Protein Kinase CK2: An Emerging Regulator of Immunity

Publication date: Available online 4 January 2018
Source:Trends in Immunology
Author(s): Sara A. Gibson, Etty N. Benveniste
Although it has historically been studied in the context of cancer, recent literature has highlighted the importance of the highly conserved serine/threonine kinase casein kinase II (CK2) in inflammatory disorders. Most strikingly, CK2 is a major regulator of the Th17–Treg axis relevant to many T cell-driven autoimmune disorders including multiple sclerosis (MS).



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