Measuring liver cyst volumes on MRI or cyst volumes above in autosomal dominant polycystic kidney disease (ADPKD)

Publication date: Available online 12 July 2017
Source:Clinical Imaging
Author(s): Zerwa Farooq, Ashkan Heshmatzadeh Behzadi, Jon D. Blumenfeld, Yize Zhao, Martin R. Prince
PurposeTo compare segmentation methods for measuring liver cyst volumes in ADPKD.MethodsLiver cyst volumes in 42 ADPKD patients were measured using region growing, thresholding and cyst diameter techniques. Manual segmentation was the reference standard.ResultsRoot mean square deviation was 113, 155, and 500 for cyst diameter, thresholding and region growing respectively. Thresholding error for cyst volumes below 500ml was 550% vs 17% for cyst volumes above 500ml (p<0.001).ConclusionCyst diameter and manual segmentation are recommended to measure volume of small number of cysts. For severe disease with numerous, large hepatic cysts, thresholding is an acceptable alternative.



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