Differences in the imaging features and distribution of non-indolent and indolent mastocytosis: a single institution experience of 29 patients

Publication date: Available online 6 May 2017
Source:Clinical Imaging
Author(s): Yan Epelboym, Abhishek R. Keraliya, Sree Harsha Tirumani, Jason L. Hornick, Nikhil H. Ramaiya, Atul B. Shinagare
PurposeCompare imaging features of indolent and non-indolent mastocytosis.MethodsFor 29 patients, imaging features, imaging indications, and distribution of indolent and non-indolent mastocytosis subtypes were analyzed.Results16/29 (55%) patients had three distinct patterns of osseous abnormality, not significantly differing between cohorts. Non-indolent disease was more likely to present with hepatomegaly (p=0.0004), splenomegaly (p=0.0097), and lymphadenopathy (p=0.0079). CT, was the most common initial imaging modality, ordered to stage disease in 20 of 29 patients (69%).ConclusionUnderstanding patterns of involvement of indolent and nonindolent mastocytosis across modalities could assist radiologists in evaluating mastocytosis.



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