Publication date: Available online 9 June 2018
Source:Trends in Biochemical Sciences
Author(s): Yongde Luo, Weiqin Lu, Xiaokun Li
Metabolic homeostasis is critical to cellular and organismal health. The newly revealed crystal structures of the endocrine factors FGF21 and FGF23, in association with the glycosidase coreceptor Klotho and transmembrane tyrosine kinase FGFR, set a platform for structure-based novel drug design against common metabolic disorders.
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Κυριακή 10 Ιουνίου 2018
Unraveling Endocrine FGF Signaling Complex to Combat Metabolic Diseases
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Publication date: January–February 2018 Source: Materials Today, Volume 21, Issue 1 Author(s): David Bradley http://ift.tt/2BP...
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Summary 外阴佩吉特病(VPD)是一种罕见的皮肤疾病,常见于绝经后的白人女性,它会引起外阴周围的皮肤瘙痒或灼烧。这种疾病有不同的类型,并且在过去,所有类型的 VPD 都与乳腺、肠道和泌尿系统的恶性肿瘤(如癌症)有关。这项来自荷兰的研究着眼于皮肤非侵入性 VPD, 其中在诊...
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