Ex-vivo flush of the limb allograft reduces inflammatory burden prior to transplantation

Passenger leukocytes and inflammatory debris transferred from the donor limb to the recipient can induce allorecognition, which activates the host immune response. This is the first study to evaluate whether the transfer of this inflammatory burden can be reduced via post-preservation flush prior to revascularisation, and whether this is influenced by ischaemia.

http://ift.tt/2jX4Em6