Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia

Publication date: Available online 15 December 2017
Source:Microbes and Infection
Author(s): Tonney S. Nyirenda, Wilson L. Mandala, Melita A. Gordon, Piero Mastroeni
Malaria and anaemia are key underlying factors for iNTS disease in African children. Knowledge of clinical and epidemiological risk-factors for iNTS disease has not been paralleled by an in-depth knowledge of the immunobiology of the disease. Herein, we review human and animal studies on mechanisms of increased susceptibility to iNTS in children.



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