Antigen-Primed CD8+ T Cells Call DCs for Back Up

Publication date: 21 February 2017
Source:Immunity, Volume 46, Issue 2
Author(s): Marianne Burbage, Sebastian Amigorena
Encounters between naive T lymphocytes and dendritic cells (DCs) bearing adequate co-stimulatory signals are rare. In this issue of Immunity, Brewitz et al. (2017) show that chemokines secreted by CD8⁺ T cells recruit myeloid and plasmacytoid DCs that in turn boost CD8⁺ T cell activation.

Teaser

Encounters between naive T lymphocytes and dendritic cells (DCs) bearing adequate co-stimulatory signals are rare. In this issue of Immunity, Brewitz et al. (2017) show that chemokines secreted by CD8⁺ T cells recruit myeloid and plasmacytoid DCs that in turn boost CD8⁺ T cell activation.


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