Lipid Measurements Fasting or Nonfasting, Women or Men

I read the article by Driver et al. (1), which was recently published in the Journal, with great interest. The investigators reported that to assess the initial risk of atherosclerotic cardiovascular disease in an untreated patient, fasting or nonfasting total cholesterol and high-density lipoprotein cholesterol (HDL-C) levels provide all that is required. Among those with a nonfasting non–HDL-C level ≥220 mg/dl, a familial cause of hyperlipidemia should be suspected and evaluated further (1).

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