Development of Au nanowire injector system to deliver plasmid into mouse embryo

Publication date: October 2017
Source:Data in Brief, Volume 14
Author(s): Kkotchorong Park, Keun Cheon Kim, Hyoban Lee, Yoori Sung, Mijeong Kang, Yun Mi Lee, Ji Yeon Ahn, Jeong Mook Lim, Taejoon Kang, Bongsoo Kim, Eun Ju Lee
In this data article, we developed a Au nanowire injector (Au NWI) for directly delivering plasmid into the 1-cell stage of the mouse embryos designed to successfully attach and detach the plasmid on the Au NWI, highly minimizing physical and chemical damage on the embryos. This data presents that a Au NWI system does not induce detrimental damages on development of embryos and efficiently express the green fluorescence protein in vitro. The data provided herein is in association with the research article related to reduce the occurrence of mosaicism by a Au NWI," Suppressing Mosaicism by Au Nanowire Injector-driven Direct Delivery of Plasmids into Mouse Embryos" (Park et al., 2017 [1]).



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