Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia

Publication date: June 2017
Source:Medical Mycology Case Reports, Volume 16
Author(s): Dany Tager, Anne Hatch, Jennifer Segar, Brentin Roller, Mayar Al Mohajer, Tirdad T. Zangeneh
Central Nervous System (CNS) vasculitis is the most common life-threatening complication of coccidioidal meningitis. It is manifested by cerebral ischemia, hemorrhage, and infarction. We report a case of CNS vasculitis in a patient receiving chemotherapy and review of the literature on coccidioidal meningitis. The patient was treated with combination antifungal therapy and a short course of high dose corticosteroids with a modest improvement in her neurological examination after initiation of steroids.



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