Management of Locally Advanced Gastroesophageal Cancer

Publication date: Available online 29 March 2017
Source:Hematology/Oncology Clinics of North America
Author(s): Salah-Eddin Al-Batran, Sylvie Lorenzen

Teaser

The outcome of patients with locally advanced, resectable gastric cancer, or adenocarcinoma of the gastroesophageal junction is poor. In clinical trials, multimodality therapy, such as perioperative chemotherapy, preoperative or postoperative chemoradiation, or adjuvant chemotherapy led to significant increments in survival. Therefore, experts agree that patients with stage II or III disease should be offered a multidisciplinary treatment approach. However, patients are treated somewhat differently in the different regions of the world and survival rates remain far from being satisfactory. Efforts to further improve outcome are highly warranted.


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