Germline Genome Protection on an Evolutionary Treadmill

Publication date: 9 October 2017
Source:Developmental Cell, Volume 43, Issue 1
Author(s): Yuh Chwen G. Lee, Mia T. Levine
Preservation of genome integrity is a conserved, essential function, yet genome defense machinery evolves rapidly. In this issue of Developmental Cell, Parhad et al. (2017) harness an evolution-guided approach to define the genetic determinants of genome defense and to reveal the molecular and cellular mechanisms shaped by adaptive evolution.

Teaser

Preservation of genome integrity is a conserved, essential function, yet genome defense machinery evolves rapidly. In this issue of Developmental Cell, Parhad et al. (2017) harness an evolution-guided approach to define the genetic determinants of genome defense and to reveal the molecular and cellular mechanisms shaped by adaptive evolution.


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