Scholar : Xenobiotica, Volume 48, Issue 10, October 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content Xenobiotica, Volume 48, Issue 10, October 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: General Xenobiochemistry Metabolism of megestrol acetate in vitro and the role of oxidative metabolites Larry House, Michael J. Seminerio, Snezana Mirkov, Jacqueline Ramirez, Maxwell Skor, Joseph R. Sachleben, Masis Isikbay, Hari Singhal, Geoffrey L. Greene, Donald Vander Griend, Suzanne D. Conzen & Mark J. Ratain Pages: 973-983 | DOI: 10.1080/00498254.2017.1386335 Changes in CYP2D enzyme activity following induction of type 2 diabetes, and administration of cinnamon and metformin: an experimental animal study Ali Taheri, Hoda Lavasani, Sara Kasirzadeh, Behjat Sheikholeslami, Yalda H. Ardakani & Mohammad-Reza Rouini Pages: 984-989 | DOI: 10.1080/00498254.2017.1390626 Stereoselective in vitro metabolism of rhynchophylline and isorhynchophylline epimers of Uncaria rhynchophylla in rat liver microsomes Xin Wang, Zhou Qiao, Jia Liu, Mei Zheng, Wenyuan Liu & Chunyong Wu Pages: 990-998 | DOI: 10.1080/00498254.2017.1390627 The potent mechanism-based inactivation of CYP2D6 and CYP3A4 with fusidic acid in in vivo bioaccumulation Xiu-Xian Lin, Guang-Hui Lian, Ying Xu, Qing Zhao, Jian Xiao, Shi-Fang Peng, Mei-Fang Xiao, Dong-Sheng Ouyang, Zhi-Rong Tan, Yi-Cheng Wang, Jing-Bo Peng, Wei Zhang & Yao Chen Pages: 999-1005 | DOI: 10.1080/00498254.2017.1390628 Clinical Pharmacokinetics and Metabolism Mass balance and metabolism of Z-215, a novel proton pump inhibitor, in healthy volunteers Ryoko Toda, Tomoharu Miyagawa, Yuka Masuda, Yusuke Hoshino, Kazuyoshi Yoshii, Masamichi Hirayama, Minaka Shibuya & Yoshihiro Kawabata Pages: 1006-1020 | DOI: 10.1080/00498254.2017.1390625 Animal Pharmacokinetics and Metabolism Characterizing the in vitro species differences in N-glucuronidation of a potent pan-PIM inhibitor GNE-924 containing a 3,5-substituted 6-azaindazole Molly Lin, Justin Ly, Ryan Takahashi, John Chen, Alan Deese, Sarah J. Robinson, Aleksandr Kolesnikov, Susan Wong, Xiaojing Wang & Jae H. Chang Pages: 1021-1027 | DOI: 10.1080/00498254.2017.1373312 Quercetin nanoparticles alter pharmacokinetics of bromocriptine, reflecting its enhanced inhibitory action on liver and intestinal CYP 3A enzymes in rats Suresh Palle & Prasad Neerati Pages: 1028-1036 | DOI: 10.1080/00498254.2017.1390277 Xenobiotic Transporters In vitro studies with two human organic anion transporters: OAT2 and OAT7 Sumathy Mathialagan, Chester Costales, Laurie Tylaska, Emi Kimoto, Anna Vildhede, Jillian Johnson, Nathaniel Johnson, Takami Sarashina, Kenta Hashizume, Caleb D. Isringhausen, Lydia M. M. Vermeer, Andrea R. Wolff & A. David Rodrigues Pages: 1037-1049 | DOI: 10.1080/00498254.2017.1384595 MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2 Charles Awortwe, Meike Kaehler, Bernd Rosenkranz, Ingolf Cascorbi & Henrike Bruckmueller Pages: 1050-1058 | DOI: 10.1080/00498254.2017.1390624 Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1 Hiroyoshi Koide, Masayuki Tsujimoto, Ai Takeuchi, Miyu Tanaka, Yoko Ikegami, Mayu Tagami, Syoko Abe, Miki Hashimoto, Tetsuya Minegaki & Kohshi Nishiguchi Pages: 1059-1071 | DOI: 10.1080/00498254.2017.1393582 Pharmacogenetics Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models Takashi Kusama, Akiko Toda, Makiko Shimizu, Shotaro Uehara, Takashi Inoue, Yasuhiro Uno, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki Pages: 1072-1077 | DOI: 10.1080/00498254.2017.1393121 Corrigendum Correction to: Koide et al., Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1 Pages: x-x | DOI: 10.1080/00498254.2018.1434920 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.