Long-Term Transcriptional Gene Silencing by RNA Viruses

Publication date: Available online 11 April 2018
Source:Trends in Biochemical Sciences
Author(s): Juozas Baltusnikas, Saulius Satkauskas, Kenneth Lundstrom
Long-term transcriptional gene silencing has been hampered by delivery issues. A potential solution is the application of RNA viruses that generate small RNAs without any DNA intermediate. Long-term therapy for various diseases is expected after a single administration.



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