Computed tomography coronary angiography for evaluation of children with Kawasaki disease

Publication date: Available online 23 October 2017
Source:Current Problems in Diagnostic Radiology
Author(s): Manphool Singhal, Surjit Singh, Pankaj Gupta, Avinash Sharma, Niranjan Khandelwal, Jane C Burns
ObjectiveWe sought to assess the feasibility of CTCA on a 128-slice, dual source scanner in children with acute and convalescent phase KD.Materials and MethodsA prospective study of 49 children with KD (12 at presentation and 37 in the convalescent phase) was conducted between November 2013 and April 2015. CTCA was performed with either prospective (n=37) or retrospective (n=12) electrocardiographic gating. A radiologist blinded to clinical profile and echocardiogram evaluated each scan.ResultsMedian age (36 boys, 13 girls) was seven years. Median dose-length product (DLP) value and median effective CT radiation dose was 32 mGy.cm (IQR =21–74) and 0.54mSv (IQR= 0.77–3.2) for all scans and 27 mGy.cm (IQR=18.5–33.75) and 0.48mSv (IQR=0.18–1.17) for prospectively triggered scans (n=37). Fourteen subjects (30 coronary segments) showed abnormalities by CTCA including aneurysms (n=27) and stenoses (n=3). In the acute phase (n=12), aneurysms were detected in five children (18 segments).ConclusionCTCA allows comprehensive evaluation of coronary arteries in children with KD.



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