Screening performance for callosal agenesis in prenatal life. Single center study

Publication date: Available online 1 August 2017
Source:Clinical Imaging
Author(s): Hubert Huras, Magdalena Nowak, Izabela Herman-Sucharska, Malgorzata Radon-Pokracka, Agnieszka Nocun, Marcin Wiechec
Objectives1) To analyze screening performance of second trimester scan for ACC, 2) to evaluate the agreement between ultrasound and MRI and 3) to compare prenatal and postnatal diagnosis.MethodsIt was a prospective observational study. All patients with fetuses suspected of ACC were referred to prenatal MRI (pMRI).ResultsOne subject was not confirmed by pMRI with the diagnosis of ACC. This case demonstrated partial ACC in neonatal MRI (nMRI).ConclusionSensitivity of second trimester scan for callosal agenesis of 73% and specificity of 99%. Prenatal MRI and US has similar amount of misdiagnoses.



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