Developing Neutrophils Must Eat…Themselves!

Publication date: 19 September 2017
Source:Immunity, Volume 47, Issue 3
Author(s): Zhichao Fan, Klaus Ley
In this issue of Immunity, Riffelmacher et al. (2017) show that autophagy is necessary for the release of free fatty acids from intracellular stores within neutrophil precursor cells. This limits glycolysis, increases oxidative phosphorylation, and is essential for neutrophil maturation.

Teaser

In this issue of Immunity, Riffelmacher et al. (2017) show that autophagy is necessary for the release of free fatty acids from intracellular stores within neutrophil precursor cells. This limits glycolysis, increases oxidative phosphorylation, and is essential for neutrophil maturation.


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