Evaluating Perceived Naturalness of Facial Expression After Fillers to the Nasolabial Folds and Lower Face With Standardized Video and Photography

BACKGROUND Hyaluronic acid (HA) fillers are commonly used in treating facial wrinkles and folds but have not been studied with standardized methodology to include assessment of standard facial expressions. OBJECTIVE To assess perceived naturalness of facial expression after treatment with 2 HA fillers manufactured with XpresHAn Technology (also known as Optimal Balance Technology). MATERIALS AND METHODS Treatment was directed to the nasolabial folds (NLFs) and at least 1 additional lower face wrinkle or fold. Maintenance of naturalness, attractiveness, and age at 1 month after optimal treatment were assessed using video recordings and photographs capturing different facial animations. Global aesthetic improvement, subjects' satisfaction, and safety were also evaluated. RESULTS The treatment was well tolerated. Naturalness of facial expression in motion was determined to be at least maintained in 95% of subjects. Attractiveness was enhanced in 89% of subjects and 79% of subjects were considered to look younger. Most subjects assessed their aesthetic appearance as improved and were satisfied with their treatment. CONCLUSION Naturalness and attractiveness can be assessed using video recordings and photographs capturing different facial animations. XpresHAn Technology HA filler treatments create natural-looking results with high subject satisfaction. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. Address correspondence and reprint requests to: Wolfgang G. Philipp-Dormston, MD, Hautzentrum Köln, Schillingsrotter Str. 39-41, 50996 Cologne, Germany, or e-mail: mail@haut-zentrum.com Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the full text and PDF versions of this article on the journal's Web site (http://ift.tt/2bw6lgr). Galderma provided W.G. Philipp-Dormston, B. Schuster, and M. Podda with a camera, investigational products, and reimbursed costs for subject participation. W.G. Philipp-Dormston has given lectures, consulted, participated in advisory board meetings and clinical studies, and has received honorariums for those by Galderma. M. Podda has consulted, lectured, or participated in advisory board meetings for Galderma. B. Schuster reports of no further financial interest with Galderma besides involvement in the study. M.K. Larsson and C. Wong are affiliated with Galderma. The FACE-Q is owned by Memorial Sloan Kettering Cancer Center (MSKCC). Drs. Cano, Klassen, and Pusic are co-developers of the FACE-Q and, as such, receive a share of any license revenues based on MSKCC's inventor sharing policy. © 2017 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

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