Economic Evaluation of Unfractionated Heparin Versus Low-Molecular-Weight Heparin to Prevent Venous Thromboembolism in General Medical and Non-Orthopedic Surgical Patients [Internet].

Deep vein thrombosis (DVT) and pulmonary embolism (PE) constitute venous thromboembolism (VTE), which is common in hospitalized patients and is a major source of morbidity and mortality in both medical and non-orthopedic surgery patients. VTE is one of the most common preventable causes of in-patient mortality; among more than seven million patients discharged from 944 North American acute care hospitals, post-operative VTE was the second most common medical complication, the second most common cause of excess length of stay, and the third most common cause of excess mortality and costs. As such, strategies to reduce the occurrence of VTEs are critical in at-risk patients, and prophylactic administration of heparin has emerged as a standard of care.

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