Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

Publication date: April 2017
Source:Data in Brief, Volume 11
Author(s): Alexander V. Tyakht, Veronika B. Dubinkina, Vera Y. Odintsova, Konstantin S. Yarygin, Boris A. Kovarsky, Alexander V. Pavlenko, Dmitry S. Ischenko, Anna S. Popenko, Dmitry G. Alexeev, Anastasiya Y. Taraskina, Regina F. Nasyrova, Evgeny M. Krupitski, Nino V. Shalikiani, Igor G. Bakulin, Petr L. Shcherbakov, Lyubov O. Skorodumova, Andrei K. Larin, Elena S. Kostryukova, Rustam A. Abdulkhakov, Sayar R. Abdulkhakov, Sergey Y. Malanin, Ruzilya K. Ismagilova, Tatiana V. Grigoryeva, Elena N. Ilina, Vadim M. Govorun
Alcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We collected 99 stool samples from the patients with alcoholic dependence syndrome (n=72) and alcoholic liver cirrhosis (n=27). Each of the samples was surveyed using "shotgun" (whole-genome) sequencing on SOLiD platform. The reads are deposited in the ENA (project ID: PRJEB18041).



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