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Τρίτη 25 Ιουλίου 2017

Scholar : These new articles for Xenobiotica are available online

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New for Xenobiotica and online now on Taylor & Francis Online:

Original Articles

The metabolism and drug-drug interaction potential of the selective prostacyclin receptor agonist selexipag
Carmela Gnerre, Jérôme Segrestaa, Swen Seeland, Päivi Äänismaa, Thomas Pfeifer, Stephane Delahaye, Ruben de Kanter, Tomohiko Ichikawa, Tetsuhiro Yamada & Alexander Treiber
Pages: 1-50 | DOI: 10.1080/00498254.2017.1357088This is the author accepted version which has not been proofed or edited


Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims
Raghava Choudary Palacharla, Ramakrishna Nirogi, Venkatesham Uthukam, Arunkumar Manoharan, Ranjith Kumar Ponnamaneni & Ilayaraja Kalaikadhiban
Pages: 1-43 | DOI: 10.1080/00498254.2017.1354267This is the author accepted version which has not been proofed or edited


Research Article

In vitro evaluation of the inhibition and induction potential of olaparib, a potent poly(ADP-ribose) polymerase inhibitor, on cytochrome P450
Alex McCormick, Helen Swaisland, Venkatesh Pilla Reddy, Maria Learoyd & Graeme Scarfe
Pages: 1-10 | DOI: 10.1080/00498254.2017.1346332


Absorption, metabolism and excretion of [14C]omarigliptin, a once-weekly DPP-4 inhibitor, in humans
Shiyao Xu, Dan Tatosian, Ian Mcintosh, Maria Caceres, Catherine Matthews, Koppara Samuel, Diana Selverian, Sanjeev Kumar & Eunkyung Kauh
Pages: 1-8 | DOI: 10.1080/00498254.2017.1346333


Identification of three new phase II metabolites of a designer drug methylone formed in rats by N-demethylation followed by conjugation with dicarboxylic acids
Monika Židková, Igor Linhart, Marie Balíková, Michal Himl, Veronika Dvořáčková, Eva Lhotková & Tomáš Páleníček
Pages: 1-8 | DOI: 10.1080/00498254.2017.1349964


Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment
Yuki Hori, Yasumasa Shimizu & Tetsuya Aiba
Pages: 1-8 | DOI: 10.1080/00498254.2017.1349969


Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19
Akiko Toda, Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Takashi Kusama, Makiko Shimizu, Yasuhiro Uno, Masayuki Mogi, Erika Sasaki & Hiroshi Yamazaki
Pages: 1-7 | DOI: 10.1080/00498254.2017.1353716


Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates
Shotaro Uehara, Yasuhiro Uno, Toru Oshio, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki
Pages: 1-7 | DOI: 10.1080/00498254.2017.1354138


Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor
Jamie E. Moscovitz, Zhiwu Lin, Nathaniel Johnson, Meihua Tu, Theunis C. Goosen, Yan Weng & Amit S. Kalgutkar
Pages: 1-9 | DOI: 10.1080/00498254.2017.1353163


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