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Τρίτη 20 Σεπτεμβρίου 2016

Novel Insights into PML-Dependent Oncosuppression

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Publication date: Available online 20 September 2016
Source:Trends in Cell Biology
Author(s): Lorenzo Galluzzi
At odds with its nuclear counterpart, extranuclear promyelocytic leukemia constitutively inhibits autophagy, hence limiting cancer progression. These data raise the interesting possibility that some tumor suppressors have become specialized to operate at multiple subcellular compartments for counteracting different aspects of the oncogenic process.



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