Penicillium citrinum: opportunistic pathogen or idle bystander? A case analysis with demonstration of galactomannan cross-reactivity

Publication date: Available online 22 May 2017
Source:Medical Mycology Case Reports
Author(s): Shayla E. Hesse, Paul M. Luethy, John H. Beigel, Adrian M. Zelazny
We present a case of an immunocompromised woman with fever, pulmonary infiltrates and multiple bronchoalveolar lavage (BAL) cultures positive for Penicillium citrinum with a concomitant high BAL galactomannan level. We report the results of Aspergillus galactomannan testing performed on culture supernatants from her P. citrinum strain that confirmed the suspected cross-reactivity. Finally, we discuss the clinical significance and antifungal susceptibility of P. citrinum in our case and review the literature.



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