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Σάββατο 23 Φεβρουαρίου 2019

Open‐label, Investigator‐Initiated, Single Site Exploratory Trial Evaluating Secukinumab, an anti IL17A monoclonal antibody, for Patients with Moderate‐to‐Severe Hidradenitis Suppurativa

Abstract

Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease of the apocrine gland‐rich intertriginous areas.1 HS lesions have an elevated Th17 immune response, and it is often challenging to treat patients, with existing therapies having limited efficacy.2,3 We sought to investigate the role of secukinumab, a human monoclonal antibody that inhibits Interleukin‐17A, in HS treatment.

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