Visibility of mammographically occult breast cancer on diffusion-weighted MRI versus ultrasound

Publication date: May–June 2018
Source:Clinical Imaging, Volume 49
Author(s): Nita Amornsiripanitch, Habib Rahbar, Averi E. Kitsch, Diana L. Lam, Brett Weitzel, Savannah C. Partridge
PurposeTo investigate the visibility of mammographically occult breast cancers on diffusion-weighted MRI (DWI) versus ultrasound.Materials and methodsMammographically occult breast cancers (n=60) initially detected on contrast-enhanced MRI that underwent pre-biopsy targeted ultrasound were retrospectively evaluated for visibility on DWI and ultrasound.ResultsMore cancers were visible on DWI than ultrasound (78% vs. 63%; p=0.049), with 32 (53%) visible on both and 7 (12%) not visible on either. Visibility differences were more significant in larger lesions (92% vs. 68%, p=0.006).ConclusionDWI may detect more mammographically occult cancers than ultrasound, warranting further investigation as an alternative supplemental screening technique.



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