Route Connection: Mouth to Intestine in Colitis

Publication date: 13 December 2017
Source:Cell Host & Microbe, Volume 22, Issue 6
Author(s): Naohiro Inohara
In a recent study published in Science, Atarashi et al. (2017) showed that Klebsiella strains isolated from the saliva of Crohn's disease patients can induce Th1 cell responses to promote colitis. Their findings highlight the importance of the oral cavity as a potential reservoir for bacteria that can promote intestinal disease.

Teaser

In a recent study published in Science, Atarashi et al. showed that Klebsiella strains isolated from the saliva of Crohn's disease patients can induce Th1 cell responses to promote colitis. Their findings highlight the importance of the oral cavity as a potential reservoir for bacteria that can promote intestinal disease.


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