Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib Phosphate in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

Conditions:   Biliary System Disorder;   BRCA1 Gene Mutation;   BRCA2 Gene Mutation;   Gastroesophageal Junction Adenocarcinoma;   Homologous Recombination Deficiency;   Metastatic Pancreatic Adenocarcinoma;   PALB2 Gene Mutation;   Stage IV Colorectal Cancer AJCC v7;   Stage IV Pancreatic Cancer AJCC v6 and v7;   Stage IVA Colorectal Cancer AJCC v7;   Stage IVB Colorectal Cancer AJCC v7
Interventions:   Drug: Fluorouracil;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Liposomal Irinotecan;   Drug: Rucaparib Phosphate
Sponsors:   Academic and Community Cancer Research United;   National Cancer Institute (NCI)
Not yet recruiting

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