AMPK Wars: the VMH Strikes Back, Return of the PVH

Publication date: Available online 6 February 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Miguel López
Hypothalamic AMP-activated protein kinase (AMPK) is an important modulator of whole-body energy homeostasis, particularly within the ventromedial nucleus, where it regulates energy expenditure, glucose, and lipid metabolism. A recent paper in Cell Reports has demonstrated that AMPK in the paraventricular nucleus of the hypothalamus modulates dietary preference for carbohydrate over fat.



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