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Τετάρτη 13 Δεκεμβρίου 2017

Intrarectal fixative for positioning of the prostate for intensity modulated radiotherapy

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Janos Stumpf, Subathira Balasundaram, P. G. G. Kurup, Rathnadevi Ramadas, Murali Venkatraman, Karthikeyan Perumal

Journal of Cancer Research and Therapeutics 2017 13(6):1050-1052

Dose escalation improves local control in carcinoma prostate, but rectal toxicity remains a concern. Various techniques have been there to reduce the dose to the rectum. Mobility of the prostate results in a necessary expansion of the target volume. We describe a new intrarectal fixative, developed in-house with transrectal ultrasonography through the fixative itself for localization of the organ by reporting a case with early carcinoma prostate. Concerns of rectal toxicity limit dose escalation in the treatment of prostate cancer. Intra- and interfraction prostate motion is a concern in dose conformity techniques. The intrarectal fixative system developed in-house physically separates the prostate and rectum during radiation treatment. Thus, both intra- and inter-fractional movement of the organ are addressed, therefore planning target volume expansion can be kept minimal.

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