Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration

Publication date: April 2017
Source:Data in Brief, Volume 11
Author(s): Sabina Wischin, Cristina Castañeda-Patlán, Martha Robles-Flores, Jesús Chimal-Monroy
Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.



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