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Παρασκευή 2 Ιουνίου 2017

Perioperative use of beta-blockers in vascular and endovascular surgery

Editor—We were disappointed to read the content of the recent article by Hajibandeh and colleagues1 in the British Journal of Anaesthesia. Since the early, implausible reports of long-term benefit attributable to short-term perioperative beta-blockade, there has been increasing scepticism of this treatment among both anaesthetists and cardiologists.2–8 Following the early criticisms of publications by Mangano and colleagues and Poldermans' group, the specialty of anaesthesia has discovered that the conclusions of these workers were baseless.9 This is because of a flawed analysis on the basis of 'intention to treat' with respect to the study by Mangano and colleagues and a seriously discredited first author in the case of the Poldermans' study.283

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