Ετικέτες

Πέμπτη 22 Μαρτίου 2018

Normalization and the Cholinergic Microcircuit: A Unified Basis for Attention

Publication date: Available online 22 March 2018
Source:Trends in Cognitive Sciences
Author(s): Taylor W. Schmitz, John Duncan
Attention alters three key properties of population neural activity – firing rate, rate variability, and shared variability between neurons. All three properties are well explained by a single canonical computation – normalization – that acts across hierarchically integrated brain systems. Combining data from rodents and nonhuman primates, we argue that cortical cholinergic modulation originating from the basal forebrain closely mimics the effects of directed attention on these three properties of population neural activity. Cholinergic modulation of the cortical microcircuit underlying normalization may represent a key biological basis for the rapid and flexible changes in population neuronal coding that are required by directed attention.



http://ift.tt/2G12OH6

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αναζήτηση αυτού του ιστολογίου