Reslizumab (Cinqair) [Internet].

Asthma is a common chronic respiratory disorder characterized by reversible airway obstruction, pulmonary inflammation, airway hyper-responsiveness, and airway remodelling., Patients with asthma typically present with paroxysmal or persistent symptoms of wheezing, dyspnea, chest tightness, sputum production, and coughing that are associated with airflow limitation and airway hyper-responsiveness to endogenous and exogenous stimuli (e.g., exercise; viral respiratory infections; or exposure to certain allergens, irritants, or gases). Severe eosinophilic asthma is an asthma phenotype characterized by the presence of eosinophils in the airways and sputum, despite compliance with conventional asthma therapy. Severe asthma can have a profound effect on patients' day-to-day lives, such as limiting physical activity, reducing performance at work or school, restricting social interactions, and leading to stigma. It may also necessitate frequent physician and emergency room visits.

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