NICE DSU Technical Support Document 9: The Identification, Review and Synthesis of Health State Utility Values from the Literature [Internet].

Health state utility values (HSUVs) are important parameters in decision models, and NICE requires evidence that HSUV estimates from the published literature have been identified and selected systematically. NICE provides a reference case analysis with specific requirements for how HSUVs are derived, including a preference for HSUV values derived from the EQ-5D. This Technical Support Document (TSD) discusses how to systematically identify and select HSUVs from the literature in order to meet the requirements of the NICE Methods Guide. In addition, the TSD provides guidance on quality and relevance assessment, data extraction, selection of values and synthesis. Two case studies are used throughout this document; a review of HSUVs in osteoporosis-related conditions and a review of HSUVs in breast cancer.

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