Publication date: Available online 31 January 2018
Source:Trends in Cell Biology
Author(s): Christophe Viret, Aurore Rozières, Mathias Faure
NDP52/CALCOCO2 makes multiple contributions to selective autophagy. By interacting with cargos and LC3, NDP52 directs autophagy targets to autophagosomes. In addition, NDP52 promotes autophagosomes fusion with endolysosomes by connecting autophagosomes to MYOSIN VI. Recent studies reveal that Rab35 GTPase controls NDP52 recruitment to its targets and that NDP52 triggers MYOSIN VI (MYO6) motility.
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Πέμπτη 1 Φεβρουαρίου 2018
Novel Insights into NDP52 Autophagy Receptor Functioning
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Publication date: January–February 2018 Source: Materials Today, Volume 21, Issue 1 Author(s): David Bradley http://ift.tt/2BP...
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Summary 银屑病是一种常见的皮肤病,影响北欧国家大约 5‐10% 的人口和全世界超过 1.25 亿人。已证实此病与治疗依从性低(意味着人们不能坚持他们的治疗)、不健康的生活方式(例如抽烟、饮酒、体育活动减少)和因此而产生的代谢性疾病相关。银屑病患者中的抑郁频率更高,但关于...
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