Differentiation of low- and high-grade clear cell renal cell carcinoma: Tumor size versus CT perfusion parameters

Publication date: Available online 3 July 2017
Source:Clinical Imaging
Author(s): Chao Chen, Qinqin Kang, Bing Xu, Hairuo Guo, Qiang Wei, Tiegong Wang, Hui Ye, Xinhuai Wu
PurposeTo compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC).Materials and methodsTumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed.ResultsHigh-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did.ConclusionsTumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.



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