that classically present with fasting hypoglycaemia. This case report discusses an un...
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