Ετικέτες

Πέμπτη 1 Μαρτίου 2018

Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese

Abstract

Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE1, which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered.

This article is protected by copyright. All rights reserved.



http://ift.tt/2GQW26H

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αναζήτηση αυτού του ιστολογίου