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Σάββατο 4 Νοεμβρίου 2017

The Diagnostic Accuracy of Video EEG Without Event Capture

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Publication date: Available online 3 November 2017
Source:Pediatric Neurology
Author(s): Andrew Knox, Ravindra Arya, Paul S. Horn, Katherine Holland
ObjectiveThe aim of this study was to quantify the accuracy of 24 hour video EEG (vEEG) for the diagnosis of epilepsy when a patient's typical paroxysmal event was not captured (no-event vEEG).MethodsWe performed a retrospective chart review of all first-time 24 hour no-event vEEG studies at Cincinnati Children's Hospital Medical Center. Clinician diagnosis of epilepsy with a minimum of one year follow-up was used as the reference standard to calculate diagnostic accuracy. Sensitivity and specificity of routine EEG (rEEG) and vEEG were compared in patients with both studies, and factors affecting the accuracy of vEEG were explored with a multivariable analysis.ResultsNo-event vEEG showed sensitivity of 0.54 (95% CI 0.44 - 0.64) and specificity of 0.88 (95% CI 0.84 – 0.92) respectively, with a diagnostic odds ratio of 7.53 (95% CI 4.45-12.76). The sensitivity of vEEG was statistically superior to that of rEEG, while specificity was comparable. Age emerged as the only factor that affected the diagnostic accuracy of no-event vEEG.ConclusionEven in the absence of a typical seizure or spell, video EEG is a useful test for predicting or excluding epilepsy, with diagnostic accuracy that is superior to rEEG and unaffected by the presence of a chronic neurologic condition.



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