RSV Takes Control of Neonatal Breg Cells: Two Hands on the Wheel

Publication date: 21 February 2017
Source:Immunity, Volume 46, Issue 2
Author(s): Peter J.M. Openshaw
The viral attachment protein of RSV has many surprising features, especially its mimicry of fractalkine (CX3CL1). Zhivaki et al. (2017) now show that, in addition to using this homology to attach to ciliated cells, it activates human neonatal regulatory B cells, thereby inhibiting immunological responses.

Teaser

The viral attachment protein of RSV has many surprising features, especially its mimicry of fractalkine (CX3CL1). Zhivaki et al. (2017) now show that, in addition to using this homology to attach to ciliated cells, it activates human neonatal regulatory B cells, thereby inhibiting immunological responses.


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