Quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging predicts histological grade of hepatocellular carcinoma

Publication date: Available online 11 January 2017
Source:Clinical Imaging
Author(s): Hong-fei Tong, Hong-bo Liang, Zhi-kang Mo, Tian-pei Guan, Jian Yang, Chi-hua Fang
ObjectiveTo confirm the histological grade of hepatocellular carcinoma (HCC) by gadoxetic acid-enhanced MRI.MethodsNinety-five HCC patients underwent gadoxetic acid-enhanced MRI before surgical intervention. The correlations among the signal absolute enhancement, contrast enhancement ratio (CER) and tumor histological grade were analyzed.ResultsThe correlation between CER of tumor-to-liver and the grades of tumor differentiation is the most significant negative. The k-value for the CER of tumor-to-liver and histopathologic analysis is 0.62, which gives evidence of good agreement.ConclusionThe quantitative analysis of gadoxetic acid-enhanced MRI can predict the histological grades of small HCCs.



http://ift.tt/2jb4KVf