Recent advances in cardiac regeneration: Stem cell, biomaterial and growth factors

Publication date: March 2017
Source:Biomedicine & Pharmacotherapy, Volume 87
Author(s): Mostafa Cheraghi, Mehrdad Namdari, Babak Negahdari, Ali Eatemadi
Myocardial infarction has been reported to be responsible for about 7.3 million deaths each year globally. Present treatments for myocardial infarction have been more palliative rather than curative. Over the past few years, stem cells have demonstrated its potency in regenerating damaged cardiac tissue, especially after myocardial infarction. However, limited short half-life of the protein and cell therapy and low transplanted cell survival rate as demonstrated via several clinical trials have lead to development of more potent and novel delivery systems like biomaterial delivery system and the use of various growth factors. In this review, we will be enumerating and discussing the recent advances in cardiac regeneration with focus on stem cell, biomaterial and growth factors.



http://ift.tt/2hy2iqk