Nasopharyngeal Approach to a Cholesterol Granuloma of the Petrous Apex

xlomafota13 shared this article with you from Inoreader Nasopharyngeal Approach to a Cholesterol Granuloma of the Petrous Apex Via ear nose throat Ear Nose Throat J. 2021 Jul 8:1455613211028074. doi: 10.1177/01455613211028074. Online ahead of print. ABSTRACT Cholesterol granulomas are rare cystic inflammatory lesions characterized by the formation of cholesterol crystals. They are the most prevalent lesions of the petrous apex and when symptomatic, hearing loss, vertigo, tinnitus, headache, and facial pathology can be present. Surgical management is recommended in symptomatic patients. There are different surgical appr oaches to cholesterol granulomas. The aim of this article is to present and describe an endoscopic endonasal nasopharyngeal approach to a cholesterol granuloma and explain the advantages and disadvantages. PMID:34233514 | DOI:10.1177/01455613211028074 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Solitary vaginal paraganglioma with mature sacrococcygeal teratoma: a rare case report

xlomafota13 shared this article with you from Inoreader Solitary vaginal paraganglioma with mature sacrococcygeal teratoma: a rare case report Via radioactive iodine BMC Endocr Disord. 2021 Jul 7;21(1):145. doi: 10.1186/s12902-021-00806-6. ABSTRACT BACKGROUND: Vaginal paraganglioma are rare, atypical, solitary tumors which originate from the female genital tract. Sacrococcygeal teratoma are also rare neoplasms which derive from one (or more) primordial germ cell layers. Here we report a unique case of vaginal paraganglioma with sacrococcygeal teratoma. CASE PRESENTATION: A 44-year-old female experienced paroxysmal hypertension, palpitatio ns and dizziness for almost six years. Enhanced CT and MRI highlighted two abnormal soft tissue lesions located in the left vaginal wall and coccyx anteriorly, and Iodine-131 metaiodobenzylguanidine (131I-MIBG) demonstrated abnormal radioactive uptake in perineum area. Endocrine tests showed elevated plasma normetanephrine (NMN) and 24 h urine norepinephrine. There was a well-circumscribed soft tissue lesion of approximately 3.5 cm in the left lateral vaginal wall which could be palpated during bimanual examination, together with a 1.5 cm tumor in the posterior wall of the rectum. We completely resected the two lesions in stages with the support of a senior gynecologist and general surgeons. Postoperative histopathological examinations suggested the vaginal paraganglioma and mature sacrococcygeal teratoma. Targeted sanger sequencing for the 36 mostly common paraganglioma-related genes, with a depth of 1000x, revealed no mutations. Post-operatively, plasma NMN and 24 h uri ne norepinephrine returned to the normal range and her symptoms completely disappeared. CONCLUSIONS: We reported an extremely rare case and the successful treatment of functional vaginal paraganglioma coexisting with adult sacrococcygeal teratoma. PMID:34233670 | DOI:10.1186/s12902-021-00806-6 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Regarding Use of Povidone Iodine to Reduce Nasopharyngeal Viral Load in Patients With COVID-19

xlomafota13 shared this article with you from Inoreader Regarding Use of Povidone Iodine to Reduce Nasopharyngeal Viral Load in Patients With COVID-19 Via JAMA Otolaryngology–Head & Neck Surgery Current Issue To the Editor We read with interest the recent article by Guenezan et al, "Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial," published in JAMA Otolaryngology–Head and Neck Surgery on the use of nasal and oral application of 1% povidone iodine (PVP-I) solution in nonadmitted patients with COVID-19. We congratulate the authors for publishing this highly relevant clinical data pertaining to the ongoing pandemic. Despite the rollout of safe vaccination, the final outcome of SARS-CoV-2 remains to be seen. Until the definitive data emerges (possibly even beyond then), the importance of preventive strategies cannot be overemphasized. The wide availability and antimicrobial spectrum (including virucidal properties against SARS-CoV-2 demonstrated i n the in vitro studies) make it an attractive agent for limiting the infection spread. The current pilot study provides important preliminary data and may boost larger-scale studies to reach more definitive conclusions. However, for the readers' benefit and possible optimization of future study designs, we would like to gain more clarity regarding some of the facts presented in the study. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telangiectasia

xlomafota13 shared this article with you from Inoreader Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telangiectasia Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This case report describes a middle-aged man with severe recurrent epistaxis refractory to medical therapy who underwent operative ablation of intranasal telangiectasias. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Use of Near-Infrared Molecular Imaging For Localizing Visually Occult Parathyroid Glands in Ectopic Locations

xlomafota13 shared this article with you from Inoreader Use of Near-Infrared Molecular Imaging For Localizing Visually Occult Parathyroid Glands in Ectopic Locations Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This proof-of-principle clinical trial examines use of intraoperative molecular imaging for localizing visually occult parathyroid glands in both anatomic and ectopic locations. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Fluorescence Imaging to Identify Occult and Ectopic Parathyroid Glands—Revealing the Unseen

xlomafota13 shared this article with you from Inoreader Fluorescence Imaging to Identify Occult and Ectopic Parathyroid Glands—Revealing the Unseen Via JAMA Otolaryngology–Head & Neck Surgery Current Issue In this issue of JAMA Otolaryngology—Head & Neck Surgery, Kennedy and colleagues describe intraoperative molecular imaging (IMI) using the near-infrared (NIR) agent indocyanine green (ICG) to identify parathyroid glands. One of the most important contributions of this study is that it directly compares 2 methods of fluorescent imaging—use of autofluorescence ("label-free") vs use of ICG as a contrast agent. The use of IMI demonstrated superior signal-to-background ratios (SBRs) compared with autofluorescence. Excitingly, in the 2 patients who underwent reexploration parathyroidectomy, IMI successfully localized the ectopic parathyroid gland, which could not be identified by conventional methods. These results suggest that IMI is an accurate and reproducible method for localizing parathyroid glands and that ICG imaging is supe rior to autofluorescence for parathyroid gland identification. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Regarding Use of Povidone Iodine to Reduce Nasopharyngeal Viral Load in Patients With COVID-19—Reply

xlomafota13 shared this article with you from Inoreader Regarding Use of Povidone Iodine to Reduce Nasopharyngeal Viral Load in Patients With COVID-19—Reply Via JAMA Otolaryngology–Head & Neck Surgery Current Issue Reply We thank Singh and colleagues for their great interest in our study. We agree that the strength of our study was to have performed viral cultures to determine whether the virus was still infectious, and therefore potentially transmissible. A decrease in viral titer at day 1 after inclusion was observed in patients receiving povidone iodine nasopharyngeal decolonization (7%; 95% CI, 43%-95% vs 32%; 95% CI, 10%-65%), but the difference was not significant, as reflected by the overlap in 95% CIs. This finding could be attributed to a lack of power of the study. An imbalance in patient characteristics between groups despite randomization, favored by the small sample size, cannot be excluded either. Patients in the intervention group were younger and had fewer comorbidities, although again the difference was not significant. This may ac count in part for the greater decline in viral titer at day 1 in the intervention group. Unfortunately, no adjustment of the results for age was feasible owing to the small sample size. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Efficacy and Safety of Propranolol vs Atenolol in Infants With Problematic Infantile Hemangiomas

xlomafota13 shared this article with you from Inoreader Efficacy and Safety of Propranolol vs Atenolol in Infants With Problematic Infantile Hemangiomas Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This randomized clinical trial compares the efficacy and safety of propranolol vs atenolol in Chinese infants with problematic infantile hemangiomas. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Association Between COVID-19 Vaccination and Sudden Hearing Loss

xlomafota13 shared this article with you from Inoreader Preliminary Analysis of Association Between COVID-19 Vaccination and Sudden Hearing Loss Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cross-sectional study examines the national incidence of sudden sensorineural hearing loss after COVID-19 vaccination using data from the CDC Vaccine Adverse Events Reporting System. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Total Thyroidectomy vs Lobectomy for Management of Papillary Thyroid Microcarcinoma

xlomafota13 shared this article with you from Inoreader Total Thyroidectomy vs Lobectomy for Management of Papillary Thyroid Microcarcinoma Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This survey study assessed surgeons' preference for total thyroidectomy vs lobectomy to treat patients with papillary thyroid cancer. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Nasal Septal Abscess Resulting From Poorly Fitting Dentures

xlomafota13 shared this article with you from Inoreader Nasal Septal Abscess Resulting From Poorly Fitting Dentures Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This case report describes a woman in her 50s who presented with nasal septal abscess resulting from poorly fitting dentures that resulted in translocation of oral flora into the nasal septum. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Associations of Baseline Frailty Status and Age With Outcomes After Vestibular Schwannoma Resection

xlomafota13 shared this article with you from Inoreader Associations of Baseline Frailty Status and Age With Outcomes After Vestibular Schwannoma Resection Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cross-sectional study evaluates the independent associations of chronological age and frailty (physiological age) with outcomes following vestibular schwannoma resection. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

COVID-19 caused hearing loss

xlomafota13 shared this article with you from Inoreader COVID-19 caused hearing loss Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Jul 8. doi: 10.1007/s00405-021-06951-x. Online ahead of print. ABSTRACT PURPOSE: The objective of this cross-sectional study was to determine if there is a potential link between COVID-19 infection and hearing loss. METHODS: The prospective study was conducted in the COVID Hospital Clinical Centre Niš, Serbia. We performed tonal audiometry and used a custom questionnaire and medical histories to determine the incidence of hearing loss in COVID-19 positive patients. RESULTS: There were 74 patients with COVID-19 that met the inclusion criteria of this study and they composed our experimental group. Fifty-four (73%) were men and 20 (27%) women. There were 30 (40.5%) patients with hearing loss. Seventeen patients had unilateral and 13 had bilateral hearing loss. Significant differences between hearing loss groups and control group were found across all age groups, but not at all frequencies. No important differences were found when unilateral hearing loss and bilateral hearing loss groups were compared. There were no significant differences in distributions of comorbidities between the patients with hearing loss and normal hearing patients. CONCLUSIONS: We found that 30 (40.5%) of the COVID-19 positive patients had sensorineural type of hearing loss. Across all age groups, there were statistically significant differences in frequencies between the COVID-19 positive patients and the control group. There were no significant differences in distributions of comorbidities between the patients with hearing loss and normal hearing patients. Distribution of unilateral and bilateral hearing loss and audiogram types was also not significantly different between the age groups. PMID:34235578 | DOI:10.1007/s00405-021-06951-x View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.