miR-33: A Metabolic Conundrum

Publication date: Available online 21 April 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Anders M. Näär
The miR-33 microRNAs (miRNAs) are crucial regulators of cholesterol/lipids, and may represent therapeutic targets for the treatment of atherosclerosis. A recent report by Price et al. showed that miR-33 knockout (KO) mice exhibit obesity, insulin resistance, and increased food intake, suggesting that metabolic regulation by miR-33 is more complex than was previously known.



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