An Atypical Presentation of Paget’s Disease of the Breast without Nipple Involvement: Case Report and Review of the Literature

Publication date: Available online 10 June 2017
Source:Pathology - Research and Practice
Author(s): Justine S. Broecker, Charles W. Sewell, Bahig M. Shehata, Bahar Memis, Nazmi V. Adsay, Toncred M. Styblo
We present a case of a 63 year-old Caucasian female who developed a right breast skin lesion discrete from the nipple that was subsequently diagnosed as Paget's Disease of the breast (PDB). Imaging did not reveal an underlying breast cancer or involvement of the nipple. The patient underwent a segmental mastectomy preserving the nipple and final pathology demonstrated residual Paget's disease of the skin and did not reveal any additional underlying breast carcinoma. To our knowledge, this case represents the first reported diagnosed case of isolated PDB without nipple involvement.



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