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Σάββατο 30 Ιουνίου 2018

Scholar : Xenobiotica, Volume 48, Issue 9, September 2018 is now available online on Taylor & Francis Online

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Xenobiotica, Volume 48, Issue 9, September 2018 is now available online on Taylor & Francis Online.



This new issue contains the following articles:

General Xenobiochemistry

Changes in hepatic phase I and phase II biotransformation enzyme expression and glutathione levels following atrazine exposure in female rats | Open Access
Arthur D. Zimmerman, Charles B. Breckenridge, Kun D. Yi, Pragati Sawhney Coder, Desiree Wanders, Robert L. Judd & Chad D. Foradori
Pages: 867-881 | DOI: 10.1080/00498254.2017.1374486


The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes
Gurinder Walia, Alexander D. Smith, Zoe Riches, Abby C. Collier & Michael W. H. Coughtrie
Pages: 882-890 | DOI: 10.1080/00498254.2017.1376260


Extrapolation of plasma clearance to understand species differences in toxicokinetics of bisphenol A | Open Access
Torka Poet & Sean Hays
Pages: 891-897 | DOI: 10.1080/00498254.2017.1379626


Combined effect of telmisartan and fluvastatin on arachidonic acid metabolism in human liver microsomes
Yuka Kato, Yuji Mukai, Anders Rane, Nobuo Inotsume & Takaki Toda
Pages: 898-903 | DOI: 10.1080/00498254.2017.1384079


Clinical Pharmacokinetics and Metabolism

Clinical evaluation of P-glycoprotein inhibition by venetoclax: a drug interaction study with digoxin
Manoj S. Chiney, Rajeev M. Menon, Orlando F. Bueno, Bo Tong & Ahmed Hamed Salem
Pages: 904-910 | DOI: 10.1080/00498254.2017.1381779


Animal Pharmacokinetics and Metabolism

Impaired liver cytochrome P450 2C11 activity after dual antiplatelet therapy with aspirin and clopidogrel in rats
Chenyu Qian, Xi Luo, Mengbi Yang, Jing Jin & Zhong Zuo
Pages: 911-919 | DOI: 10.1080/00498254.2017.1380242


Evaluation of the pharmacokinetics, tissue distribution and excretion studies of YMR-65, a tubulin polymerization inhibitor with potential anticancer activity, in rats using UPLC-MS/MS
Ali Fan, Yaliang Zhang, Qing Zhang, Jiali Wei, Xiaoyu Lu, Guanghui Ren, Di Zhao, Ning Li, Hailiang Zhu & Xijing Chen
Pages: 920-926 | DOI: 10.1080/00498254.2017.1380865


Metabolite profile analysis and pharmacokinetic study of emodin, baicalin and geniposide in rats
Jing Yu, Xiucai Guo, Qingqing Zhang, Ying Peng & Jiang Zheng
Pages: 927-937 | DOI: 10.1080/00498254.2017.1382748


Molecular Toxicology

The downfall of TBA-354 – a possible explanation for its neurotoxicity via mass spectrometric imaging
Sphamandla Ntshangase, Adeola Shobo, Hendrik G. Kruger, Arndt Asperger, Dagmar Niemeyer, Per I. Arvidsson, Thavendran Govender & Sooraj Baijnath
Pages: 938-944 | DOI: 10.1080/00498254.2017.1375168


Topics in Xenobiochemistry

Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion
Ranjeet Prasad Dash, Rana Rais & Nuggehally R. Srinivas
Pages: 945-957 | DOI: 10.1080/00498254.2017.1376765


The influence of physicochemical properties on the reactivity and stability of acyl glucuronides
Patrick Camilleri, Akshay Buch, Brandi Soldo & Andrew J. Hutt
Pages: 958-972 | DOI: 10.1080/00498254.2017.1384967


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