Three-dimensional versus two-dimensional shear-wave elastography: Associations of mean elasticity values with prognostic factors and tumor subtypes of breast cancer

Publication date: March–April 2018
Source:Clinical Imaging, Volume 48
Author(s): Hyun Jung Kang, Jin You Kim, Nam Kyung Lee, Ji Won Lee, You Seon Song, Shin Young Park, Jong Ki Shin
PurposeTo explore associations between prognostic factors and subtypes of invasive breast cancer (IBC) and elasticity values using three-dimensional (3D) and two-dimensional (2D) shear-wave elastography (SWE).Materials and methodsMean elasticity values (kPa) of 121 IBCs were measured using both 3D and 2D SWE. Associations between these values and prognostic factors and subtypes were analyzed using linear regression model.ResultsIn both 3D and 2D SWE, larger size and presence of lymphovascular invasion were independent factors influencing higher mean elasticity on multivariate analyses (all p values<0.05).ConclusionsUsing either 3D or 2D SWE, higher mean elasticity values are associated with poor prognostic factors of IBC.



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